Downtown South San Francisco Vacations from ￥146,956

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The Latest Downtown South San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Price was ￥195,390, price is now ￥146,956 per person
￥146,956
per person
May 1 - May 4
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9/10 Wonderful! (7,092 reviews)
Room clean! Buffet awesome!

Reviewed on Feb 26, 2026

The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Price was ￥231,639, price is now ￥165,728 per person
￥165,728
per person
Apr 30 - May 4
found 24 hours ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (670 reviews)
We had a deluxe king room. The room was small and basic, but sparkly clean and had a very comfortable bed. We really liked the location. It was very central to everything we wanted to do.

Reviewed on Feb 12, 2026

Huntington Hotel

Huntington Hotel

4.5 out of 5
Downtown San Francisco
Price was ￥325,453, price is now ￥257,889 per person
￥257,889
per person
May 1 - May 4
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9.2/10 Wonderful! (1,000 reviews)
Hotel Nia, Autograph Collection

Hotel Nia, Autograph Collection

4.5 out of 5
Price was ￥277,735, price is now ￥221,364 per person
￥221,364
per person
May 18 - May 20
found 12 hours ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
9/10 Wonderful! (522 reviews)
The rooms are great. The hotel is beautifully designed.

Reviewed on Feb 19, 2026

Inn At The Opera

Inn At The Opera

3.5 out of 5
Fillmore District
Price was ￥229,236, price is now ￥183,002 per person
￥183,002
per person
Apr 28 - May 3
found 1 day ago
Roundtrip flight included
Tokyo (TYO) to San Francisco (SFO)
8.4/10 Very Good! (700 reviews)
The staff was super friendly and helpful. I also loved the overall vibe! Very charming!

Reviewed on Feb 4, 2026

Where to stay in Downtown South San Francisco

Find the best Downtown South San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown South San Francisco
Vibrant activity in Union Square, San Francisco with palm trees and bustling city life

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown South San Francisco Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundable
The price is ￥18,612 per night from Mar 1 to Mar 2
￥18,612
￥21,905 total
Mar 1 - Mar 2
includes taxes & fees
9/10 Wonderful! (5,337 reviews)
Room was so clean and staff were very polite and friendly.

Reviewed on Feb 26, 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥20,603 per night from Mar 3 to Mar 4
￥20,603
￥30,681 total
Mar 3 - Mar 4
includes taxes & fees
9/10 Wonderful! (7,312 reviews)
Hot water

Reviewed on Feb 26, 2026

Hotel Riu Plaza Fisherman's Wharf
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ￥24,439 per night from Mar 28 to Mar 29
￥24,439
￥28,763 total
Mar 28 - Mar 29
includes taxes & fees
8.8/10 Excellent! (2,897 reviews)
Awesome historical hotel centrally located just steps away from Union Square and Powell St. The hotel staff was very friendly and helpful. Tne rooms comfortable and spacious. The only disadvantage is that the hotel doesn’t have a restaurant or coffee shop. There is a little smell throughout the property. ...

Reviewed on Feb 25, 2026

Handlery Union Square Hotel
See all 4,838 properties in Downtown South San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Downtown South San Francisco vacation package cost?
From just ￥146,956. Yes, you read that right. Our Downtown South San Francisco vacation packages are a simple way to make your dollar go further. Combine your favorite hotels, flights and car rentals and get to know this popular destination.
How do I get a cheap travel package to Downtown South San Francisco?
Bundle your bookings with Expedia to save on your next big adventure. With more than 550 airlines and 1,000,000 properties globally, your Downtown South San Francisco vacation package can be tailored exactly to suit your travel style. With all those extra dollars, why not add one or two interesting tours and activities? It's an easy way to unlock even more bargains. That dream vacation to Downtown South San Francisco is much closer than you thought!
Where should I stay in Downtown South San Francisco?
A trip to Downtown South San Francisco wouldn't be complete without seeing South San Francisco Convention Center, Sees Candies and K1 Speed San Francisco. Spend your nights close to these top attractions and make sightseeing easy.
What are the top hotels in Downtown South San Francisco?
Book a stay at Airport Inn. It's one of this area's most sought-after hotels. Another well-known option in Downtown South San Francisco is Rustic/modern Design, Oasis City Getaway.
How far in advance should I book my Downtown South San Francisco vacation?
Travelers are generally able to look up international airfares on Expedia up to a year in advance of departure. Booking at the last minute? With a stroke of luck, it's still possible to purchase a cheaper ticket only weeks before your journey.
What does an Expedia Downtown South San Francisco travel package include?
With Expedia, you can choose a combination of hotels, flights and car rentals to build your perfect Downtown South San Francisco travel package. Once you've made your booking, you can add on all the fun stuff like activities and tours. Don't forget, the more you bundle, the more cash you'll save!
What should I know before booking a Downtown South San Francisco travel package?
When you book your hotels, flights and car rentals together, you'll land great discounts. Whether you're organizing an outdoor getaway in a chalet or prefer to stay in a ritzy city hotel, Expedia can help make it happen.
Can I choose my airline with a Downtown South San Francisco Expedia vacation package?
Definitely. Expedia has more than 550 airline partners to select from all over the world. With all that choice, finding the ideal carrier to whisk you away to Downtown South San Francisco will be a cinch.
If I'm not able to travel, can I cancel my Downtown South San Francisco vacation package?
It's impossible to predict what tomorrow might bring, so it's comforting to know that you can change or cancel your Downtown South San Francisco vacation package. If you booked in the last 24 hours, you may be entitled to a refund. If it's an older booking, your hotel, airline or car rental company may charge a fee. Visit our Customer Service Portal for more information.

Discover the most popular places to visit in Downtown South San Francisco

Golden Gate Bridge illuminated at night with city lights in the background in California, USA

Golden Gate Bridge

Cars trundle across it and ships sail under it, but the best way to experience this iconic bridge is on foot.

Golden Gate Bridge
Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Vibrant crowds enjoying Pier 39 with shops, dining, and views of the San Francisco Bay

Pier 39

This waterfront attraction offers thrilling rides, innovative street performers and colorful souvenir shops, but it’s the sea lions that win the day.

Pier 39

Things to do

Alcatraz Island Prison Tour Package

Official Alcatraz Island Prison Tour with Free App Audio Packages

￥11,918
per adult
100% of travellers recommend
Official Alcatraz Island Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

￥7,584
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

￥8,977
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.