Downtown South San Francisco Vacations

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  • City view
    Jul 4 - Jul 5

    Stanford Court San Francisco + Flight

    Downtown San Francisco
    1 night
    4.0 star property
    9.0/10 - Wonderful (1,405 reviews)
    "We made a last-minute stop in San Francisco. We really enjoyed the hotel, the convenient parking and location. We will definitely stay here again."
    Reviewed May 26, 2026
    Roundtrip • Los Angeles (LAX) - San Francisco (SFO)
    LAX - SFO • Nonstop SFO - LAX • Nonstop
    ￥57,691
    ￥39,964
    per traveler
    found 1 day ago
    Stanford Court San Francisco
  • Terrace/patio
    Jul 4 - Jul 6

    Bay Landing San Francisco Airport Hotel + Flight

    Ingold - Milldale
    2 nights
    3.0 star property
    9.0/10 - Wonderful (4,859 reviews)
    "Nice hotel near the Airport. Liked the spacious rooms!"
    Reviewed May 26, 2026
    Roundtrip • Los Angeles (LAX) - San Francisco (SFO)
    LAX - SFO • Nonstop SFO - LAX • Nonstop
    ￥66,067
    ￥48,414
    per traveler
    found 1 day ago
    Bay Landing San Francisco Airport Hotel
  • Meeting facility
    Aug 9 - Aug 13

    The Huntington Hotel + Flight

    Downtown San Francisco
    4 nights
    5.0 star property
    9.0/10 - Wonderful (18 reviews)
    Roundtrip • Tokyo (NRT) - San Francisco (SFO)
    NRT - SFO • 1 stop SFO - NRT • 1 stop
    ￥542,523
    ￥414,312
    per traveler
    found 13 hours ago
    The Huntington Hotel
  • Lobby sitting area
    Jul 4 - Jul 5

    The Marker Union Square San Francisco + Flight

    Union Square
    1 night
    4.0 star property
    9.2/10 - Wonderful (1,300 reviews)
    "We enjoyed our quiet room.The staff was very helpful in helping us coordinate our daily excursions.The breakfasts were very tasty with good choices."
    Reviewed May 27, 2026
    Roundtrip • Los Angeles (LAX) - San Francisco (SFO)
    LAX - SFO • Nonstop SFO - LAX • Nonstop
    ￥52,080
    ￥41,441
    per traveler
    found 1 day ago
    The Marker Union Square San Francisco
  • Reception
    Jul 4 - Jul 6

    Hilton Garden Inn San Francisco Arpt North + Flight

    The East Side
    2 nights
    3.0 star property
    8.6/10 - Excellent (1,000 reviews)
    "Nice clean rooms"
    Reviewed May 26, 2026
    Roundtrip • Los Angeles (LAX) - San Francisco (SFO)
    LAX - SFO • Nonstop SFO - LAX • Nonstop
    ￥51,642
    ￥41,152
    per traveler
    found 1 day ago
    Hilton Garden Inn San Francisco Arpt North

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Union Square

Union Square

4/5(5,227 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown South San Francisco Hotel Deals

La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3 out of 5
20 Airport Blvd South San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥18,177 per night from May 31 to Jun 1
￥18,177
￥21,296 total
May 31 - Jun 1
includes taxes & fees
8.2/10 Very Good! (1,988 reviews)
"Good value. Staff was very helpful but I think they were a little understaffed. I was unable to use the free airport shuttle because the driver just went on break and I would have to wait another hour (on top of the 30 minutes I already waited at the airport) to be picked up. Just bad timing I ..."

Reviewed on May 27, 2026

La Quinta Inn & Suites by Wyndham San Francisco Airport N
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥28,509 per night from May 31 to Jun 1
￥28,509
￥40,116 total
May 31 - Jun 1
includes taxes & fees
9/10 Wonderful! (7,466 reviews)
"I don’t have anything bad to say about this hotel.breakfast was good Great location"

Reviewed on May 27, 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥21,341 per night from May 31 to Jun 1
￥21,341
￥25,117 total
May 31 - Jun 1
includes taxes & fees
8.8/10 Excellent! (2,813 reviews)
"Room was tight"

Reviewed on May 27, 2026

Hilton San Francisco Financial District
See all 4,329 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco vacation package cost?
From just . Yes, you read that right. Our Downtown South San Francisco vacation packages are a simple way to make your dollar go further. Combine your favorite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco vacation package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream vacation to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Center, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco vacation?
Travelers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organizing an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia vacation package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco vacation package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco vacation package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Discover the most popular places to visit in Downtown South San Francisco

Golden Gate Park

Golden Gate Park

4.5/5(5,170 reviews)

This beloved park offers relaxation among trees, flowers and wildlife, right in San Francisco’s backyard.

Golden Gate Park
Pier 39

Pier 39

4.5/5(6,904 reviews)

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39
Oracle Park

Oracle Park

4.5/5(1,482 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park

Things to do

Official Alcatraz Island Prison Tour with Free App Audio Packages

Official Alcatraz Inside Prison Tour with Free App Audio Packages

￥12,691
per adult
100% of travellers recommend
Official Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

￥7,688
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco: Skip-the-Line 1-Hour Bay Cruise by Boat

San Francisco Bay Sightseeing Cruise International Narration

￥6,119
per adult
92% of travellers recommend
San Francisco Bay Sightseeing Cruise International Narration
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.