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Find hotels in Southern Illinois, IL from ¥8,550
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Our top choices for Southern Illinois hotels

Drury Plaza Hotel Mt. Vernon
Drury Plaza Hotel Mt. VernonMount Vernon
9.6 out of 10, Exceptional, (1,718 reviews)
The price is ¥20,659
¥23,247 total
includes taxes & fees
Jul 4 - Jul 5

Holiday Inn Express & Suites Effingham by IHG
Holiday Inn Express & Suites Effingham by IHGEffingham
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ¥20,340
¥22,776 total
includes taxes & fees
Jun 21 - Jun 22

Comfort Suites Mount Vernon
Comfort Suites Mount VernonMount Vernon
9.0 out of 10, Wonderful, (1,052 reviews)
The price is ¥18,106
¥20,414 total
includes taxes & fees
Jun 14 - Jun 15

Hampton Inn & Suites Effingham
Hampton Inn & Suites EffinghamEffingham
9.6 out of 10, Exceptional, (740 reviews)
The price is ¥23,431
¥26,004 total
includes taxes & fees
Jun 28 - Jun 29

Drury Inn & Suites Marion
Drury Inn & Suites MarionMarion
9.4 out of 10, Exceptional, (1,013 reviews)
The price is ¥18,577
¥22,289 total
includes taxes & fees
Jun 28 - Jun 29

Holiday Inn Effingham by IHG
Holiday Inn Effingham by IHGEffingham
9.2 out of 10, Wonderful, (687 reviews)
The price is ¥16,176
¥18,113 total
includes taxes & fees
Jun 21 - Jun 22

Best Western Plus MidAmerica Hotel
Best Western Plus MidAmerica HotelMascoutah
9.0 out of 10, Wonderful, (1,004 reviews)
The price is ¥18,250
¥20,802 total
includes taxes & fees
Jul 5 - Jul 6

Cobblestone Inn & Suites - Altamont
Cobblestone Inn & Suites - AltamontAltamont
9.6 out of 10, Exceptional, (874 reviews)
The price is ¥14,269
¥15,407 total
includes taxes & fees
Jun 10 - Jun 11

Country Inn & Suites by Radisson, Effingham, IL
Country Inn & Suites by Radisson, Effingham, ILEffingham
8.8 out of 10, Excellent, (1,012 reviews)
The price is ¥15,209
¥16,879 total
includes taxes & fees
Jul 9 - Jul 10

La Quinta Inn & Suites by Wyndham Effingham
La Quinta Inn & Suites by Wyndham EffinghamEffingham
9.2 out of 10, Wonderful, (1,012 reviews)
The price is ¥17,425
¥19,512 total
includes taxes & fees
Jun 14 - Jun 15

Baymont by Wyndham Effingham
Baymont by Wyndham EffinghamEffingham
8.2 out of 10, Very Good, (1,015 reviews)
The price is ¥12,933
¥14,353 total
includes taxes & fees
Jun 16 - Jun 17

Holiday Inn Express & Suites Mount Vernon by IHG
Holiday Inn Express & Suites Mount Vernon by IHGMount Vernon
9.0 out of 10, Wonderful, (1,005 reviews)
The price is ¥20,340
¥22,894 total
includes taxes & fees
Jul 4 - Jul 5

Comfort Inn & Suites Marion I-57
Comfort Inn & Suites Marion I-57Marion
9.4 out of 10, Exceptional, (1,005 reviews)
The price is ¥19,780
¥23,732 total
includes taxes & fees
Jun 14 - Jun 15

Quality Inn Effingham North
Quality Inn Effingham NorthEffingham
8.4 out of 10, Very Good, (1,004 reviews)
The price is ¥14,452
¥16,038 total
includes taxes & fees
Jun 21 - Jun 22

Ramada by Wyndham Vandalia
Ramada by Wyndham VandaliaVandalia
7.8 out of 10, Good, (842 reviews)
The price is ¥13,614
¥14,836 total
includes taxes & fees
Jun 14 - Jun 15

Quality Inn & Suites Vandalia near I-70 and Hwy 51
Quality Inn & Suites Vandalia near I-70 and Hwy 51Vandalia
8.4 out of 10, Very Good, (1,007 reviews)
The price is ¥11,845
¥12,908 total
includes taxes & fees
Jun 14 - Jun 15

Best Western Plus Parkside Inn & Suites
Best Western Plus Parkside Inn & SuitesOlney
9.8 out of 10, Exceptional, (351 reviews)
The price is ¥20,284
¥22,511 total
includes taxes & fees
Jun 21 - Jun 22

Suite Dreams Hotel
Suite Dreams HotelMattoon
10.0 out of 10, Exceptional, (1 review)
The price is ¥13,998
¥15,675 total
includes taxes & fees
Jun 10 - Jun 11

Best Western Delta Inn
Best Western Delta InnEffingham
9.0 out of 10, Wonderful, (1,006 reviews)
The price is ¥14,606
¥16,356 total
includes taxes & fees
Jun 28 - Jun 29

The Principal Hotel
The Principal HotelColumbia
9.6 out of 10, Exceptional, (287 reviews)
The price is ¥18,068
¥20,052 total
includes taxes & fees
Jun 11 - Jun 12
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Southern Illinois
Cottage

Harrisburg Home w/ Private Yard + Screened Porch!
Harrisburg Home w/ Private Yard + Screened Porch!Harrisburg
10.0 out of 10, Exceptional, (1 review)
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Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Photo by Southernmost Illinois Tourism Bureau
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Top Southern Illinois Hotel Reviews

Red Lion Inn & Suites Pontoon Beach
8/10 Good
More cheap stays in Southern Illinois

Welcome Suites
148 Regency Park O'Fallon IL
The price is ¥7,436 per night from Jun 14 to Jun 15
¥7,436
¥8,550 total
Jun 14 - Jun 15
includes taxes & fees
5.8/10 (272 reviews)
Hotels in Southern Illinois with star-rating

4 Star Hotels
4 properties
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