Serra Mesa, CA

San Diego


Popular places to visit

Things to do


Serra Mesa Hotel Deals

Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive, San Diego, CA
The price is ¥22,745 per night from Oct 2 to Oct 3
¥22,745
¥30,707 total
Oct 2 - Oct 3
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy free WiFi, 3 restaurants, and breakfast (surcharge). Our guests praise the pool and the restaurant ...
8.2/10 Very Good! (5,952 reviews)
"Friendly helpful staff. Good location"

Reviewed on Sep 26, 2025

Wyndham San Diego Bayside
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl, San Diego, CA
The price is ¥32,738 per night from Oct 4 to Oct 5
¥32,738
¥46,090 total
Oct 4 - Oct 5
includes taxes & fees
Stay at this 4-star eco-certified hotel in San Diego. Enjoy free WiFi, 6 restaurants, and 3 bars/lounges. Our guests praise the pool and the bar in our reviews. ...
9/10 Wonderful! (2,811 reviews)
"The hotel is nice but more tailored for the convention fare & less of a resort ambiance. Service was efficient yet impersonal & why no concierge? They make a hotel experience."

Reviewed on Sep 22, 2025

Manchester Grand Hyatt San Diego
Bay Club Hotel & Marina

Bay Club Hotel & Marina

3.5 out of 5
2131 Shelter Island Dr, San Diego, CA
The price is ¥18,970 per night from Oct 1 to Oct 2
¥18,970
¥21,806 total
Oct 1 - Oct 2
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, a marina, and a health club. Our guests praise the breakfast and the restaurant ...
9/10 Wonderful! (2,972 reviews)
"Great calm place"

Reviewed on Sep 25, 2025

Bay Club Hotel & Marina
DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar

4 out of 5
11915 El Camino Real, San Diego, CA
The price is ¥16,900 per night from Oct 13 to Oct 14
¥16,900
¥19,256 total
Oct 13 - Oct 14
includes taxes & fees
Stay at this 4-star business-friendly hotel in San Diego. Enjoy breakfast (surcharge), room service, and a fitness center. Our guests praise the helpful staff ...
8/10 Very Good! (1,604 reviews)
"Loved area convenient and very safe!"

Reviewed on Sep 24, 2025

DoubleTree by Hilton San Diego - Del Mar
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue, San Diego, CA
The price is ¥17,819 per night from Oct 6 to Oct 7
¥17,819
¥20,660 total
Oct 6 - Oct 7
includes taxes & fees
Stay at this 3-star business-friendly hotel in San Diego. Enjoy free WiFi, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.6/10 Excellent! (461 reviews)
"I didn't think the prices to pay for breakfast or dinner were worth what we were given. It was just a bit too expensive for us."

Reviewed on Sep 23, 2025

The DEXTRO Little Italy, BW Premier Collection
Handlery Hotel

Handlery Hotel

3.5 out of 5
950 Hotel Cir N, San Diego, CA
Stay at this 3.5-star business-friendly hotel in San Diego. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the pool and the bar in our ...
8/10 Very Good! (2,124 reviews)
"Clean room, friendly staff and mall a few minutes away."

Reviewed on Sep 28, 2025

Handlery Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Serra Mesa

Default Image

Mission Valley

4/5(4,999 area reviews)

Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.

Mission Valley
Try the tamale eggs Benedict!

North Park

4/5(78 area reviews)

North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.

North Park
Loads of Loafs

Hillcrest

3.5/5(53 area reviews)

Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.

Hillcrest
Old Town San Diego State Park showing signage

Old Town San Diego

4.5/5(877 area reviews)

The ample dining options and beautiful seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.

Old Town San Diego
Little Italy

Little Italy

Little Italy is popular for its captivating waterfront views. Explore top sights like Maritime Museum of San Diego and San Diego Bay, and you can get around town on the metro at County Center - Little Italy Station.

Little Italy
Under the Ingraham Street Bridge

Crown Point

4.5/5(134 area reviews)

While visiting Crown Point, you might make a stop by sights like Mission Bay and Crown Point Shores.

Crown Point


Serra Mesa, CA