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Find Adults Only Resorts & Hotels in Southeast Missouri, MO

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Check availability on Southeast Missouri Adults Only Resorts & Hotels

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Recommended hotels in Southeast Missouri

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.6 out of 10, Exceptional, (217)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
United States
Joanne
The price is ¥21,690
¥22,932 total
includes taxes & fees
Dec 18 - Dec 19
Echo Bluff State Park

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Clean room, great location and friendly staff"
United States
Mark
The price is ¥13,928
¥16,013 total
includes taxes & fees
Dec 23 - Dec 24
Drury Inn & Suites Sikeston, MO

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1004)
"Great place and staff, very accommodating!"
United States
Megan
The price is ¥13,928
¥15,711 total
includes taxes & fees
Dec 21 - Dec 22
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (964)
"Nice room helpful staff. "
United States
Deborah
The price is ¥14,547
¥16,432 total
includes taxes & fees
Dec 25 - Dec 26
Drury Inn & Suites Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (703)
"Amazing place"
United States
Mladen
The price is ¥15,656
¥17,686 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Poplar Bluff by IHG

The Farmstead Hotel

The Farmstead Hotel
2.5 star property
Caruthersville
8.8 out of 10, Excellent, (463)
"Nice place "
United States
Debbie
The price is ¥13,233
¥15,049 total
includes taxes & fees
Jan 3 - Jan 4, 2026
The Farmstead Hotel

Fort Davidson Hotel

Fort Davidson Hotel
2.5 star property
Ironton
9.2 out of 10, Wonderful, (173)
"Friendly staff, spacious room, nice pool!!"
United States
SHARON
The price is ¥18,572
¥20,285 total
includes taxes & fees
Dec 21 - Dec 22
Fort Davidson Hotel

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (444)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is ¥15,189
¥17,198 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Sikeston

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (540)
"Clean room and pleasant staff"
United States
David
The price is ¥13,465
¥15,415 total
includes taxes & fees
Dec 25 - Dec 26
Holiday Inn Express & Suites Perryville by IHG

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (855)
"Very clean, great check in"
United States
Teresa
The price is ¥16,050
¥18,133 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Fairfield Inn & Suites by Marriott Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Southeast Missouri Hotel Reviews

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