Photo by Henry Fitzthum
Search Vacation Homes in Southeast Missouri
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Southeast Missouri vacation homes
Vacation Home in French Village
Tiny Houses of French Village10.0 out of 10, Exceptional, (3 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
Norma
Vacation Home in Farmington
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC10.0 out of 10, Exceptional, (8 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
Scott
The price is ￥18,840
￥35,455 total
includes taxes & fees
Jan 26 - Jan 27
Vacation Home in Bonne Terre
Clifford's Country Cottage10.0 out of 10, Exceptional, (24 reviews)
"Wife just loved the place"
Stanley H.
The price is ￥19,463
￥23,728 total
includes taxes & fees
Jan 26 - Jan 27
Vacation Home in Van Buren
Charming 2-bedroom house with AC, WiFi in serene Van Buren9.0 out of 10, Wonderful, (15 reviews)
"It was beautiful and homey. We really enjoyed our stay. "
Jessica
The price is ￥10,899
￥26,161 total
includes taxes & fees
Jan 26 - Jan 27
Vacation Home in Cape Girardeau
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool8.8 out of 10, Excellent, (38 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
Emily D.
The price is ￥21,020
￥33,750 total
includes taxes & fees
Jan 26 - Jan 27
Vacation Home in Farmington
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington10.0 out of 10, Exceptional, (13 reviews)
"The home was very clean and well cared for. It was fully stocked with all the necessities. The bed was comfortable. I would definitely stay here again. "
Billie N.
The price is ￥18,840
￥35,455 total
includes taxes & fees
Jan 26 - Jan 27
Vacation Home in Alton
Melody King Suite. Experience peaceful relaxation in this Micro Boutique Hotel10.0 out of 10, Exceptional, (1 review)
"Thoroughly enjoyed our stay! Room was clean, welcoming and relaxing. Hosts were pleasant, accommodating and kind. Would highly recommend. We will definitely be back! "
Paula W.
The price is ￥8,595
￥11,709 total
includes taxes & fees
Feb 3 - Feb 4
Vacation Home in Cape Girardeau
Serenity South -- Gardens, River-Views, and Refreshing Space10.0 out of 10, Exceptional, (150 reviews)
"Such a great place and location"
Tracy H.
The price is ￥23,355
￥38,139 total
includes taxes & fees
Jan 26 - Jan 27
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find vacation rentals that suit your style
Cabins
Aparthotels
Save an average of 15% on thousands of hotels when you're signed in
Top Southeast Missouri Hotel Reviews
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
Find out more about Southeast Missouri
Southeast Missouri Vacation Homes information
Number of reviews | 615 |
|---|---|
Accommodation | 190 Vacation Homes |
Lowest Price | ￥15,726 |
Highest Price | ￥40,495 |
Explore a world of travel with Expedia
- Ski Hotels in Farmington
- Poplar Bluff Hotels
- Luxury Hotels in Belgrade
- Rv Parks in Jackson
- Guest Houses in Sikeston
- Dexter Hotels
- Aparthotels in Ellington
- Rv Parks in Southeast Missouri
- Motels in Black
- Black Hotels
- Bunker Hotels
- Pet-Friendly Hotels in Farmington
- B&B in Annapolis
- Motels in Jackson
- B&B in Ste Genevieve
- Luxury Hotels in Sikeston
- Rv Parks in Black
- Luxury Hotels in Bloomfield
- Apartments in Cape Girardeau County
- Hotels near Washington State Park
- Doniphan Hotels
- Cape Girardeau Hotels