Serra Mesa, CA
San Diego
Visit Serra Mesa
Popular places to visit
San Diego Zoo
See nature up-close and personal at one of the country’s largest and most educational zoos.
San Diego Convention Center
During your trip, find out what's happening at San Diego Convention Center, a top convention center in San Diego. Experience the area's acclaimed art scene and entertainment choices.
SeaWorld
Animal interaction, entertaining rides and informative exhibits are all on offer at this family favorite destination.
Mission Bay
Mingle with eccentric locals at bohemian beaches, soak up the sun on a Jet Ski and fish from marshy islands at San Diego’s premier water park.
Balboa Park
Culture and nature converge in this diverse park located in the heart of the city.
Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.
Things to do
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego City Lights Night Tour
San Diego Whale Watching & Dolphin Cruise
Speed Boat Adventure Tour: Thrills on the San Diego Bay
San Diego: 3 Hour Whale Watching Cruise
Serra Mesa Hotel Deals
Sheraton San Diego Resort
Conveniently located to airport and town.
Reviewed on Dec 25, 2025
Bay Club Hotel & Marina
Always hate when they charge to check you in a little early. Went for a happy hour drink and snack instead, it was mediocre. Enjoyed the people and the facilities were nice. Only complaint about the room was pillows were rock hard otherwise it was clean and spacious enough
Reviewed on Dec 29, 2025
The DEXTRO Little Italy, BW Premier Collection
Staff members were very helpful. Nice property.
Reviewed on Dec 25, 2025
Courtyard by Marriott San Diego Downtown Little Italy
Didn't try the breakfast
Reviewed on Dec 23, 2025
Legacy Resort Hotel & Spa
It was very clean and very comfortable,I would definitely 😀 be here next time ☺️
Reviewed on Dec 29, 2025
San Diego Marriott La Jolla
Clean quiet rooms, friendly staff
Reviewed on Dec 28, 2025
Other neighborhoods around Serra Mesa
Mission Valley
Boasting major shopping malls like Fashion Valley Mall and Westfield Mission Valley, this area offers entertainment and historic sites such as Mission San Diego de Alcalá and Presidio Park. Easily accessible via the San Diego Trolley system's Green Line.
North Park
North Park is well-liked for its restaurants. You can also take some time to explore sights in the surrounding area like San Diego Zoo and San Diego Natural History Museum.
Hillcrest
Visitors to Hillcrest enjoy its restaurants, and if you want to do some exploring, Marston House is worth a stop.
Del Cerro
Del Cerro might not have many top sights, but Cal Coast Credit Union Open Air Theater and Viejas Arena are two attractions nearby that you can check out.
Old Town San Diego
The ample dining options and beautiful seaside views are top of the list for many visitors to Old Town San Diego. A stop by Old Town San Diego State Park or Whaley House Museum might round out your trip.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
Serra Mesa, CA
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