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Our top choices for Otay Mesa hotels

Quality Suites San Diego Otay Mesa

Quality Suites San Diego Otay Mesa
2.5 star property
Otay Mesa
7.0 out of 10, Good, (1,007 reviews)
"Great staff.. location close to the airport!"
United States
Vivian
The price is ¥16,873
¥19,193 total
includes taxes & fees
Apr 26 - Apr 27
Quality Suites San Diego Otay Mesa

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
2.5 star property
Otay Mesa
8.0 out of 10, Very Good, (1,678 reviews)
"Great breakfast!"
United States
Susan
The price is ¥18,730
¥21,306 total
includes taxes & fees
Apr 6 - Apr 7
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
28.1 km from Otay Mesa
8.4 out of 10, Very Good, (3,405 reviews)
"Nice hotel with great location "
United States
DIANA
The price is ¥23,333
¥33,803 total
includes taxes & fees
Apr 12 - Apr 13
Sheraton San Diego Resort

Valli Hi Motel

Valli Hi Motel
2.5 star property
7.9 km from Otay Mesa
8.4 out of 10, Very Good, (1,011 reviews)
"Great location, near shops, restaurants and beaches. "
United States
Miguelina
The price is ¥11,293
¥12,867 total
includes taxes & fees
Apr 5 - Apr 6
Valli Hi Motel

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
26.8 km from Otay Mesa
9.2 out of 10, Wonderful, (1,557 reviews)
"Everything about that stay was perfect"
United States
Victoria
The price is ¥39,524
¥45,430 total
includes taxes & fees
Apr 6 - Apr 7
Lafayette Hotel & Club

Sycuan Casino Resort

Sycuan Casino Resort
4.0 star property
28.5 km from Otay Mesa
9.2 out of 10, Wonderful, (1,808 reviews)
"Awesome place "
United States
Jonathan
The price is ¥11,603
¥14,668 total
includes taxes & fees
Apr 5 - Apr 6
Sycuan Casino Resort

Best Western San Diego Pacific Beach/Mission Bay

Best Western San Diego Pacific Beach/Mission Bay
2.5 star property
Bay Park, 33.6 km from Otay Mesa
8.2 out of 10, Very Good, (326 reviews)
"Nice staff and good breakfast."
United States
Carol
The price is ¥17,321
¥19,909 total
includes taxes & fees
Apr 12 - Apr 13
Best Western San Diego Pacific Beach/Mission Bay

SpringHill Suites by Marriott Chula Vista Eastlake

SpringHill Suites by Marriott Chula Vista Eastlake
3.5 star property
10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (611 reviews)
"By far, one of the best hotels we have stayed at! Very clean, friendly and knowledgeable front desk staff, amenities galore and right across the street from family friendly entertainment venues like play city and ninja factory. The pool was amazing - we had all a great time! "
United States
Daniel
The price is ¥27,328
¥30,114 total
includes taxes & fees
Apr 19 - Apr 20
SpringHill Suites by Marriott Chula Vista Eastlake

Ocean Villa Inn

Ocean Villa Inn
2.5 star property
Ocean Beach, 33.7 km from Otay Mesa
8.0 out of 10, Very Good, (1,208 reviews)
"Amazing def will stay again "
United States
Tanya
The price is ¥20,443
¥23,049 total
includes taxes & fees
Apr 2 - Apr 3
Ocean Villa Inn

Studio 6 Suites San Ysidro, CA -San Diego South Bay

Studio 6 Suites San Ysidro, CA -San Diego South Bay
2.5 star property
6.9 km from Otay Mesa
8.0 out of 10, Very Good, (1,561 reviews)
"Good location"
United States
Joshua
The price is ¥12,682
¥14,450 total
includes taxes & fees
Apr 15 - Apr 16
Studio 6 Suites San Ysidro, CA -San Diego South Bay

Cherokee Lodge

Cherokee Lodge
2.5 star property
24 km from Otay Mesa
9.4 out of 10, Exceptional, (867 reviews)
"Hidden Gem. "
United States
Jennifer
The price is ¥26,825
¥29,508 total
includes taxes & fees
Apr 2 - Apr 3
Cherokee Lodge

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
31.3 km from Otay Mesa
7.4 out of 10, Good, (4,201 reviews)
"great place"
Canada
souheil
The price is ¥17,000
¥19,541 total
includes taxes & fees
Apr 6 - Apr 7
Wyndham Garden San Diego Near SeaWorld

Best Western Americana Inn

Best Western Americana Inn
2.5 star property
8 km from Otay Mesa
9.0 out of 10, Wonderful, (1,245 reviews)
"Great place and service. Will definitely stay there again. "
United States
Maria
The price is ¥19,416
¥22,085 total
includes taxes & fees
Apr 12 - Apr 13
Best Western Americana Inn

Bahia Resort Hotel

Bahia Resort Hotel
3.5 star property
Central Mission Beach, 34.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,951 reviews)
"We stay here a few times a year normally and love the location. "
United States
Lindsay
The price is ¥31,987
¥45,582 total
includes taxes & fees
Apr 12 - Apr 13
Bahia Resort Hotel

Best Western Plus Marina Gateway Hotel

Best Western Plus Marina Gateway Hotel
3.5 star property
16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,751 reviews)
"Great hotel"
United States
Deante
The price is ¥25,238
¥27,811 total
includes taxes & fees
Apr 5 - Apr 6
Best Western Plus Marina Gateway Hotel

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
24.4 km from Otay Mesa
9.2 out of 10, Wonderful, (2,065 reviews)
"good atmosphere, good staff, friendly staff, good food, pool is amazing, restaurants are affordable and excellent."
United States
Artsrun
The price is ¥34,998
¥48,150 total
includes taxes & fees
Apr 2 - Apr 3
Marriott Marquis San Diego Marina

El Cordova Hotel on Coronado Island

El Cordova Hotel on Coronado Island
3.5 star property
23.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,002 reviews)
"Best hotel i have stayed"
United States
araceli
The price is ¥27,379
¥34,933 total
includes taxes & fees
Apr 26 - Apr 27
El Cordova Hotel on Coronado Island

Heritage Inn San Diego

Heritage Inn San Diego
2.0 star property
31.8 km from Otay Mesa
7.4 out of 10, Good, (1,348 reviews)
"Great and easy way to check in and out!"
United States
Pedro
The price is ¥11,063
¥12,716 total
includes taxes & fees
Apr 26 - Apr 27
Heritage Inn San Diego

Ocean Beach Hotel

Ocean Beach Hotel
3.0 star property
Ocean Beach, 33.5 km from Otay Mesa
8.8 out of 10, Excellent, (1,294 reviews)
"Cute place, easy location & staff was so friendly. "
United States
Ericka A
The price is ¥23,870
¥26,913 total
includes taxes & fees
Apr 13 - Apr 14
Ocean Beach Hotel

Courtyard by Marriott San Diego Airport/Liberty Station

Courtyard by Marriott San Diego Airport/Liberty Station
3.0 star property
29.7 km from Otay Mesa
9.2 out of 10, Wonderful, (1,306 reviews)
"Great hotel"
United States
Amy
The price is ¥29,525
¥33,938 total
includes taxes & fees
Apr 5 - Apr 6
Courtyard by Marriott San Diego Airport/Liberty Station
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Otay Mesa

Find the best Otay Mesa areas and neighborhoods for the activities you enjoy most. Learn more about Otay Mesa
Learn more about Otay Mesa

Downtown San Diego

Cultural and financial hub, Downtown San Diego boasts the Symphony, Opera, theaters, museums, and historic sites like Gaslamp Quarter. Enjoy diverse shops, dining, nightlife, and convenient public transport options.

Pacific Beach

Boasting a lively nightlife scene, Pacific Beach offers miles of sandy shores, a bustling 3.2-mile boardwalk, and attractions like Crystal Pier and Kate Sessions Park. Enjoy local shops, bars, and eateries along the vibrant walkway.

Mission Beach

Spanning nearly two miles of oceanfront, this sandbar community offers sunbathing, surfing, and beach volleyball, with nearby attractions like Belmont Park's Giant Dipper Roller Coaster and SeaWorld in Mission Bay Park.

Gaslamp Quarter

Downtown San Diego's historic district boasts Victorian-era buildings, now housing vibrant restaurants, shops, and entertainment venues. Stroll from Broadway to Harbor Drive, and 4th to 6th Avenue, admiring the newly installed gaslamps at Market Street.

Ocean Beach

Ocean Beach is known for its stunning beaches, and with sights like Dog Beach and Sunset Cliffs Natural Park, you won't get bored spending a day wandering around this part of San Diego.

Top Otay Mesa Hotel Reviews

Frequently asked questions

What's it like in Otay Mesa?
Otay Mesa is a neighborhood that travelers like for its beaches, restaurants, and shopping.
Where is the best hotel for a stay in Otay Mesa?
Based on Expedia customer reviews, Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG is the highest ranked property in Otay Mesa. This hotel offers free breakfast and an outdoor pool. Another top choice in the area is Quality Suites San Diego Otay Mesa.
If I need to cancel my hotel reservation in Otay Mesa, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Otay Mesa.
Where can I learn more about changing or cancelling my trip to Otay Mesa?
To find more details about changing or cancelling your trip to Otay Mesa, go to https://www.expedia.com/service/.
What is there to do in this San Diego neighborhood?
A few places to visit in the area around Otay Mesa include High Performance Center in Tijuana, Parque Industrial FINSA Tijuana, and Otay Sports Fields. While you're out sightseeing, Caliente Casino and Alameda Otay are a couple of additional sights to visit in San Diego.

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