Find hotels in Downtown South San Francisco, San Francisco from ￥14,299

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Sep 27 - Sep 28
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Discover 4,606 Downtown South San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Exterior

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
8.0 out of 10, Very Good, (2036)
"Great place to stay "
The price is ￥16,137
￥18,928 total
includes taxes & fees
Oct 26 - Oct 27
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Airport Inn
Interior detail

Airport Inn

2.0 star property
8.8 out of 10, Excellent, (958)
"The inside is super nice and clean. Very pleasant"
The price is ￥13,616
￥15,998 total
includes taxes & fees
Oct 11 - Oct 12
Airport Inn
Inn By The SFO
Lobby

Inn By The SFO

2.0 star property
7.8 out of 10, Good, (1000)
"Excellent property!!! I would definitely recommend!!! Great stay!!! "
Inn By The SFO
Miller Apartments
Fridge, microwave, coffee/tea maker, dining tables

Miller Apartments

2.0 star property
7.8 out of 10, Good, (14)
"Ty"
The price is ￥9,343
￥22,245 total
includes taxes & fees
Sep 29 - Sep 30
Miller Apartments
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Free daily buffet breakfast

Holiday Inn Express and Suites Fisherman's Wharf by IHG

3.0 star property
9.2 out of 10, Wonderful, (2177)
"Good place to stay!"
The price is ￥20,666
￥28,817 total
includes taxes & fees
Oct 19 - Oct 20
Holiday Inn Express and Suites Fisherman's Wharf by IHG
Hotel North Beach
Lobby

Hotel North Beach

2.0 star property
7.0 out of 10, Good, (1008)
"Good location "
Hotel North Beach
Half Moon Bay Lodge
Exterior

Half Moon Bay Lodge

3.0 star property
9.0 out of 10, Wonderful, (1005)
"Beautiful landscaping surrounding area and close to beaches. "
The price is ￥24,630
￥28,858 total
includes taxes & fees
Oct 7 - Oct 8
Half Moon Bay Lodge
Hyatt Centric Fisherman's Wharf San Francisco
Terrace/patio

Hyatt Centric Fisherman's Wharf San Francisco

4.0 star property
8.6 out of 10, Excellent, (1428)
"Great place to stay."
The price is ￥24,815
￥35,365 total
includes taxes & fees
Oct 17 - Oct 18
Hyatt Centric Fisherman's Wharf San Francisco
Hotel Caza Fisherman's Wharf
Exterior

Hotel Caza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (3811)
"very nice place to stay"
The price is ￥25,428
￥36,790 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Caza Fisherman's Wharf
Hotel Riu Plaza Fisherman's Wharf
Lobby sitting area

Hotel Riu Plaza Fisherman's Wharf

4.0 star property
9.0 out of 10, Wonderful, (6911)
"It was very close to tourist points, breakfast was superb!"
The price is ￥22,564
￥32,715 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Riu Plaza Fisherman's Wharf
FOUND Hotel Carlton, Nob Hill
Front of property

FOUND Hotel Carlton, Nob Hill

2.0 star property
8.6 out of 10, Excellent, (916)
"Easy check in and check out and nice rooms "
The price is ￥12,149
￥14,299 total
includes taxes & fees
Oct 20 - Oct 21
FOUND Hotel Carlton, Nob Hill
The Lodge at Tiburon
Front of property

The Lodge at Tiburon

3.5 star property
8.8 out of 10, Excellent, (1018)
"Overall a great stay. "
The price is ￥31,640
￥39,691 total
includes taxes & fees
Sep 28 - Sep 29
The Lodge at Tiburon
Hotel Majestic
Front of property

Hotel Majestic

3.5 star property
9.2 out of 10, Wonderful, (1031)
"Nice, nostalgic hotel. Would definitely stay there again. "
The price is ￥17,698
￥20,619 total
includes taxes & fees
Oct 20 - Oct 21
Hotel Majestic
The Marina Inn on San Francisco Bay
Outdoor pool

The Marina Inn on San Francisco Bay

2.5 star property
8.6 out of 10, Excellent, (2139)
"What a great little gem for the Bay!"
The price is ￥14,559
￥16,597 total
includes taxes & fees
Sep 28 - Sep 29
The Marina Inn on San Francisco Bay
Hotel Nikko San Francisco
Front of property - evening/night

Hotel Nikko San Francisco

4.5 star property
9.4 out of 10, Exceptional, (2587)
"Everything from the staff to the location was excellent. Will definitely stay here again."
The price is ￥31,640
￥44,114 total
includes taxes & fees
Oct 2 - Oct 3
Hotel Nikko San Francisco
Hotel Zephyr San Francisco
Game room

Hotel Zephyr San Francisco

4.0 star property
8.6 out of 10, Excellent, (2235)
"Great hotel! Really close to Pier 39 and the customer service was fantastic. "
The price is ￥21,489
￥30,581 total
includes taxes & fees
Oct 17 - Oct 18
Hotel Zephyr San Francisco
SFO El Rancho Inn SureStay Collection by Best Western
Exterior

SFO El Rancho Inn SureStay Collection by Best Western

3.0 star property
8.4 out of 10, Very Good, (2865)
"Very clean, staff was very helpful and the location is perfect. "
The price is ￥17,152
￥19,844 total
includes taxes & fees
Oct 4 - Oct 5
SFO El Rancho Inn SureStay Collection by Best Western
Hyatt Regency San Francisco Airport
Exterior

Hyatt Regency San Francisco Airport

4.0 star property
8.8 out of 10, Excellent, (1318)
"The location was great"
The price is ￥19,314
￥25,846 total
includes taxes & fees
Sep 28 - Sep 29
Hyatt Regency San Francisco Airport
Hotel Skye SFO
Standard Room, Multiple Beds | In-room safe, desk, laptop workspace, iron/ironing board

Hotel Skye SFO

3.0 star property
8.8 out of 10, Excellent, (1454)
"Great property, friendly staff and close to airport."
The price is ￥16,010
￥19,229 total
includes taxes & fees
Sep 29 - Sep 30
Hotel Skye SFO
The Dylan at SFO
Lobby sitting area

The Dylan at SFO

3.0 star property
9.2 out of 10, Wonderful, (1770)
"Sweet small hotel really close to the SFO Airport with lots of nice amenities for an inexpensive hotel!"
The price is ￥47,553
￥55,277 total
includes taxes & fees
Oct 13 - Oct 14
The Dylan at SFO
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most.
Union Square which includes a high rise building and a city

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Fisherman\'s Wharf featuring a bay or harbor

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Downtown San Francisco featuring railway items

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

South of Market featuring skyline, a city and city views

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill showing a city and street scenes

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Downtown South San Francisco Hotel Reviews

Crowne Plaza San Francisco Airport by IHG

Crowne Plaza San Francisco Airport by IHG

10/10 Excellent
"Nice staff. Reliable shuttle to airport. Good bed"
Susan 1-night trip
Posted 12 hours ago
Crowne Plaza San Francisco Airport by IHG

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Downtown South San Francisco?

You'll be sure to have fun visiting South San Francisco's Downtown South San Francisco neighborhood.

What's a favorite place to stay in Downtown South San Francisco?

Based on Expedia customer reviews, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a highly ranked property in Downtown South San Francisco. This hotel offers free breakfast and an outdoor pool. Other favorite options in the area include Airport Inn and Inn By The SFO.

How many hotels will I find in the Downtown South San Francisco area?

When you want to kick up your feet after a day of exploring the sights in South San Francisco, you can choose from 13 Expedia hotels and other accommodations in Downtown South San Francisco.

If I need to cancel my hotel reservation in Downtown South San Francisco, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to get the best deals available in Downtown South San Francisco.

Where can I learn more about changing or cancelling my trip to Downtown South San Francisco?

To find more details about picking new dates or cancelling your trip to Downtown South San Francisco, head over to our customer service page.

What can I see and do in this South San Francisco neighborhood?

See's Candies, Cinemark Century at Tanforan, and K1 Speed San Francisco are just a few of the places to visit in and around Downtown South San Francisco. The Shops at Tanforan and San Bruno Point Park are also worth a visit when you're out sightseeing in South San Francisco.