Find hotels in Serra Mesa, San Diego from ￥13,903

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Tonight
May 12 - May 13
Tomorrow
May 13 - May 14
Next weekend
May 17 - May 19

Discover 8,475 Serra Mesa hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Wyndham San Diego Bayside
Exterior
Wyndham San Diego Bayside
4.0 star property
8.2 out of 10, Very Good, (5915)
"I enjoyed the convenience of being right downtown . Only stayed one night but it was an eventful one night with all the local little towns and eatery’s near by . "
The price is ￥25,026
￥28,203 total
includes taxes & fees
May 28 - May 29
Wyndham San Diego Bayside
Paradise Point Resort & Spa
Aerial view
Paradise Point Resort & Spa
4.0 star property
8.4 out of 10, Very Good, (1827)
"Access to the beach "
The price is ￥31,031
￥41,999 total
includes taxes & fees
May 15 - May 16
Paradise Point Resort & Spa
The Dana on Mission Bay
Aerial view
The Dana on Mission Bay
3.5 star property
8.6 out of 10, Excellent, (2429)
"Check in was a breeze! We were offered a multitude of upgrade options. The view of the marina was stunning and the walk along the water and the sunsets were spectacular. We had dinner at the restaurant and sat outside. It was delicious and Manny our server was knowledgeable and friendly and made the experience all the more enjoyable. "
The price is ￥27,885
￥31,425 total
includes taxes & fees
May 14 - May 15
The Dana on Mission Bay
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Omni San Diego Hotel
Exterior
Omni San Diego Hotel
4.0 star property
9.0 out of 10, Wonderful, (1906)
"Great location for Petco Park and Gaslamp District"
The price is ￥32,560
￥41,962 total
includes taxes & fees
May 15 - May 16
Omni San Diego Hotel
Hilton San Diego Bayfront
Outdoor pool, sun loungers
Hilton San Diego Bayfront
4.0 star property
8.4 out of 10, Very Good, (1487)
"Valet service was great. Was able to check in early. Front desk receptionist was friendly and helpful. Room was great and clean. Stayed for one night. Check out was quick. "
The price is ￥24,208
￥34,688 total
includes taxes & fees
May 28 - May 29
Hilton San Diego Bayfront
Best Western Plus Island Palms Hotel & Marina
2 outdoor pools, sun loungers
Best Western Plus Island Palms Hotel & Marina
3.0 star property
8.8 out of 10, Excellent, (1585)
"I enjoyed my stay. The front desk staff were very kind and attentive, in a pretty location, and felt safe in the area. "
The price is ￥25,010
￥28,185 total
includes taxes & fees
May 14 - May 15
Best Western Plus Island Palms Hotel & Marina
Days Inn by Wyndham San Diego Hotel Circle
Outdoor pool, a heated pool
Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
7.6 out of 10, Good, (1923)
"They need truck parking. Stalls are to small for full sized trucks."
The price is ￥16,980
￥19,136 total
includes taxes & fees
May 14 - May 15
Days Inn by Wyndham San Diego Hotel Circle
DoubleTree by Hilton San Diego - Del Mar
Courtyard
DoubleTree by Hilton San Diego - Del Mar
4.0 star property
7.4 out of 10, Good, (1038)
"Clean and convenient "
The price is ￥19,730
￥22,196 total
includes taxes & fees
May 27 - May 28
DoubleTree by Hilton San Diego - Del Mar
Palihotel San Diego
Rooftop terrace
Palihotel San Diego
4.0 star property
8.8 out of 10, Excellent, (502)
"Stayed one night. Room was small, but comfortable. "
The price is ￥17,136
￥23,701 total
includes taxes & fees
May 28 - May 29
Palihotel San Diego
Gaslamp Plaza Suites
Lobby
Gaslamp Plaza Suites
3.5 star property
8.8 out of 10, Excellent, (1008)
"."
The price is ￥16,980
￥18,763 total
includes taxes & fees
May 15 - May 16
Gaslamp Plaza Suites
Catamaran Resort and Spa
Lobby
Catamaran Resort and Spa
4.0 star property
7.8 out of 10, Good, (1117)
"Loved the property! Got a first floor bay front room, totally worth it. Beautiful scenery, walks paths and beach access, food options everywhere. The staff were a little on the grumpy side aside from the bellhop and valet workers...we'll definitely stay again. "
The price is ￥32,558
￥43,616 total
includes taxes & fees
May 13 - May 14
Catamaran Resort and Spa
Loews Coronado Bay Resort
Exterior
Loews Coronado Bay Resort
4.0 star property
8.6 out of 10, Excellent, (1060)
"A quiet and peaceful place to relax"
The price is ￥34,116
￥44,997 total
includes taxes & fees
May 27 - May 28
Loews Coronado Bay Resort
Pendry San Diego
Front of property
Pendry San Diego
5.0 star property
9.2 out of 10, Wonderful, (1005)
"Great location and nice view "
The price is ￥43,035
￥56,229 total
includes taxes & fees
May 27 - May 28
Pendry San Diego
Kona Kai San Diego
Water view
Kona Kai San Diego
4.0 star property
8.4 out of 10, Very Good, (937)
"The resort was an amazing experience, right on the Marina with its own private beach, everything is literally in reach. The perfect getaway most definitely would book again. "
The price is ￥35,674
￥48,111 total
includes taxes & fees
May 28 - May 29
Kona Kai San Diego
Holiday Inn Express San Diego Downtown, an IHG Hotel
Pillowtop beds, in-room safe, desk, blackout drapes
Holiday Inn Express San Diego Downtown, an IHG Hotel
2.5 star property
8.2 out of 10, Very Good, (1010)
"Breakfast was amazing "
The price is ￥22,378
￥25,220 total
includes taxes & fees
May 27 - May 28
Holiday Inn Express San Diego Downtown, an IHG Hotel
Handlery Hotel
Outdoor pool, pool umbrellas, sun loungers
Handlery Hotel
3.5 star property
7.8 out of 10, Good, (1568)
"I was in a quiet area."
The price is ￥20,096
￥22,647 total
includes taxes & fees
May 14 - May 15
Handlery Hotel
Sheraton Mission Valley San Diego Hotel
Bar (on property)
Sheraton Mission Valley San Diego Hotel
4.0 star property
8.4 out of 10, Very Good, (1106)
"Great overall experience. "
The price is ￥19,488
￥21,962 total
includes taxes & fees
May 27 - May 28
Sheraton Mission Valley San Diego Hotel
Lamplighter Inn & Suites at SDSU
Outdoor pool, pool umbrellas, sun loungers
Lamplighter Inn & Suites at SDSU
2.5 star property
8.8 out of 10, Excellent, (1013)
"Very nice stay for 2 nights. The breakfast options were great and the front desk staff was very pleasant and extremely nice to let us exhausted travelers check in 2 hours early!"
The price is ￥27,240
￥30,100 total
includes taxes & fees
May 13 - May 14
Lamplighter Inn & Suites at SDSU
Springhill Suites San Diego Downtown/Bayfront
Exterior
Springhill Suites San Diego Downtown/Bayfront
3.5 star property
9.2 out of 10, Wonderful, (1001)
"Clean, beautiful property right in the waterfront and close to many San Diego attractions. Parking is expensive in this area but reasonable and easy at this hotel. Centrally located with easy access either walkable or train ride to the marina, little Italy, and gas lamp district. Breakfast was good quality with lots of options. The front desk staff were very nice, and were able to accommodate a late check out which was nice for our overnight stay. "
The price is ￥32,402
￥36,530 total
includes taxes & fees
May 27 - May 28
Springhill Suites San Diego Downtown/Bayfront
Four Points by Sheraton San Diego Downtown Little Italy
Aerial view
Four Points by Sheraton San Diego Downtown Little Italy
3.0 star property
7.0 out of 10, Good, (1001)
"Very comfortable "
The price is ￥24,769
￥27,914 total
includes taxes & fees
May 13 - May 14
Four Points by Sheraton San Diego Downtown Little Italy
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Serra Mesa

Hotels in top San Diego neighborhoods Learn more about Serra Mesa
US Grant Hotel

Downtown San Diego

2 out of top 10 points of interest in this area
4.5/5(8,497 area reviews)

Petco Park and USS Midway Museum are a few top attractions in Downtown San Diego. Hop around the city on the metro at Civic Center Station or Civic Center Station and check out the area's fantastic nightlife, fascinating museums, and beautiful waterfront views.

Find hotels in Downtown San Diego

Serra Mesa hotels information

Number of reviews
30,385
Accommodation
8,475 hotels
Lowest Price
￥13,903
Highest Price
￥43,035

Frequently asked questions

What's it like in Serra Mesa?

Guests are sure to enjoy their time checking out all that San Diego's Serra Mesa neighborhood has to offer. Consider a visit to Stadium Golf Center & Batting Cages as part of your Serra Mesa travel plans.

Where is the best place to stay in Serra Mesa?

For your stay in Serra Mesa, Cozy 2 bedroom unit with pool is one of the top choices based on our traveler data. Other good choices for your stay in the area include Centrally Located San Diego Condo w/Hot Tub & Pool and Central location - 3br/2ba. Stay weekly. Clean, safe, quiet. .

How many hotels will I be able to find in the Serra Mesa area?

Expedia has 29 hotels and other accommodations in Serra Mesa to choose from, making this an ideal home base for exploring the greater San Diego area.

If I need to cancel my hotel reservation in Serra Mesa, will I receive a refund?

Yes, you'll find most hotel reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to view the top deals on offer in Serra Mesa.

Where can I learn more about changing or cancelling my trip to Serra Mesa?

For more information about picking new dates or cancelling your trip to Serra Mesa, click here.

What can I see and do in this San Diego neighborhood?

Stadium Golf Center & Batting Cages is an attraction you might want to check out while you're in Serra Mesa. When you're sightseeing in San Diego, Convoy District and Old Cactus Garden are also worth a stop.

Recent reviews of Serra Mesa hotels

Paradise Point Resort & Spa

Paradise Point Resort & Spa

5/5 Excellent
"Access to the beach "
A verified traveler stayed at Paradise Point Resort & Spa
Posted 2 hours ago
Paradise Point Resort & Spa