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Serenity South -- Gardens, River-Views, and Refreshing Space

Riverfront vacation home with kitchen and balcony

Photo gallery for Serenity South -- Gardens, River-Views, and Refreshing Space

Fridge, microwave, oven, stovetop
Outdoor dining
Interior
Dining
Fridge, microwave, oven, stovetop
In the heart of Cape Girardeau Historic District, this beautifully renovated duplex offers a cozy living room and large dining room perfect for relaxation. Explore downtown's local restaurants, antique shops, and boutiques within walking distance or unwind on the balcony overlooking the shared yard.

Reviews

10 out of 10
Exceptional

Entire home

3 bedrooms2 bathroomsSleeps 5149 sq m

Popular amenities

  • Kitchen
  • Fireplace
  • Parking available
  • Outdoor Space

Add dates for prices

About this property

Entire place

You'll have the entire home to yourself and will only share it with other guests in your party.

Serenity South -- Gardens, River-Views, and Refreshing Space

Beautifully renovated duplex with large shared yard in Cape Girardeau Historic District. Cozy living room, large dining room, fully stocked kitchen, 3 second-story bedrooms with balcony at the end of the hall, and 1 1/2 bathes. Perfect for getting away for rejuvenation or exploring downtown. Within walking distance to local downtown restaurants, antique shops, and boutiques. Two blocks from the Mississippi River and many other attractions.

Property amenities

Internet

  • Available in the house: WiFi

Parking and transportation

  • Car not required
  • Parking on site

Kitchen

  • Coffee grinder
  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Ice maker
  • Microwave
  • Oven
  • Paper towels
  • Refrigerator
  • Spices
  • Stovetop
  • Toaster

Bedrooms

  • 3 bedrooms
  • Bedsheets provided

Bathroom

  • 1.5 bathrooms
  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Living spaces

  • Fireplace
  • Living room
  • Separate dining area

Entertainment

  • Books
  • DVD player
  • Games
  • TV

Outdoor areas

  • Balcony
  • Garden
  • Outdoor furniture

Laundry

  • Laundromat nearby

Comfort

  • Air conditioning
  • Heating

Pets

  • No pets allowed

Suitability/Accessibility

  • Smoking not allowed

Services and conveniences

  • Iron/ironing board

Location highlights

  • Near a health/beauty spa
  • Near a hospital
  • Near an outlet shopping mall
  • On a river

Things to do

  • Water park
  • Basketball nearby
  • Casino nearby
  • Cycling nearby
  • Fishing nearby
  • Golfing nearby
  • Hiking/biking trails nearby
  • Horseback riding nearby
  • Motor boating nearby
  • Swimming nearby
  • Wildlife walks nearby
  • Winery tours nearby

Safety features

  • Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
  • Smoke detector (host has indicated there is a smoke detector on the property)
  • Deadbolt lock

General

  • Garden
  • Unit size: 1,600 square feet

Similar properties

Fridge, microwave, oven, stovetop
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO
  • Kitchen
  • Free WiFi
  • Air conditioning
  • Outdoor Space
9.6 out of 10, Exceptional, 43 reviews
The price is ￥12,658
￥21,381 total
includes taxes & fees
Nov 30 - Dec 1
Artistic and Creative Vibe with Indoor Swing 2 Blocks to Downtown & near SEMO

Policies

Check-in

Check-in time starts at 4:00 PM
Minimum check-in age: 18

Check-out

Check-out before 11:00 AM

Special check-in instructions

You will receive an email from the host with check-in and check-out instructions

Rules

Back yard is shared with the other side of the duplex. Please respect their use of the common space.

Pets

Pets not allowed

Children and extra beds

Children are welcome
Note from host: Excellent fenced back yard.

Events

Events allowed: family gatherings, birthday parties, weddings
Parties or events must okayed before arrival.

Smoking

Smoking is not permitted

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Parties and events (including family gatherings, birthday parties and weddings) are allowed on site; maximum attendees: 50
Note from host: Parties or events must okayed before arrival.
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation

We should mention

A car is not required for transportation to and from this property

About the neighborhood

Map
MO, Cape Girardeau

What's nearby

  • eDen Spa & Salon - 2 min walk - 0.2 km
  • Riverfront Park - 2 min walk - 0.2 km
  • Riverfront Bridge Park - 5 min walk - 0.4 km
  • Isle Casino Cape Girardeau - 16 min walk - 1.4 km
  • Southeast Missouri State University - 2 min drive - 1.8 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 12 min drive

Restaurants

  • ‪Sand's Pancake House - ‬11 min walk
  • ‪Katy O'Ferrell's Publick House - ‬9 min walk
  • ‪Hotshots Sports Bar & Grill - ‬5 min walk
  • ‪Minglewood Brewery - ‬7 min walk
  • ‪The Library - ‬3 min walk

Frequently asked questions

Is Serenity South -- Gardens, River-Views, and Refreshing Space pet-friendly?

No, pets are not allowed at this property.

How much does it cost to stay at Serenity South -- Gardens, River-Views, and Refreshing Space?

As of Nov 18, 2025, prices found for a 1-night stay for 2 adults at Serenity South -- Gardens, River-Views, and Refreshing Space on Nov 19, 2025 start from ￥23,183, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking?

Onsite parking is available at the property.

What time is check-in at Serenity South -- Gardens, River-Views, and Refreshing Space?

Check-in begins at 4:00 PM.

What time is check-out at Serenity South -- Gardens, River-Views, and Refreshing Space?

Check-out is at 11:00 AM.

Where is Serenity South -- Gardens, River-Views, and Refreshing Space located?

This family-friendly Cape Girardeau vacation home is located on a river, steps from eDen Spa & Salon, Shawnee National Forest, and Mississippi River. Riverfront Park and Riverfront Bridge Park are also within 5 minutes.

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Reviews

Serenity South -- Gardens, River-Views, and Refreshing Space Reviews

10

Exceptional

10

Cleanliness

9.8

Location

10

Property conditions & facilities
Rating 10 - Excellent. 142 out of 146 reviews
Rating 8 - Good. 4 out of 146 reviews
Rating 6 - Okay. 0 out of 146 reviews
Rating 4 - Poor. 0 out of 146 reviews
Rating 2 - Terrible. 0 out of 146 reviews

Reviews

10/10 Excellent

Tracy H.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Such a great place and location
Stayed 2 nights in Jul 2025

10/10 Excellent

Jodie F.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Enjoyed everything! Great location!
Stayed 4 nights in Jul 2025

10/10 Excellent

Vicki R.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Beautiful house. Great stay. Would definitely stay again!
Stayed 1 night in Jun 2025

10/10 Excellent

Donna D.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Lovely as always

Moving our daughter in to the dorm at SEMO for yr 2. Been coming to this location since our trip here during her senior year of HS when she visited SEMO to audition for the musical theatre program. It is a great place to stay when you have more than 2 people.
Stayed 1 night in Aug 2025

10/10 Excellent

Penny F.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Beautiful getaway!

The property was exactly as listed with so many little touches that made it special. Communication was great and we were close to downtown shops and the casino. We will definitely stay again when we are in the area.
Stayed 2 nights in Mar 2025

10/10 Excellent

Linden S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

A Beautiful Retreat for Three Generations

Three generations found rest,beauty,& joy at Serenity South. Thoughtful touches,beautiful gardens and Cape charm made this more than a stay-it became a treasured memory. We were so appreciative of the details, the fresh flowers, homemade cookies, the coffeemaker upstairs and the books and games. The beds were all comfortable. We enjoyed this historical home and our stay.
Stayed 2 nights in May 2025

10/10 Excellent

John

Liked: Cleanliness, property conditions & facilities, communication
Great place.
Stayed 1 night in Dec 2023

10/10 Excellent

Sam E.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Downtown home with great character

My son and two brothers stayed a night in this lovely home. I travel to Cape frequently to visit my son and will definitely stay here again.
Stayed 1 night in Apr 2025

10/10 Excellent

Bryan P.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Comfortable & Clean

Great Location short walking distance to the Downtown Area with lots do do, Restaurants, Water Park, Shopping. This is the 2nd time I have stayed and it is a true delight. Very spacious and comfortable. Easy to communicate with the Owner/Manager. I will be staying there again in the future. I recommend it with 5 Stars!
Stayed 1 night in Jun 2025

10/10 Excellent

Michelle K.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Perfect home for college visit

When looking for a VRBO for our daughter's college visit, we knew the perfect place to stay! This is our second stay at Serenity South and it was just as incredible as the first visit. Clean, inviting and cozy. Thanks Jo for another beautiful stay.
Stayed 1 night in Feb 2025

10/10 Excellent

Tim B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great stay

Beautiful home, great location, well equipped kitchen.
Stayed 5 nights in Oct 2022

10/10 Excellent

Nichole C.

Liked: Cleanliness, check-in, communication, location, listing accuracy
Serenity south was welcoming comfortable and very clean. Impeccably maintained historic home. Comfortable beds, great water pressure and shower head, easy to maintain consistent temperature. Good vibes throughout. Not haunted. Beautiful outdoor space but it was too hot to use it much while we were there. Recommend stopping by the olive oil store William and Water across the street.
Stayed 3 nights in Jul 2025

10/10 Excellent

STEPHANIE L.

Liked: Cleanliness, check-in, communication, location, listing accuracy

In town for one day

Its was different, but over all it was on point.I will rebook this summer
Stayed 1 night in May 2025

10/10 Excellent

Rhonda S.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Smith Women’s Weekend

We had a wonderful time at Serenity South! The house is quiet and very clean, in walking distance of fantastic shops and fun places to eat. We look forward to returning next year!
Stayed 2 nights in Feb 2025

10/10 Excellent

Bradley T.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Peaceful place

Very nice and beautiful place super nice people
Stayed 2 nights in Jun 2024

10/10 Excellent

Terry M.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Great family getaway

Everything was perfect. From check in to check out. Great neighborhood and location.
Stayed 1 night in Apr 2024

10/10 Excellent

Candice L.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Family Graduation

The place was perfect for our stay and was close to the farmers market and downtown shops. Highly recommend for location!
Stayed 1 night in May 2024

10/10 Excellent

Danita D.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Historic charm

We loved staying at this house for SEMO family weekend! It was super clean and had everything we needed and more 😊 we will definitely try to stay here again!
Stayed 1 night in Sep 2023

10/10 Excellent

Scott R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Family visit

Nice property, real close to downtown and the river. Very relaxing
Stayed 2 nights in Sep 2024

10/10 Excellent

Steve B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Excellent choice

Very nice property. Highly recommend.
Stayed 2 nights in Oct 2024

10/10 Excellent

Nolan R., Tacoma, WA

Liked: Cleanliness, check-in, communication, location, listing accuracy

Wonderful all around!

Great location and property! Stayed with several friends and it’s offered lots of space for everyone. Very close to many downtown attractions! Would definitely stay again!
Stayed 2 nights in Oct 2019

10/10 Excellent

Tim B.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Homecoming

As always, a fantastic place to stay.
Stayed 2 nights in Oct 2023

10/10 Excellent

Cheryl R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Repeat guest

Great home away from home for our visits to Cape.
Stayed 3 nights in Aug 2023

10/10 Excellent

joe R.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Cape Girardeau

Beautiful very clean house with a lot of character
Stayed 1 night in Oct 2024

10/10 Excellent

Nicholas H.

Liked: Cleanliness, check-in, communication, location, listing accuracy

Cool vintage place in a great town

Loved it!
Stayed 1 night in Mar 2021