What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, Inn By The SFO is a highly ranked property in Downtown South San Francisco. This hotel offers free parking and free WiFi. Other favorite options in the area include Airport Inn and La Quinta Inn & Suites by Wyndham San Francisco Airport N .

How many hotels will I find in the Downtown South San Francisco area?

When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page .

What can I see and do in this South San Francisco neighborhood?

South San Francisco Hillside Sign, Sign Hill Park, and See's Candies are just a few of the places to visit in and around Downtown South San Francisco. Cinemark Century at Tanforan and K1 Speed are also worth a visit when you're out sightseeing in South San Francisco.

Top Downtown South San Francisco Hotels

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Our top choices for Downtown South San Francisco hotels

La Quinta Inn & Suites by Wyndham San Francisco Airport N

Downtown South San Francisco

Raul

￥21,084 total

includes taxes & fees

Mar 30 - Mar 31

Airport Inn

Downtown South San Francisco

Ronald

￥16,755 total

includes taxes & fees

Mar 27 - Mar 28

Deluxe Room | 1 bedroom, individually decorated, individually furnished, desk

Miller Apartments

Downtown South San Francisco

Kasey

￥21,680 total

includes taxes & fees

Mar 30 - Mar 31

Premium bedding, pillowtop beds, in-room safe, desk

Inn By The SFO

Downtown South San Francisco

Kelly

Aloft San Francisco Airport

6.9 km from Downtown South San Francisco

Mark

￥18,405 total

includes taxes & fees

Apr 4 - Apr 5

Hotel Riu Plaza Fisherman's Wharf

16.8 km from Downtown South San Francisco

Alexis

￥33,937 total

includes taxes & fees

Apr 12 - Apr 13

The Westin San Francisco Airport

6.9 km from Downtown South San Francisco

Lucila

￥27,809 total

includes taxes & fees

Apr 4 - Apr 5

The Marina Inn on San Francisco Bay

20.5 km from Downtown South San Francisco

ILiana

￥16,079 total

includes taxes & fees

Mar 29 - Mar 30

DoubleTree by Hilton San Francisco Airport

9.3 km from Downtown South San Francisco

Fritz Lou

￥17,563 total

includes taxes & fees

Apr 4 - Apr 5

The Dylan at SFO

7.1 km from Downtown South San Francisco

Robert

￥21,516 total

includes taxes & fees

Mar 28 - Mar 29

Hotel Zephyr San Francisco

16.8 km from Downtown South San Francisco

Ramona

￥35,473 total

includes taxes & fees

Apr 12 - Apr 13

Vagabond Inn Executive San Francisco Airport

7.6 km from Downtown South San Francisco

Shaquille

￥19,131 total

includes taxes & fees

Mar 27 - Mar 28

1 Bedroom Suite, 1 King Bed | Living area | Flat-screen TV

Cow Hollow Inn & Suites

16 km from Downtown South San Francisco

Elizabeth

Hotel Aura SFO

4.4 km from Downtown South San Francisco

Richard

￥19,593 total

includes taxes & fees

Apr 12 - Apr 13

Hyatt Place San Francisco Downtown

13.7 km from Downtown South San Francisco

Courtney

￥37,075 total

includes taxes & fees

Mar 29 - Mar 30

Hotel Aluxor SFO

3.7 km from Downtown South San Francisco

Arloene

￥20,373 total

includes taxes & fees

Mar 29 - Mar 30

Hampton Inn & Suites Oakland Airport-Alameda

17.1 km from Downtown South San Francisco

Darcy

￥20,034 total

includes taxes & fees

Apr 24 - Apr 25

Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds

Hotel Caza Fisherman's Wharf

16.6 km from Downtown South San Francisco

Shawn

￥31,633 total

includes taxes & fees

Apr 12 - Apr 13

Premium bedding, down comforters, desk, iron/ironing board

Marina Village Inn

19.4 km from Downtown South San Francisco

Alannah

￥14,509 total

includes taxes & fees

Apr 1 - Apr 2

LUMA Hotel San Francisco

13.3 km from Downtown South San Francisco

Brenda

￥44,530 total

includes taxes & fees

Mar 29 - Mar 30

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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

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Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

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Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

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South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

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Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

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Top Downtown South San Francisco Hotel Reviews

Hotel Riu Plaza Fisherman's Wharf

10/10 Excellent

"Well appointed rooms and very clean and tidy. Excellent breakfast. Good location right at Fisherman's Wharf. Views were limited, but the rooms were light and airy."