Find hotels in Southeast Missouri, MO from ¥7,881

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Compare 598 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (30)
"Sweet cabin"
The price is ¥13,099
¥19,637 total
includes taxes & fees
Sep 4 - Sep 5
Postcard Cabins St. Francois

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (406)
"Great place. "
The price is ¥10,318
¥19,094 total
includes taxes & fees
Sep 7 - Sep 8
The Farmstead Hotel

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very Good, (582)
"Very friendly staff who make sure guests are taken care of! Clean, great location, and safe place to stay. "
The price is ¥7,881
¥8,974 total
includes taxes & fees
Sep 11 - Sep 12
Super 8 by Wyndham Farmington

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (501)
"Have stayed here the past 3 years during the Laid Back on I-55 Truck Show! Great place to stay! The breakfast is fantastic!! The staff does not disappoint!! "
The price is ¥14,104
¥16,144 total
includes taxes & fees
Sep 7 - Sep 8
Holiday Inn Express & Suites Perryville by IHG

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1011)
"Employees were extremely helpful and happy to help!"
The price is ¥13,245
¥14,003 total
includes taxes & fees
Sep 8 - Sep 9
Drury Inn & Suites Jackson MO

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very Good, (1000)
"Great location"
The price is ¥7,889
¥8,982 total
includes taxes & fees
Sep 14 - Sep 15
Baymont Inn and Suites by Wyndham Farmington, MO

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1001)
"We enjoyed the quick check in and how quiet the property was. "
The price is ¥10,301
¥11,621 total
includes taxes & fees
Sep 7 - Sep 8
Pear Tree Inn Cape Girardeau West

Super 8 by Wyndham Perryville

2.0 star property
8.4 out of 10, Very Good, (903)
" Love the stay and staff was great "
The price is ¥10,726
¥12,279 total
includes taxes & fees
Sep 10 - Sep 11
Super 8 by Wyndham Perryville

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (675)
"Love staying at the holiday inn ans suites "
The price is ¥20,458
¥23,394 total
includes taxes & fees
Sep 21 - Sep 22
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (988)
"The staff was beyond friendly, the free breakfast did not disappointed, and we were just genuinely happy with our stay."
The price is ¥13,245
¥14,941 total
includes taxes & fees
Sep 7 - Sep 8
Drury Inn & Suites Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
8.8 out of 10, Excellent, (609)
"Excellent place to stay. Breakfast was good and staff was friendly. "
The price is ¥12,385
¥13,404 total
includes taxes & fees
Sep 8 - Sep 9
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1006)
"Great place"
The price is ¥13,954
¥15,903 total
includes taxes & fees
Sep 19 - Sep 20
Drury Inn & Suites Hayti Caruthersville

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1005)
"Excellent place to stay "
The price is ¥10,301
¥11,621 total
includes taxes & fees
Sep 7 - Sep 8
Pear Tree Inn Cape Girardeau Near the Medical Center

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very Good, (871)
"Good stay!"
The price is ¥11,384
¥13,303 total
includes taxes & fees
Sep 21 - Sep 22
Comfort Inn Festus - St Louis South

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1000)
"The pool the happy hour was really nice very relaxed nice activities front desk was very helpful at all times"
The price is ¥13,245
¥15,228 total
includes taxes & fees
Sep 7 - Sep 8
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
9.6 out of 10, Exceptional, (1001)
"Very nice hotel and nice staff "
The price is ¥13,245
¥14,941 total
includes taxes & fees
Oct 2 - Oct 3
Drury Plaza Hotel Cape Girardeau Conference Center

Super 8 by Wyndham Potosi

2.0 star property
7.0 out of 10, Good, (366)
"The room was very good for the price."
The price is ¥7,758
¥8,474 total
includes taxes & fees
Sep 9 - Sep 10
Super 8 by Wyndham Potosi

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (407)
"From the moment we walked in we were impressed with the customer service, facility & cleanliness. We enjoyed every part of our one night stay! We would definitely stay here again "
The price is ¥15,498
¥17,482 total
includes taxes & fees
Sep 7 - Sep 8
The Riverview

Festus Inn

2.0 star property
5.8 out of 10, (35)
"This hotel was a very nice! I was expecting it to be nice but it was actually a lot nicer than I thought it was going to be!!! Will definitely stay here again in the future if I have the means/a reason too!"
The price is ¥13,317
¥15,228 total
includes taxes & fees
Sep 7 - Sep 8
Festus Inn

Echo Bluff State Park

2.5 star property
9.4 out of 10, Exceptional, (207)
"Beautiful location & very friendly staff!"
The price is ¥27,817
¥29,410 total
includes taxes & fees
Sep 8 - Sep 9
Echo Bluff State Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

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Hotels with a hot tub in Southeast Missouri you'll enjoy

These family-friendly hotels in Southeast Missouri may fit your trip

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southeast Missouri attractions

K Bridge Recreation Area

K Bridge Recreation Area

Explore the great outdoors at K Bridge Recreation Area, a lovely green space in Annapolis. While you're in the area, stroll along the riverfront.

Learn more about Southeast Missouri

Explore the family-friendly area of Southeast Missouri—restaurants, wineries, and sights from Sam A. Baker State Park to K Bridge Recreation Area.

Top Southeast Missouri Hotel Reviews

More cheap stays in Southeast Missouri

More cheap stays in Southeast Missouri

Hotels in Southeast Missouri with star-rating

Hotels in Southeast Missouri with star-rating

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Explore a world of travel with Expedia