
Find hotels in Southern Illinois, IL from ¥9,335
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Go beyond your typical stay in Southern Illinois
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Sep 15 - Sep 16Tomorrow
Sep 16 - Sep 17This weekend
Sep 18 - Sep 20Next weekend
Sep 25 - Sep 27Our top choices for Southern Illinois hotels




1. Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
Kirstyn
¥17,049
¥19,228 total
includes taxes & fees
Sep 20 - Sep 21




2. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
John
¥18,126
¥20,423 total
includes taxes & fees
Sep 27 - Sep 28




3. Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
James
¥18,317
¥20,638 total
includes taxes & fees
Oct 4 - Oct 5




4. Rodeway Inn Mount Vernon, IL
Rodeway Inn Mount Vernon, ILMount Vernon
Emil
¥10,445
¥11,899 total
includes taxes & fees
Sep 16 - Sep 17




5. Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon ILMount Vernon
Matthew W,
¥11,214
¥12,753 total
includes taxes & fees
Sep 17 - Sep 18




6. Quality Inn Mount Vernon, IL
Quality Inn Mount Vernon, ILMount Vernon
Matthew
¥11,613
¥13,196 total
includes taxes & fees
Sep 27 - Sep 28




7. Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
Larry
¥14,538
¥16,134 total
includes taxes & fees
Sep 20 - Sep 21




8. SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
MARK
¥12,493
¥13,865 total
includes taxes & fees
Sep 29 - Sep 30




9. Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
Tina
¥11,753
¥13,043 total
includes taxes & fees
Sep 22 - Sep 23




10. Best Western Delta Inn
Best Western Delta InnEffingham
Chris
¥13,272
¥14,862 total
includes taxes & fees
Sep 20 - Sep 21




11. Quality Inn & Suites Metropolis I-24
Quality Inn & Suites Metropolis I-24Metropolis
Cierra
¥8,684
¥10,097 total
includes taxes & fees
Sep 27 - Sep 28




12. Holiday Inn Express Metropolis by IHG
Holiday Inn Express Metropolis by IHGMetropolis
Benjamin
¥14,900
¥16,536 total
includes taxes & fees
Sep 20 - Sep 21




13. DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. VernonMount Vernon
Samuel
¥19,725
¥22,201 total
includes taxes & fees
Oct 1 - Oct 2




14. Super 8 by Wyndham Troy IL/St. Louis Area
Super 8 by Wyndham Troy IL/St. Louis AreaTroy
Esmeralda
¥10,445
¥11,593 total
includes taxes & fees
Sep 21 - Sep 22




15. Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
Justin
¥16,828
¥19,180 total
includes taxes & fees
Sep 27 - Sep 28




16. Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
Heidi
¥16,588
¥17,912 total
includes taxes & fees
Sep 16 - Sep 17




17. La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
Alexis
¥17,366
¥19,447 total
includes taxes & fees
Sep 20 - Sep 21




18. Ramada by Wyndham Effingham
Ramada by Wyndham EffinghamEffingham
Kristen
¥10,220
¥11,444 total
includes taxes & fees
Sep 20 - Sep 21




19. Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
Sierra
¥12,314
¥13,666 total
includes taxes & fees
Sep 24 - Sep 25




20. Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
Kate
¥18,846
¥20,915 total
includes taxes & fees
Sep 27 - Sep 28
Vacation Rentals in Southern Illinois
Cottage




Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg Home w/ Private Yard + Screened Porch!Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Cottage




Illinois Vacation Rental Home: Pets Welcome
Illinois Vacation Rental Home: Pets WelcomePalestine
Cottage




Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!Anna
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
Cottage




Country Home Near EIU & Lake Charleston!
Country Home Near EIU & Lake Charleston!Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Cottage




Peaceful Robinson Home w/ Yard, Near Golf Courses!
Peaceful Robinson Home w/ Yard, Near Golf Courses!Robinson
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Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
Harrah's Metropolis
8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
See all hotels in Southern Illinois
Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Great job clean room good breakfast"
Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"Room was nicely decorated and clean, bed and pillows very comfortable, staff friendly and helpful, breakfast was delicious. Only downside was air conditioning loud with a scratching sound with blower"
Motel 6 Caseyville, IL - Caseyville Il
10/10 Excellent
"Clean. Friendly staff good prices"
Quality Inn O'Fallon - St. Louis - Shiloh
8/10 Good
"The room was good but breakfast sucks. Not many choices; just waffles, two kinds of cereal, and toast or bagels. On the plus side there is a Starbucks just pass the entrance/exit of the parking lot."
Ramada by Wyndham Effingham
10/10 Excellent
"Everything was great and great location and great breakfast."
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"The amenities where excellent and offered more then other places offer. The staff were kind d and friendly. The rooms where clean, comfortable, and up to what you wa t feom a hotel stay.I would stay there again."
Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
10/10 Excellent
"I enjoyed my stay at Harrahs. The hotel was nice and clean. The staff was friendly and helpful. I ordered room service food from the grill which arrived quickly and tasted fresh. The only thing I was wondering was why The Bridges didn't have room service. I did go to Bridges for breakfast and it tasted fresh and flavorful. I enjoyed the casino with had a good selection of slots, but I would stay there even without gaming. I enjoyed it very much."
Comfort Suites Fairview Heights - St. Louis
8/10 Good
"There was a smell in our room that was very strong. Other than that it was clean."
More cheap stays in Southern Illinois

Americas Best Value Inn Collinsville St. Louis
552 Ramada Blvd Collinsville IL
¥8,118
¥9,335 total
Oct 11 - Oct 12
includes taxes & fees

Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
¥8,226
¥9,458 total
Sep 21 - Sep 22
includes taxes & fees

Best Western Delta Inn
1509 Hampton Dr Effingham IL
¥13,272
¥14,862 total
Sep 20 - Sep 21
includes taxes & fees
9/10 Wonderful! (1,002 reviews)

Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney Effingham IL
¥14,538
¥16,134 total
Sep 20 - Sep 21
includes taxes & fees

Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
¥14,101
¥16,213 total
Sep 21 - Sep 22
includes taxes & fees

Baymont by Wyndham Marion
2608 W Main St Marion IL
¥14,447
¥17,333 total
Sep 27 - Sep 28
includes taxes & fees
8.4/10 Very Good! (1,095 reviews)
Hotels in Southern Illinois with star-rating

4 Star Hotels
4 properties

3 Star Hotels
82 properties

2 Star Hotels
218 properties
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