Find Resorts & Hotels with Spas in St. Charles, MO
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Check availability on St. Charles Resorts & Hotels with Spas
Top St. Charles Resorts & Hotels with Spas
Our top choices for St. Charles hotels with a spa

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1006)
The price is ¥27,444
¥34,521 total
includes taxes & fees
Sep 8 - Sep 9

21C Museum Hotel St Louis
21C Museum Hotel St Louis
9.0 out of 10, Wonderful, (1348)
The price is ¥23,751
¥28,509 total
includes taxes & fees
Oct 5 - Oct 6

Four Seasons Hotel St Louis
Four Seasons Hotel St Louis
9.4 out of 10, Exceptional, (1001)
The price is ¥62,658
¥73,264 total
includes taxes & fees
Sep 21 - Sep 22

The Ritz-Carlton, St. Louis
The Ritz-Carlton, St. Louis
9.2 out of 10, Wonderful, (547)
The price is ¥72,093
¥83,982 total
includes taxes & fees
Oct 5 - Oct 6
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Spa hotels with pools in St. Charles

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1006)
The price is ¥27,444
¥34,521 total
includes taxes & fees
Sep 8 - Sep 9
Spa hotels with hot tubs in St. Charles

Ameristar Casino Resort and Spa
Ameristar Casino Resort and Spa
8.4 out of 10, Very Good, (1006)
The price is ¥27,444
¥34,521 total
includes taxes & fees
Sep 8 - Sep 9
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top St. Charles Hotel Reviews

Ameristar Casino Resort and Spa
10/10 Excellent
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Find More Hotels near St. Charles
More Hotel Options in St. Charles
More Accommodation Types in St. Charles
Hotels near popular St. Louis Attractions
Explore more hotels
- Sonesta ES Suites St. Louis - Chesterfield
- The Arch Convention Hotel
- 21C Museum Hotel St Louis
- River City Casino & Hotel
- Pear Tree Inn St. Louis Airport
- Marriott St. Louis Grand
- Forest Park Hotel by MDR
- Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
- Drury Inn & Suites St. Louis Union Station
- AC Hotel St. Louis Clayton
- Live by Loews - St.Louis
- Moonrise Hotel
- Pear Tree Inn St. Louis Convention Center
- Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
- Hilton St. Louis at the Ballpark
- Drury Inn & Suites St. Louis Airport