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Our top choices for Southeast Missouri vacation homes

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Farmington
10.0 out of 10, Exceptional, (8 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
United States
Scott
The price is ¥18,840
¥35,922 total
includes taxes & fees
Jan 25 - Jan 26
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC

Clifford's Country Cottage

Clifford's Country Cottage
Bonne Terre
10.0 out of 10, Exceptional, (24 reviews)
"Wife just loved the place"
United States
Stanley H.
The price is ¥19,463
¥23,728 total
includes taxes & fees
Jan 26 - Jan 27
Clifford's Country Cottage

Charming 2-bedroom house with AC, WiFi in serene Van Buren

Charming 2-bedroom house with AC, WiFi in serene Van Buren
Van Buren
9.0 out of 10, Wonderful, (15 reviews)
"It was beautiful and homey. We really enjoyed our stay. "
United States
Jessica
The price is ¥10,899
¥26,161 total
includes taxes & fees
Jan 26 - Jan 27
Charming 2-bedroom house with AC, WiFi in serene Van Buren

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (38 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
United States
Emily D.
The price is ¥21,020
¥33,750 total
includes taxes & fees
Jan 26 - Jan 27
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Farmington
10.0 out of 10, Exceptional, (13 reviews)
"The home was very clean and well cared for. It was fully stocked with all the necessities. The bed was comfortable. I would definitely stay here again. "
United States
Billie N.
The price is ¥18,840
¥35,922 total
includes taxes & fees
Jan 25 - Jan 26
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington

Melody King Suite. Experience peaceful relaxation in this Micro Boutique Hotel

Melody King Suite. Experience peaceful relaxation in this Micro Boutique Hotel
Alton
10.0 out of 10, Exceptional, (1 review)
"Thoroughly enjoyed our stay! Room was clean, welcoming and relaxing. Hosts were pleasant, accommodating and kind. Would highly recommend. We will definitely be back! "
United States
Paula W.
The price is ¥8,595
¥11,709 total
includes taxes & fees
Feb 3 - Feb 4
Melody King Suite. Experience peaceful relaxation in this Micro Boutique Hotel

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (150 reviews)
"Such a great place and location"
United States
Tracy H.
The price is ¥23,355
¥38,139 total
includes taxes & fees
Jan 25 - Jan 26
Serenity South -- Gardens, River-Views, and Refreshing Space

"Little Brick House on Main (1865)”

"Little Brick House on Main (1865)”
Ste. Genevieve
10.0 out of 10, Exceptional, (64 reviews)
"Great place to stay!"
United States
Lettitia B.
The price is ¥18,497
¥24,725 total
includes taxes & fees
Feb 3 - Feb 4
"Little Brick House on Main (1865)”

Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Farmington
10.0 out of 10, Exceptional, (22 reviews)
"Everything about this property was amazing and perfect for our family! They were so helpful with everything and our kids loved it here!!"
United States
Heaven B.
The price is ¥17,906
¥35,298 total
includes taxes & fees
Feb 8 - Feb 9
Newly remodeled house minutes away from downtown, golf courses + BIG back yard

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very Good, (49 reviews)
"Cozy and perfect for a couple. Great communication with the host"
United States
Beth G.
The price is ¥12,612
¥15,726 total
includes taxes & fees
Jan 26 - Jan 27
Little Blue Cottage on Spanish

Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy 1-bedroom house with AC and WiFi in charming Farmington
Farmington
10.0 out of 10, Exceptional, (8 reviews)
"A very nice place to stay. It is close to everything we were interested in doing.Everything worked as advertised. "
United States
Cary B.
The price is ¥11,911
¥28,535 total
includes taxes & fees
Jan 26 - Jan 27
Cozy 1-bedroom house with AC and WiFi in charming Farmington

Cozy upstairs unit in Cape Girardeau

Cozy upstairs unit in Cape Girardeau
Cape Girardeau
The price is ¥16,816
¥19,930 total
includes taxes & fees
Jan 31 - Feb 1
Cozy upstairs unit in Cape Girardeau

Get Away Acres 1/2 mile off highway 60 extra sanitized

Get Away Acres 1/2 mile off highway 60 extra sanitized
Ellsinore
10.0 out of 10, Exceptional, (95 reviews)
"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"
United States
Anonymous traveler
The price is ¥16,349
¥20,399 total
includes taxes & fees
Jan 26 - Jan 27
Get Away Acres 1/2 mile off highway 60 extra sanitized

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch
Ironton
10.0 out of 10, Exceptional, (33 reviews)
"enjoyed our stay, nice location to downtown and coffee. "
United States
Aaron L.
The price is ¥17,641
¥37,019 total
includes taxes & fees
Jan 26 - Jan 27
*State Parks*Bungalow*CoffeeBar*Pet Friendly*Porch

Doc's Cottage - A-Frame in Piggott, AR

Doc's Cottage - A-Frame in Piggott, AR
Piggott
10.0 out of 10, Exceptional, (11 reviews)
"Very clean and well stocked. Host was excellent to communicate with. We would definitely stay again!"
United States
Ken R.
The price is ¥17,906
¥37,822 total
includes taxes & fees
Jan 28 - Jan 29
Doc's Cottage - A-Frame in Piggott, AR

Cozy Three bedroom home in Central Farmington

Cozy Three bedroom home in Central Farmington
Farmington
9.6 out of 10, Exceptional, (29 reviews)
"House was adorable and comfortable. Location close to everything. Drive to The Landing was not bad at all. Host was friendly and available. I would stay again!"
United States
Jody C.
The price is ¥16,816
¥38,078 total
includes taxes & fees
Feb 3 - Feb 4
Cozy Three bedroom home in Central Farmington

Cozy Haven Little Hidden Gem Sleeps 4

Cozy Haven Little Hidden Gem Sleeps 4
Ste.Genevieve
9.8 out of 10, Exceptional, (56 reviews)
"Wonderful place, very clean, very cozy. We had absolutely everything we needed and host was very helpful and communicative. We will definitely be back. The location is great! Super close to everything in town but also gives you a feeling like you're out in a country"
United States
alona & andrew t.
The price is ¥15,414
¥31,901 total
includes taxes & fees
Jan 25 - Jan 26
Cozy Haven Little Hidden Gem Sleeps 4

The Morning Glory - Country Cottage

The Morning Glory - Country Cottage
Piggott
10.0 out of 10, Exceptional, (3 reviews)
"Great stay. Home was just as advertised. Great communication with owner. Will visit again. "
United States
Scott C.
The price is ¥22,265
¥43,652 total
includes taxes & fees
Feb 9 - Feb 10
The Morning Glory - Country Cottage

Family-Friendly 3BR/2BA Van Buren Home w/ Fire Pit & Starlink WiFi!

Family-Friendly 3BR/2BA Van Buren Home w/ Fire Pit & Starlink WiFi!
Van Buren
The price is ¥14,267
¥29,960 total
includes taxes & fees
Jan 25 - Jan 26
Family-Friendly 3BR/2BA Van Buren Home w/ Fire Pit & Starlink WiFi!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Find out more about Southeast Missouri

Southeast Missouri Vacation Homes information

Number of reviews
615
Accommodation
190 Vacation Homes
Lowest Price
¥15,726
Highest Price
¥43,652