What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favorite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N .

How many hotels will I find in the Downtown South San Francisco area?

When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page .

What can I see and do in this South San Francisco neighborhood?

South San Francisco Hillside Sign, Sign Hill Park, and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.

Top Downtown South San Francisco Hotels

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco

Alma

￥21,178 total

includes taxes & fees

Apr 3 - Apr 4

Airport Inn

Downtown South San Francisco

Ronald

￥16,794 total

includes taxes & fees

Apr 19 - Apr 20

Deluxe Room | 1 bedroom, individually decorated, individually furnished, desk

Miller Apartments

Downtown South San Francisco

Kasey

￥21,112 total

includes taxes & fees

Mar 27 - Mar 28

Premium bedding, pillowtop beds, in-room safe, desk

Inn By The SFO

Downtown South San Francisco

carlos

Aloft San Francisco Airport

6.9 km from Downtown South San Francisco

Mark

￥21,551 total

includes taxes & fees

Apr 25 - Apr 26

Hotel Riu Plaza Fisherman's Wharf

16.8 km from Downtown South San Francisco

Alexis

￥33,623 total

includes taxes & fees

Apr 12 - Apr 13

The Westin San Francisco Airport

6.9 km from Downtown South San Francisco

Hitomi

￥36,689 total

includes taxes & fees

Apr 25 - Apr 26

The Marina Inn on San Francisco Bay

20.5 km from Downtown South San Francisco

Walkiria

￥15,761 total

includes taxes & fees

Mar 29 - Mar 30

DoubleTree by Hilton San Francisco Airport

9.3 km from Downtown South San Francisco

Fritz Lou

￥20,317 total

includes taxes & fees

Apr 11 - Apr 12

The Dylan at SFO

7.1 km from Downtown South San Francisco

Aurora

￥21,569 total

includes taxes & fees

Mar 28 - Mar 29

Hotel Zephyr San Francisco

16.8 km from Downtown South San Francisco

Ramona

￥34,953 total

includes taxes & fees

Mar 30 - Mar 31

Vagabond Inn Executive San Francisco Airport

7.6 km from Downtown South San Francisco

Justina

￥17,708 total

includes taxes & fees

Apr 10 - Apr 11

1 Bedroom Suite, 1 King Bed | Living area | Flat-screen TV

Cow Hollow Inn & Suites

16 km from Downtown South San Francisco

Elizabeth

￥22,201 total

includes taxes & fees

Mar 29 - Mar 30

Hotel Aura SFO

4.4 km from Downtown South San Francisco

Allyson

￥19,641 total

includes taxes & fees

Apr 12 - Apr 13

Hyatt Place San Francisco Downtown

13.7 km from Downtown South San Francisco

Lauren

￥37,166 total

includes taxes & fees

Mar 29 - Mar 30

Hotel Aluxor SFO

3.7 km from Downtown South San Francisco

Daniel

￥20,424 total

includes taxes & fees

Mar 29 - Mar 30

Hampton Inn & Suites Oakland Airport-Alameda

17.1 km from Downtown South San Francisco

Juvy V

￥20,090 total

includes taxes & fees

Apr 24 - Apr 25

Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Hotel Caza Fisherman's Wharf

16.6 km from Downtown South San Francisco

william

￥31,712 total

includes taxes & fees

Apr 14 - Apr 15

Premium bedding, down comforters, desk, iron/ironing board

Marina Village Inn

19.4 km from Downtown South San Francisco

Alannah

￥14,546 total

includes taxes & fees

Apr 2 - Apr 3

LUMA Hotel San Francisco

13.3 km from Downtown South San Francisco

Melissa

￥44,640 total

includes taxes & fees

Mar 29 - Mar 30

View all properties

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

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Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

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Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

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Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

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South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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Top Downtown South San Francisco Hotel Reviews

Hotel Caza Fisherman's Wharf

10/10 Excellent

"This place was great! Close to everything and staff was very friendly. Room was clean and the bed was really comfortable. "

Hotel Julian

8/10 Good

"Hotel was conveniently located about 10-15 min walking to nearest bus stop or cable car. 1 king bed room we stayed had a good size bedroom and bathroom for two people. Location of the AC in the bedroom bothered us since it was installed above the bed with fans pointing towards the bed and it was not possible to redirect the orientation of the fans. We had to run it before bedtime to air the room and then turn it off since it was too loud and cold but then room may get little stuffy. They charge $20 amenities fee which we never heard of in any of our stays in CA. This included breakfast which had tea, coffee and croissants and muffins which were not very fresh but edible. We rather have breakfast not included and not pay for it and choose what to eat ourselves rather than eating the same thing every morning. Staff was very nice. Overall we enjoyed our stay. "

Find hotels in Downtown South San Francisco, San Francisco

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

Airport Inn

Miller Apartments

Inn By The SFO

Aloft San Francisco Airport

Hotel Riu Plaza Fisherman's Wharf

The Westin San Francisco Airport

The Marina Inn on San Francisco Bay

DoubleTree by Hilton San Francisco Airport

The Dylan at SFO

Hotel Zephyr San Francisco

Vagabond Inn Executive San Francisco Airport

Cow Hollow Inn & Suites

Hotel Aura SFO

Hyatt Place San Francisco Downtown

Hotel Aluxor SFO

Hampton Inn & Suites Oakland Airport-Alameda

Hotel Caza Fisherman's Wharf

Marina Village Inn

LUMA Hotel San Francisco

Where to stay in Downtown South San Francisco

Union Square

Fisherman's Wharf

Downtown San Francisco

Nob Hill

South of Market

Top Downtown South San Francisco Hotel Reviews

Hotel Caza Fisherman's Wharf

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