Southern Illinois Vacations

Book a Hotel + Flight or Car together to unlock savings

Photo by Southernmost Illinois Tourism Bureau

  • Plan, book, travel with confidence

    • payments icon

    Better together

    Save up to ￥45,448 when you book a flight and hotel together*
    lob hotels icon

    Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon

    Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Southern Illinois

Find the best Southern Illinois areas and neighborhoods for the activities you enjoy most. Learn more about Southern Illinois
Default Image

Eastport

If you're spending some time in Eastport, Gateway Conference Center and Splash City Family Waterpark are top sights worth seeing.

Find hotels in Eastport

Find the Best Southern Illinois Vacation Packages

Southern Illinois Hotel Deals

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

3 out of 5
145 North 44th Street , Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is ￥14,279 per night from Aug 17 to Aug 18
￥14,279
￥16,141 total
Aug 17 - Aug 18
includes taxes & fees
9.6/10 Exceptional! (1,405 reviews)
Best hotel! Great food!
"This is the best hotel we've ever stayed at in the U.S. comfy, friendly, bar + restaurant inside, pool & hot tub, soft sheets, plenty of pillows, quiet (except for our own snoring). We are now loyal customers!"

Reviewed on Aug 6, 2025

Drury Plaza Hotel Mt. Vernon
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

3 out of 5
4 Regency Pkwy, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is ￥13,248 per night from Aug 10 to Aug 11
￥13,248
￥14,702 total
Aug 10 - Aug 11
includes taxes & fees
8.4/10 Very Good! (719 reviews)
"It was very convenient to area attractions like St. Louis and the race track at World Technology."

Reviewed on Aug 2, 2025

Best Western Plus Pontoon Beach
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

2.5 out of 5
1240 E Chain Of Rocks Rd, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is ￥9,937 per night from Aug 8 to Aug 9
￥9,937
￥11,250 total
Aug 8 - Aug 9
includes taxes & fees
7.8/10 Good! (475 reviews)
"Good place for the money"

Reviewed on Aug 3, 2025

Red Lion Inn & Suites Pontoon Beach
See all 1,044 properties in Southern Illinois
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Southern Illinois

Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

4.5/5(173 reviews)

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Southern Illinois University
Superman Statue which includes a statue or sculpture as well as a small group of people

Superman Statue

4.5/5(104 reviews)

Superman fans will love getting a photograph taken in front of this giant statue of the Man of Steel himself, dressed in his iconic red-and-blue guise.

Superman Statue
Monk's Mound covers almost 14 acres and rises 100 feet. A part of the larger ancient city of Cahokia that at its peak housed 10-15 thousand people.

Cahokia Mounds State Historic Site

4.5/5(4 reviews)

You can learn about the history of Collinsville when you stop by Cahokia Mounds State Historic Site. Discover the great live music in this walkable area, or seek out the local tours.

Cahokia Mounds State Historic Site

Frequently asked questions

How much does a Southern Illinois vacation package cost?
From just , you can tailor make your Southern Illinois vacation package. Simply bundle hotels, flights and car rentals and be rewarded with discounts.
How do I get a cheap travel package to Southern Illinois?
Bundle your flights and hotels with Expedia to save big on your next big adventure. With over 550 airlines and 1,000,000 hotels globally, your Southern Illinois vacation package can be tailored exactly to suit your budget. With all that extra money, why not throw in one or more awesome activities and tours? It's an easy way to unlock even more discounts. Your dream getaway to Southern Illinois is much closer than you thought!
What are the top hotels in Southern Illinois?
Take a look at Super 8 by Wyndham Carbondale and Best Western Saluki Inn. They're top picks for lots of travelers to Carbondale. If Marion is on your travel itinerary, Super 8 by Wyndham Marion and Quality Inn And Suites are a couple of popular options.
How far in advance should I book my Southern Illinois vacation?
Reward yourself with the widest variety at the lowest prices by booking your vacation to Southern Illinois early. Air carriers usually sell flight tickets around 12 months before departure, so reserve your spot ASAP. That said, Expedia is dedicated to giving you the best bargains around, so it's never a bad time to book your dream vacation!
What does an Expedia Southern Illinois travel package include?
That depends on what sort of trip you're contemplating. Southern Illinois vacation deals can include flights, hotels and car rentals. You can mix and match to create the travel package that suits you. You can also add on experiences and activities after you've booked to get even bigger discounts.
What should I know before booking a Southern Illinois travel package?
You'll score excellent savings when you combine your flights, hotels and rental cars into a package. Not only that, booking everything in one spot will make your trip planning easier. So why waste your money or time? Whether you're organizing a ritzy city getaway or a low-cost family road trip, explore our vacation packages today.
Can I choose my airline with a Southern Illinois Expedia vacation package?
You can, and with more than 550 airlines to pick from across the globe, you're not short on choice. Browse the available options and see which airline fits your needs and budget.
If I'm not able to travel, can I cancel my Southern Illinois vacation package?
You can cancel your Southern Illinois booking if your plans have changed. Whether you'll be charged a fee or not depends on your airline, hotel or car rental company. It may be possible to cancel or change for free if you booked in the last 24 hours. Visit our Customer Service Portal to learn more.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.