What's it like in Otay Mesa?

Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.

Where is the best hotel for a stay in Otay Mesa?

Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa .

If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.

Where can I learn more about changing or cancelling my trip to Otay Mesa?

To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/ .

What is there to do in this San Diego neighborhood?

A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

Top Otay Mesa Hotels

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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Otay Mesa

rosita

￥23,474 total

includes taxes & fees

Jun 7 - Jun 8

Quality Suites San Diego Otay Mesa

Otay Mesa

Mikael

￥19,377 total

includes taxes & fees

May 25 - May 26

Premium bedding, in-room safe, desk, laptop workspace

Best Western Plus Marina Gateway Hotel

16.9 km from Otay Mesa

Ines

￥26,079 total

includes taxes & fees

May 20 - May 21

Best Western Americana Inn

8 km from Otay Mesa

Nancy

￥22,087 total

includes taxes & fees

Jun 4 - Jun 5

Hampton Inn & Suites Imperial Beach San Diego

13.7 km from Otay Mesa

Catherine A

￥27,108 total

includes taxes & fees

May 25 - May 26

Outdoor pool, open 9:00 AM to 5:00 PM, cabanas (surcharge)

Sycuan Casino Resort

28.5 km from Otay Mesa

Tugba

￥19,122 total

includes taxes & fees

May 26 - May 27

Lafayette Hotel & Club

26.8 km from Otay Mesa

Kristi

￥45,461 total

includes taxes & fees

May 21 - May 22

Ayres Hotel San Diego South - Chula Vista

6.5 km from Otay Mesa

Giselle

￥32,904 total

includes taxes & fees

Jun 7 - Jun 8

Holiday Inn Express San Diego South - Chula Vista by IHG

14.5 km from Otay Mesa

Lingzhi

￥23,613 total

includes taxes & fees

May 25 - May 26

Sheraton San Diego Resort

28.1 km from Otay Mesa

Emily

￥30,854 total

includes taxes & fees

May 25 - May 26

Comfort Inn Chula Vista San Diego South

13 km from Otay Mesa

Megan

￥18,229 total

includes taxes & fees

Jun 14 - Jun 15

La Quinta Inn by Wyndham San Diego Chula Vista

12.9 km from Otay Mesa

Helda

￥18,712 total

includes taxes & fees

May 25 - May 26

SpringHill Suites by Marriott Chula Vista Eastlake

10.5 km from Otay Mesa

Nicholas

￥37,479 total

includes taxes & fees

May 31 - Jun 1

Motel 6 El Cajon, CA - San Diego

27 km from Otay Mesa

Jamilett

￥14,935 total

includes taxes & fees

May 21 - May 22

Hampton Inn & Suites San Diego Airport Liberty Station

29.2 km from Otay Mesa

Mercyditha De

￥32,773 total

includes taxes & fees

May 31 - Jun 1

Studio 6 Suites San Ysidro, CA -San Diego South Bay

6.9 km from Otay Mesa

Erik

￥13,753 total

includes taxes & fees

May 20 - May 21

TownePlace Suites by Marriott San Diego Airport/Liberty Station

29.3 km from Otay Mesa

Derek

￥33,209 total

includes taxes & fees

May 26 - May 27

Best Western Plus La Mesa San Diego

24.6 km from Otay Mesa

Sergio

￥24,341 total

includes taxes & fees

May 26 - May 27

Holiday Inn Express San Diego Airport - Old Town by IHG

28.8 km from Otay Mesa

Amelia

￥25,742 total

includes taxes & fees

May 25 - May 26

Outdoor pool, open 7:00 AM to 10:00 PM, cabanas (surcharge)

San Diego Mission Bay Resort

Mission Bay, 33.1 km from Otay Mesa

Krystal

￥46,555 total

includes taxes & fees

May 20 - May 21

View all properties

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

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Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

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Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

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Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

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Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

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Top Otay Mesa Hotel Reviews

The Sofia Hotel

10/10 Excellent

"The Sophia was an awesome quaint hotel. It had all the amenities. Our room had a street view and in the distance you could see the beach. I wish we would’ve stayed more than one night. Definitely looking forward to staying here again. !"

Lafayette Hotel & Club

8/10 Good

"This is a very unique property that does many things well, but still has room for some improvements. Pros: Incredible interior design. Every space is beautifully done, very unique with high end finishes and makes you feel like you’ve gone back in time. Food and drinks are delicious at all spots. Staff is very kind and as helpful. Valet parking was easy and they got our car relatively fast even during busy times Lively atmosphere (also a con) Cons: 1st one is us specifically, I don’t know what went wrong but we booked a balcony room poolside but they gave us a ground level poolside. This is technically an upgrade monetarily, but to us it kind of put a damper to the stay. I specifically booked a balcony because I wanted to be close to the action but still be able to remove myself. Our room was in the corner and people kept seating in our outdoor seating, one point we were asleep and there were people sitting and drinking/laughing on our seats. I didn’t want to constantly have to ask people to move so most of the time we just let them be. Staff tried to change our room but none were available. The noise is the big con. I knew this was a party hotel going in but I didn’t think it would be that loud in the rooms. Music blasting from the hotel until 2am and then the room above us starting blasting music from 6am. So no sleep Saturday night. You could feel it in your bones. Come during the weekday for chill vibes. Weekend if you don’t mind noise!"

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

10/10 Excellent

"The room was super clean and the bed was comfortable. The water pressure in the shower was lacking. We were on the second floor and it shouldn't of been so low. The breakfast is very nice and lots to choose from! The jacuzzi was nice and clean and perfect for a day after going to SeaWorld. CON: parking is $26 a day and wish we would of used the street parking. Such a ridiculous charge when you're paying to stay there!"

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Our top choices for Otay Mesa hotels

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Quality Suites San Diego Otay Mesa

Best Western Plus Marina Gateway Hotel

Best Western Americana Inn

Hampton Inn & Suites Imperial Beach San Diego

Sycuan Casino Resort

Lafayette Hotel & Club

Ayres Hotel San Diego South - Chula Vista

Holiday Inn Express San Diego South - Chula Vista by IHG

Sheraton San Diego Resort

Comfort Inn Chula Vista San Diego South

La Quinta Inn by Wyndham San Diego Chula Vista

SpringHill Suites by Marriott Chula Vista Eastlake

Motel 6 El Cajon, CA - San Diego

Hampton Inn & Suites San Diego Airport Liberty Station

Studio 6 Suites San Ysidro, CA -San Diego South Bay

TownePlace Suites by Marriott San Diego Airport/Liberty Station

Best Western Plus La Mesa San Diego

Holiday Inn Express San Diego Airport - Old Town by IHG

San Diego Mission Bay Resort

Where to stay in Otay Mesa

Downtown San Diego

Pacific Beach

Mission Beach

Gaslamp Quarter

Mission Bay

Top Otay Mesa Hotel Reviews

The Sofia Hotel

Frequently asked questions

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