Find hotels in Southern Illinois, IL from ￥9,492
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Sep 8 - Sep 9Tomorrow
Sep 9 - Sep 10This weekend
Sep 11 - Sep 13Next weekend
Sep 18 - Sep 20Our top choices for Southern Illinois hotels
1. Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
Kirstyn
￥17,109
￥19,295 total
includes taxes & fees
Sep 20 - Sep 21
2. Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
Abigail
￥18,190
￥20,495 total
includes taxes & fees
Sep 27 - Sep 28
3. Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
James
￥18,129
￥20,427 total
includes taxes & fees
Sep 20 - Sep 21
4. Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
Justin
￥16,887
￥19,247 total
includes taxes & fees
Sep 10 - Sep 11
5. Super 8 by Wyndham Mt. Vernon IL
Super 8 by Wyndham Mt. Vernon ILMount Vernon
Matthew W,
￥12,024
￥13,652 total
includes taxes & fees
Sep 10 - Sep 11
6. Quality Inn Mount Vernon, IL
Quality Inn Mount Vernon, ILMount Vernon
Matthew
￥11,654
￥13,242 total
includes taxes & fees
Sep 20 - Sep 21
7. Days Inn by Wyndham Mount Vernon
Days Inn by Wyndham Mount VernonMount Vernon
Asa
￥11,137
￥12,668 total
includes taxes & fees
Sep 20 - Sep 21
8. SureStay Hotel by Best Western Whittington Rend Lake
SureStay Hotel by Best Western Whittington Rend LakeWhittington
MARK
￥12,485
￥13,857 total
includes taxes & fees
Sep 14 - Sep 15
9. Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
Larry
￥14,589
￥16,191 total
includes taxes & fees
Sep 15 - Sep 16
10. DoubleTree by Hilton Mt. Vernon
DoubleTree by Hilton Mt. VernonMount Vernon
Samuel
￥19,713
￥22,185 total
includes taxes & fees
Oct 1 - Oct 2
11. Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
Kate
￥20,098
￥22,305 total
includes taxes & fees
Oct 4 - Oct 5
12. Holiday Inn Express Metropolis by IHG
Holiday Inn Express Metropolis by IHGMetropolis
Benjamin
￥14,953
￥16,594 total
includes taxes & fees
Sep 13 - Sep 14
13. Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
Donna
￥16,313
￥17,614 total
includes taxes & fees
Sep 16 - Sep 17
14. Best Western Plus Centralia Hotel & Suites
Best Western Plus Centralia Hotel & SuitesCentralia
Corey
￥21,427
￥23,994 total
includes taxes & fees
Sep 13 - Sep 14
15. Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
jamie
￥11,794
￥13,088 total
includes taxes & fees
Sep 15 - Sep 16
16. Best Western Delta Inn
Best Western Delta InnEffingham
Chris
￥13,813
￥15,467 total
includes taxes & fees
Sep 13 - Sep 14
17. Harrah's Metropolis Hotel & Casino - A Caesars Rewards Destination
Harrah's Metropolis Hotel & Casino - A Caesars Rewards DestinationMetropolis
Jason
￥14,234
￥18,264 total
includes taxes & fees
Oct 7 - Oct 8
18. Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
Suzanne
￥14,180
￥17,013 total
includes taxes & fees
Sep 20 - Sep 21
19. Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
Sierra
￥11,990
￥13,306 total
includes taxes & fees
Sep 20 - Sep 21
20. La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
Alexis
￥17,820
￥19,954 total
includes taxes & fees
Sep 15 - Sep 16
Vacation Rentals in Southern Illinois
Cottage
Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg Home w/ Private Yard + Screened Porch!Harrisburg
"We love how accommodating, helpful and responsive Hollie and Clayton were. The rental had everything we needed and then some. Very clean, cozy and comfortable. We chose this location, because it was close to the different parks and trails we had visited. Thank you, Hollie and Clayton, for being such gracious hosts."
Cottage
Peaceful Robinson Home w/ Yard, Near Golf Courses!
Peaceful Robinson Home w/ Yard, Near Golf Courses!Robinson
Cottage
Cozy Anna Home Near Southern Illinois Attractions!
Cozy Anna Home Near Southern Illinois Attractions!Anna
"Good communication with the owners. Nice perks such as coffee, tea, and hygiene items."
Cottage
Illinois Vacation Rental Home: Pets Welcome
Illinois Vacation Rental Home: Pets WelcomePalestine
Cottage
Country Home Near EIU & Lake Charleston!
Country Home Near EIU & Lake Charleston!Charleston
"Property was very clean and beautifully decorated in a farmhouse style. Very cozy and comfortable! Came stocked with everything you would need. We had fun at nearby Aikman Wildlife Adventure in Arcola, Kayaking in Lake Charleston, hiking in Fox Ridge State Park a visit to Amish country in Arthur, IL. The kitchen, living and dining room were very spacious! The bathroom was very tiny so if staying with 4 adults - be prepared for this. Also there was a strange odor right outside the front entry...
Cottage
Mins to Local Attractions: Pet Friendly w/ Yard!
Mins to Local Attractions: Pet Friendly w/ Yard!Casey
"Property was very clean and quiet, will definitely schedule for next family reunion."
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Stay near popular Southern Illinois attractions
Garden of the Gods Recreation Area
9.8/10 (63 reviews)
See for yourself why Harrisburg’s unearthly sandstone formations, tucked within lush Shawnee National Forest, earn their ethereal name.
World Wide Technology Raceway
9.0/10 (2 reviews)
Catch an event at World Wide Technology Raceway during your trip to St. Louis. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
O'Fallon Family Sports Park
8.6/10 (137 reviews)
This sports complex features premium turf fields, splash pads, and fishing ponds in a family-friendly setting. Watch tournaments or enjoy the scenic walking trail that winds around natural areas.
Harrah's Metropolis
8.0/10 (310 reviews)
This riverside casino offers over 600 slot machines and 17 table games along the scenic Ohio River. Join the rewards program to maximize your experience while enjoying Southern classics at the on-site restaurants.
Learn more about Southern Illinois
Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.
See all hotels in Southern Illinois
Photo by Southernmost Illinois Tourism Bureau
Top Southern Illinois Hotel Reviews
Drury Plaza Hotel Mt. Vernon
10/10 Excellent
"Room was clean and comfortable. Staff were friendly and helpful. Area was convenient to shopping and restaurants. 10 out of 10."
The Principal Hotel
10/10 Excellent
"I really enjoyed staying at the Principal. The hotel staff are very friendly and helpful. The room was large with gorgeous big windows and was very quiet. The room and bathroom were clean with plenty of towels and extra blankets and pillows. The beds were very comfortable and clean as well. I have already recommended the hotel to other travelers!"
Super 8 by Wyndham O'Fallon
10/10 Excellent
"Clean room"
Holiday Inn Express Metropolis by IHG
10/10 Excellent
"Very nice people. Very clean. Good breakfast"
Drury Inn & Suites St. Louis Fairview Heights
10/10 Excellent
"My son and I stayed here for a couple of days while I was in town visiting family over Labor Day weekend. The front desk person, Romello (sorry if I spelled your name wrong), was super nice and welcoming. All of the other staff we encountered throughout our stay were great as well. My son especially loved the pool. It was definitely his favorite part of the stay. The Marketplace downstairs was also really convenient for grabbing a quick snack or something to drink without having to leave the hotel. Overall, we had a great stay and really enjoyed our time here. We would definitely stay again when we’re back in town."
Comfort Suites Mount Vernon
10/10 Excellent
"Nice staff at front desk"
Motel 6 Caseyville, IL - Caseyville Il
8/10 Good
"thanks"
Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
"It was Very loud some nights. And the hallways smelt like marijuana. Next time I think we will be staying some where else."
Comfort Inn Edwardsville - St. Louis
10/10 Excellent
"This is a very solid hotel. The room was clean and pretty large. The breakfast had lots of options. And the fitness center was decent--two treadmills, an elliptical, and free weights in a nice clean room. There's also a pool. And theres lots of stuff nearby for shopping and eating."
More cheap stays in Southern Illinois
Super 8 by Wyndham O'Fallon
1100 Eastgate Dr O'Fallon IL
￥8,255
￥9,492 total
Sep 22 - Sep 23
includes taxes & fees
6.6/10 (1,092 reviews)
Americas Best Value Inn Collinsville St. Louis
552 Ramada Blvd Collinsville IL
￥8,495
￥9,767 total
Oct 5 - Oct 6
includes taxes & fees
6.4/10 (968 reviews)
Best Western Delta Inn
1509 Hampton Dr Effingham IL
￥13,813
￥15,467 total
Sep 13 - Sep 14
includes taxes & fees
9/10 Wonderful! (1,006 reviews)
Baymont by Wyndham Marion
2608 W Main St Marion IL
￥13,473
￥16,166 total
Sep 22 - Sep 23
includes taxes & fees
Country Inn & Suites by Radisson, Effingham, IL
1200 N Raney Effingham IL
￥14,589
￥16,191 total
Sep 15 - Sep 16
includes taxes & fees
Comfort Inn Edwardsville - St. Louis
3080 S State Route 157 Edwardsville IL
￥15,415
￥17,724 total
Sep 28 - Sep 29
includes taxes & fees
8.4/10 Very Good! (928 reviews)
Hotels in Southern Illinois with star-rating
4 Star Hotels
4 properties
3 Star Hotels
82 properties
2 Star Hotels
218 properties
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