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Find Winery Hotels in Southeast Missouri, MO
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Our top choices for Southeast Missouri hotels with winery
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (677)
"Great place "
GUY
The price is ￥13,175
￥14,259 total
includes taxes & fees
Jan 7 - Jan 8, 2026
6.8 out of 10, (924)
"Room was clean and comfortable for an overnight stay"
Jack
The price is ￥12,647
￥14,462 total
includes taxes & fees
Jan 27 - Jan 28, 2026
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4
⚜️Rivertown Retreat⚜️ Lewis & Clark stayed here. King bed. Sleeps 4Ste. Genevieve
10.0 out of 10, Exceptional, (18)
"Great historic property!"
Rhonda R.
The price is ￥17,614
￥32,332 total
includes taxes & fees
Dec 28 - Dec 29
Beautiful Modern Loft In Wine Country!
Beautiful Modern Loft In Wine Country!Ste. Genevieve
10.0 out of 10, Exceptional, (271)
"Loved our stay here! Thoughtful amenities on a beautiful property. Great communication with host. "
Elsie H.
The price is ￥23,172
￥28,290 total
includes taxes & fees
Dec 30 - Dec 31
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous FarmingtonFarmington
10.0 out of 10, Exceptional, (13)
"Great place and very comfortable! Hosts were super attentive when our door code didn’t work and got us sorted out right away. "
Kyser B.
The price is ￥18,945
￥36,592 total
includes taxes & fees
Dec 28 - Dec 29
The Weber Farm - Enjoy a beautiful 100 acre farm!
The Weber Farm - Enjoy a beautiful 100 acre farm!Frohna
10.0 out of 10, Exceptional, (32)
"Hosts were great. I just wish they had a second bath or atleast a larger bathroom. "
Dennis H.
The price is ￥14,937
￥26,025 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.Bloomsdale
10.0 out of 10, Exceptional, (8)
"What a beautiful fun stay that was a nice quick getaway for us! Everything was perfect from booking, to arrival, to overall stay, we had the best time! "
Blake H.
The price is ￥28,183
￥43,414 total
includes taxes & fees
Dec 28 - Dec 29
"Little Brick House on Main (1865)”
"Little Brick House on Main (1865)”Ste. Genevieve
10.0 out of 10, Exceptional, (63)
"Great place to stay!"
Lettitia B.
The price is ￥18,601
￥24,864 total
includes taxes & fees
Dec 28 - Dec 29
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Jackson MO
10/10 Excellent
Baymont Inn and Suites by Wyndham Farmington, MO
10/10 Excellent
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