What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on our traveler data, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is one of the top choices for your stay in Otay Mesa. This hotel offers free breakfast and an outdoor pool.

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/ .

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Top Otay Mesa Hotels

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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

Veronica

￥25,105 total

includes taxes & fees

Sep 7 - Sep 8

2. Quality Suites San Diego Otay Mesa

Otay Mesa

Mia

￥19,245 total

includes taxes & fees

Sep 20 - Sep 21

3. Best Western Americana Inn

8 km from Otay Mesa

Luis

￥20,503 total

includes taxes & fees

Sep 20 - Sep 21

4. Ayres Hotel San Diego South - Chula Vista

6.5 km from Otay Mesa

Shan Shan

￥30,549 total

includes taxes & fees

Sep 20 - Sep 21

Premium bedding, in-room safe, desk, laptop workspace

5. Best Western Plus Marina Gateway Hotel

16.9 km from Otay Mesa

Samuel

￥26,070 total

includes taxes & fees

Sep 7 - Sep 8

6. Comfort Inn Chula Vista San Diego South

13 km from Otay Mesa

Katsuya

￥18,271 total

includes taxes & fees

Oct 4 - Oct 5

7. La Quinta Inn by Wyndham San Diego Chula Vista

12.9 km from Otay Mesa

Sharon

￥18,557 total

includes taxes & fees

Sep 13 - Sep 14

8. Holiday Inn Express San Diego South - Chula Vista by IHG

14.5 km from Otay Mesa

Cathie

￥25,091 total

includes taxes & fees

Sep 7 - Sep 8

9. SpringHill Suites by Marriott Chula Vista Eastlake

10.5 km from Otay Mesa

Alfonso

￥34,459 total

includes taxes & fees

Sep 27 - Sep 28

10. The Rambler Hotel

14.8 km from Otay Mesa

Tracy

￥22,963 total

includes taxes & fees

Sep 17 - Sep 18

Standard Single Room, 1 King Bed, Non Smoking | Desk, blackout drapes, iron/ironing board (on request), WiFi (free)

11. Hotel Palmeras Chula Vista

14.4 km from Otay Mesa

Idanesha

￥12,379 total

includes taxes & fees

Oct 4 - Oct 5

12. Hercor Hotel - Urban Boutique

13.6 km from Otay Mesa

Mahmoud

￥17,314 total

includes taxes & fees

Sep 20 - Sep 21

Blackout drapes, iron/ironing board (on request), cribs (free)

13. Howard Johnson by Wyndham National City/San Diego South

18.3 km from Otay Mesa

Erika

￥13,384 total

includes taxes & fees

Oct 4 - Oct 5

14. Hampton Inn & Suites San Diego Airport Liberty Station

29.2 km from Otay Mesa

David

￥34,140 total

includes taxes & fees

Sep 7 - Sep 8

15. Motel 6 El Cajon, CA - San Diego

27 km from Otay Mesa

Melissa

￥12,634 total

includes taxes & fees

Sep 23 - Sep 24

16. WoodSpring Suites Santee - San Diego Northeast

30.9 km from Otay Mesa

Adan

￥17,291 total

includes taxes & fees

Sep 6 - Sep 7

17. Best Western Seven Seas

28.7 km from Otay Mesa

Colleen

￥15,440 total

includes taxes & fees

Sep 7 - Sep 8

18. Lamplighter Inn & Suites at SDSU

24.4 km from Otay Mesa

Bernadette

￥23,653 total

includes taxes & fees

Sep 28 - Sep 29

19. Wyndham Garden San Diego Near SeaWorld

31.3 km from Otay Mesa

Nayla

￥16,507 total

includes taxes & fees

Sep 10 - Sep 11

20. Kings Inn San Diego

29.1 km from Otay Mesa

Manuel

￥16,343 total

includes taxes & fees

Sep 7 - Sep 8

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Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa

A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

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A beach with surfers and swimmers during sunset.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

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A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

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Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

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An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

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Top Otay Mesa Hotel Reviews

Hard Rock Hotel San Diego

10/10 Excellent

"Great experience!"

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

10/10 Excellent

"Very clean room, comfortable beds, and a variety of selections in the breakfast buffet. We had trouble with the TV and staff came right up and assisted and got it up and going. I wish I would have realized how close the Mexico border was, we would have brought our passports to go shopping. There are many food choices less than a block away"

Find hotels in Otay Mesa, San Diego

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Otay Mesa hotels

1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

2. Quality Suites San Diego Otay Mesa

3. Best Western Americana Inn

4. Ayres Hotel San Diego South - Chula Vista

5. Best Western Plus Marina Gateway Hotel

6. Comfort Inn Chula Vista San Diego South

7. La Quinta Inn by Wyndham San Diego Chula Vista

8. Holiday Inn Express San Diego South - Chula Vista by IHG

9. SpringHill Suites by Marriott Chula Vista Eastlake

10. The Rambler Hotel

11. Hotel Palmeras Chula Vista

12. Hercor Hotel - Urban Boutique

13. Howard Johnson by Wyndham National City/San Diego South

14. Hampton Inn & Suites San Diego Airport Liberty Station

15. Motel 6 El Cajon, CA - San Diego

16. WoodSpring Suites Santee - San Diego Northeast

17. Best Western Seven Seas

18. Lamplighter Inn & Suites at SDSU

19. Wyndham Garden San Diego Near SeaWorld

20. Kings Inn San Diego

Where to stay in Otay Mesa

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Otay Mesa Hotel Reviews

Hard Rock Hotel San Diego

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