Southwest Illinois, IL Residences from ￥10,301

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Recommended hotels in Southwest Illinois

A hotel kitchen with wooden cabinets, a coffee station, and a dining area with tables and chairs.

1. Best Western U. S. Inn

Nashville

Steven

￥20,725 total

includes taxes & fees

Nov 10 - Nov 11

A hotel reception desk with a digital display, a desk phone, and a computer. There is a sign indicating the hotel's name and services.

2. Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

Jo Ann

￥15,478 total

includes taxes & fees

Nov 15 - Nov 16

A modern dining area with multiple tables and chairs, a kitchen area with appliances, and a ceiling with recessed lighting and a circular light fixture.

3. Best Western Plus MidAmerica Hotel

Mascoutah

Charles

￥18,199 total

includes taxes & fees

Nov 15 - Nov 16

A bathroom with a sink, toilet, and a stack of towels.

4. Powhatan Motel

Pocahontas

Bob

￥16,251 total

includes taxes & fees

Nov 10 - Nov 11

A modern kitchen with wooden cabinets, a refrigerator, a coffee machine, and a microwave. There are red chairs and a table in the dining area.

5. Quality Inn Mount Vernon, IL

Mount Vernon

Ryan

￥12,981 total

includes taxes & fees

Nov 22 - Nov 23

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

6. Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

Karissa

￥18,745 total

includes taxes & fees

Nov 15 - Nov 16

A spacious lobby with a stone fireplace, a seating area with a sofa and chairs, and a television mounted on the wall.

7. SureStay Hotel by Best Western Whittington Rend Lake

Whittington

Tad

￥13,453 total

includes taxes & fees

Dec 1 - Dec 2

A neatly made bed with white linens and a dark headboard, flanked by two bedside tables with lamps.

8. The Principal Hotel

Columbia

Michael

￥16,510 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with two beds, a desk, a television, and a window with a view of the outdoors.

9. Red Bud Country Inn

Red Bud

Camille

￥13,594 total

includes taxes & fees

Nov 10 - Nov 11

A hotel lobby with a large sofa, armchairs, a Christmas tree, and a patterned carpet.

10. Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake

Mount Vernon

Susan

￥19,488 total

includes taxes & fees

Nov 12 - Nov 13

A hotel room with a large bed, a red bedspread, a bathtub, a nightstand with a lamp, and two framed pictures on the wall.

11. Seasons Inn & Suites Highland

Highland

robert

￥15,789 total

includes taxes & fees

Nov 29 - Nov 30

A hotel with a covered entrance, stone pillars, and a modern design.

12. Holiday Inn Express & Suites Mount Vernon by IHG

Mount Vernon

Doug

￥19,840 total

includes taxes & fees

Dec 10 - Dec 11

A multi-story hotel with a central entrance, illuminated by exterior lights, and a clear sky in the background.

13. Best Western Plus Centralia Hotel & Suites

Centralia

Jeremy

￥24,668 total

includes taxes & fees

Nov 10 - Nov 11

A hotel room with a desk, a lamp, a flat-screen TV, a telephone, a microwave, and a trash bin.

14. Super 8 by Wyndham Mt. Vernon IL

Mount Vernon

Leslie

￥13,156 total

includes taxes & fees

Nov 15 - Nov 16

A hotel lobby with a reception desk, seating area, and a large screen TV.

15. Comfort Suites Mount Vernon

Mount Vernon

Bruce and Robin

￥21,002 total

includes taxes & fees

Nov 15 - Nov 16

A hotel lobby with a Kitchen+Bar area, seating arrangements, and a view to the outside.

16. Drury Plaza Hotel Mt. Vernon

Mount Vernon

Mei

￥19,839 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with a large bed, two bedside tables with lamps, a window with curtains, a painting on the wall, and a radiator.

17. Laketree Inn And Suites Marion

Marion

Karen

￥13,224 total

includes taxes & fees

Dec 6 - Dec 7

An indoor swimming pool with a view of the outside, a hot tub, and a seating area with tables and chairs.

18. DoubleTree by Hilton Mt. Vernon

Mount Vernon

Tammi

￥22,809 total

includes taxes & fees

Nov 12 - Nov 13

A covered porch with a metal railing, a red carpet, and a green chair.

19. K-River Motel & Campground

Baldwin

Joyce

￥11,433 total

includes taxes & fees

Nov 10 - Nov 11

A modern indoor pool area with a blue ceiling, large windows, and a pool with a metal ladder.

20. Hampton Inn O'Fallon

O'Fallon

"The gentleman checking us in and the one checking us out were both very friendly and welcoming, plus the one checking us in was very helpful telling us about the facility we didn’t need to ask any questions… property was very bright and clean and safe. Also appeared to have been updated in the last few years, no dingy poorly lit hallways, everything well maintained, room was very spacious and clean"

Beverly

￥20,936 total

includes taxes & fees

Nov 15 - Nov 16

View all properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois

A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."

Top reviews in Southwest Illinois

Drury Plaza Hotel Mt. Vernon

Mount Vernon

10/10 Excellent

Samara

Best Western Plus Centralia Hotel & Suites

Centralia

10/10 Excellent

Omar

Drury Inn & Suites St. Louis O'Fallon, IL

O'Fallon

10/10 Excellent

Anonymous traveler

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

Drury Inn & Suites St. Louis Collinsville

Eastport

10/10 Excellent

gary

Best Western U. S. Inn

Nashville

10/10 Excellent

Anonymous traveler

Holiday Inn Express Hotel & Suites Sparta by IHG

Sparta

10/10 Excellent

stayed here for a business trip and it was perfect. Staff was very friendly, beds were comfortable, and I appreciated the "fitness center." Breakfast was also great, with a huge array of choices. My only complaint would be that there was a light right outside the window in my room (first floor) and there were no blackout curtains to hide that mean light. Even so, it was a very good overall experience and I would stay there again.

Sarah