Photo by Bill Dillard
Find Historic Hotels in Southeast Missouri, MO
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Southeast Missouri Historic Hotels
Our top choices for Southeast Missouri historic hotels
The Weber Farm - Enjoy a beautiful 100 acre farm!
The Weber Farm - Enjoy a beautiful 100 acre farm!Frohna
10.0 out of 10, Exceptional, (32 reviews)
"We enjoyed the beautiful countryside. "
Jaymie T.
The price is ￥13,906
￥24,797 total
includes taxes & fees
Feb 12 - Feb 13
Serenity South -- Gardens, River-Views, and Refreshing Space
Serenity South -- Gardens, River-Views, and Refreshing SpaceCape Girardeau
10.0 out of 10, Exceptional, (150 reviews)
"Such a great place and location"
Tracy H.
The price is ￥23,177
￥38,106 total
includes taxes & fees
Feb 12 - Feb 13
Beautiful Modern Loft In Wine Country!
Beautiful Modern Loft In Wine Country!Ste. Genevieve
10.0 out of 10, Exceptional, (272 reviews)
"It was the perfect spot for a weekend getaway!"
Brittany P.
The price is ￥22,867
￥27,763 total
includes taxes & fees
Feb 15 - Feb 16
Chic Minimalist Gem w/ Fenced Backyard + W/D
Chic Minimalist Gem w/ Fenced Backyard + W/DPrinceton Heights
9.6 out of 10, Exceptional, (9 reviews)
"Clean, very comfortable apartment in a great location: easy walk to restaurants, coffee shops, Francis Park. Attractive, quiet, tree-lined neighborhood. Would definitely stay here again!"
Jack S.
The price is ￥7,107
￥25,674 total
includes taxes & fees
Mar 9 - Mar 10
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!The Hill
9.6 out of 10, Exceptional, (165 reviews)
"Easy access and great location. Place was kept very clean. "
Andrew P.
The price is ￥13,211
￥22,171 total
includes taxes & fees
Feb 17 - Feb 18
Charming cottage overlooking Lake Acre
Charming cottage overlooking Lake AcreDongola
10.0 out of 10, Exceptional, (102 reviews)
"Great place so peaceful and relaxing "
Paul D.
The price is ￥20,859
￥43,393 total
includes taxes & fees
Feb 17 - Feb 18
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Rest, Relax and Renew. Our log cabin experience awaits your arrival.Anna
10.0 out of 10, Exceptional, (405 reviews)
"Nice cabin and beautiful scenery! We enjoyed our stay."
Hannah G.
The price is ￥18,078
￥30,950 total
includes taxes & fees
Feb 12 - Feb 13
Love Italian? You'll love 'The Hill' NBHD. Clean & cozy 1st fl apt
Love Italian? You'll love 'The Hill' NBHD. Clean & cozy 1st fl aptSouthwest Garden
10.0 out of 10, Exceptional, (133 reviews)
"Wonderful place to stay!"
Diane M.
The price is ￥13,133
￥23,521 total
includes taxes & fees
Feb 17 - Feb 18
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Baymont Inn and Suites by Wyndham Farmington, MO
10/10 Excellent
Explore a world of travel with Expedia
- Apartments in Cape Girardeau County
- Dexter Hotels
- Poplar Bluff Hotels
- Motels in Black
- Luxury Hotels in Bloomfield
- Rv Parks in Black
- Doniphan Hotels
- Aparthotels in Ellington
- Rv Parks in Southeast Missouri
- Black Hotels
- Luxury Hotels in Belgrade
- Luxury Hotels in Sikeston
- Rv Parks in Jackson
- Bunker Hotels
- Cape Girardeau Hotels
- Hotels near Washington State Park
- B&B in Annapolis
- B&B in Ste Genevieve
- Pet-Friendly Hotels in Farmington
- Guest Houses in Sikeston
- Motels in Jackson
- Ski Hotels in Farmington