A calm lake reflecting trees with autumn foliage, a clear sky, and a distant shoreline.

St. Charles Vacation Rentals

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Check prices for these dates

In two weeks
Jul 24 - Jul 26
In two months
Sep 4 - Sep 6
In three months
Oct 2 - Oct 4
In four months
Oct 30 - Nov 1

Our top choices for St. Charles vacation rentals

Fridge, microwave, oven, stovetop

The Chalet | St Charles 2BR Private Retreat on 1.2 Acres | By Mercer Stays

The Chalet | St Charles 2BR Private Retreat on 1.2 Acres | By Mercer Stays
Saint Charles
8.8 out of 10, Excellent, (3 reviews)
"We loved the location for our travel needs and we had everything we needed for a family of two adults and two dogs. "
United States
Leslie R.
The price is ￥43,835
￥94,083 total
includes taxes & fees
Jul 12 - Jul 13
The Chalet | St Charles 2BR Private Retreat on 1.2 Acres | By Mercer Stays
Exterior

HotTub-2br2b-near Historic Main Street

HotTub-2br2b-near Historic Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (8 reviews)
"Easy check in, very clean, great location. Amazing hot tub! Perfect for a girl's weekend!"
United States
Kara A.
The price is ￥27,441
￥53,129 total
includes taxes & fees
Jul 20 - Jul 21
HotTub-2br2b-near Historic Main Street
Interior

The Reunion House | St Charles 4BR Sleeps 14 Game Room Hot Tub | Mercer Stays

The Reunion House | St Charles 4BR Sleeps 14 Game Room Hot Tub | Mercer Stays
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Such a perfect place to stay for a weekend with a larger group! Close to a lot of different things and had pretty much everything you could need. It was also super clean and nice! "
United States
Amanda P.
The price is ￥66,351
￥153,573 total
includes taxes & fees
Jul 9 - Jul 10
The Reunion House | St Charles 4BR Sleeps 14 Game Room Hot Tub | Mercer Stays
Fridge, microwave, oven, stovetop

The Stadium by Mercer Stays | Private 2.2Acre Sports Estate for Teams & Families

The Stadium by Mercer Stays | Private 2.2Acre Sports Estate for Teams & Families
Saint Charles
The price is ￥87,155
￥184,510 total
includes taxes & fees
Jul 12 - Jul 13
The Stadium by Mercer Stays | Private 2.2Acre Sports Estate for Teams & Families
TV

Main Street Apartment

Main Street Apartment
St. Charles Historic District
9.6 out of 10, Exceptional, (39 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
The price is ￥26,252
￥72,916 total
includes taxes & fees
Jul 26 - Jul 27
Main Street Apartment
Fridge, microwave, oven, stovetop

The Getaway House | St Charles 4BR Sleeps 11 Game Room | Hot Tub | Mercer Stays

The Getaway House | St Charles 4BR Sleeps 11 Game Room | Hot Tub | Mercer Stays
Saint Charles
10.0 out of 10, Exceptional, (6 reviews)
"The home was very clean and had what we needed for our stay. The host was easy to communicate with and we had no issues. We would definitely stay again! "
United States
Mary L.
The price is ￥37,263
￥124,717 total
includes taxes & fees
Aug 5 - Aug 6
The Getaway House | St Charles 4BR Sleeps 11 Game Room | Hot Tub | Mercer Stays
Smart TV, stereo

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!

Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
St. Charles Historic District
9.6 out of 10, Exceptional, (79 reviews)
"Great location and beautiful place. Had a wonderful time. "
United States
Ernest R.
The price is ￥21,067
￥42,634 total
includes taxes & fees
Jul 26 - Jul 27
Aunt Doodle’s House 8 blocks from Historic Main Street.. Convenient location!
TV

Walk to St. Charles Entertainment

Walk to St. Charles Entertainment
Saint Charles
9.0 out of 10, Wonderful, (10 reviews)
"We really enjoyed our stay. The house was clean, spacious, and very accommodating. We stayed for a dance competition and the proximity to the convention center was unbeatable. "
United States
Chloe
The price is ￥20,127
￥52,563 total
includes taxes & fees
Jul 16 - Jul 17
Walk to St. Charles Entertainment
Fridge, microwave, oven, stovetop

Historic 1908 Frenchtown Home

Historic 1908 Frenchtown Home
St. Charles Historic District
8.6 out of 10, Excellent, (23 reviews)
"yes the kitchen was fully equipped."
Canada
David M.
The price is ￥26,252
￥58,555 total
includes taxes & fees
Aug 2 - Aug 3
Historic 1908 Frenchtown Home
Property grounds

The Driftwood Den | Boho-Inspired 2-Bedroom

The Driftwood Den | Boho-Inspired 2-Bedroom
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Loved our stay here. Clean, comfortable, convenient. Couldn’t have been easier, in all aspects. Already plan to stay there again!!!"
United States
Kourtney S.
The price is ￥20,127
￥51,173 total
includes taxes & fees
Jul 12 - Jul 13
The Driftwood Den | Boho-Inspired 2-Bedroom
Interior

Spacious 2 Bedroom Townhome

Spacious 2 Bedroom Townhome
Saint Charles
8.0 out of 10, Very Good, (16 reviews)
"Quiet area and clean rooms"
United States
Chelsie H.
The price is ￥19,252
￥51,557 total
includes taxes & fees
Jul 13 - Jul 14
Spacious 2 Bedroom Townhome
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (112 reviews)
"Really liked the location, lots to do within walking distance. Very good check in process - easy to follow.Well maintained place."
United States
William H.
The price is ￥22,525
￥45,246 total
includes taxes & fees
Jul 16 - Jul 17
Prime Loft of Main Street
Smart TV, fireplace, computer monitors

Charming open 4bd and screen-in porch! Sleeps 10!

Charming open 4bd and screen-in porch! Sleeps 10!
Saint Charles
9.2 out of 10, Wonderful, (46 reviews)
"Everything about the property was great. Very roomy and felt like home. "
United States
Dan R.
The price is ￥61,904
￥128,125 total
includes taxes & fees
Jul 11 - Jul 12
Charming open 4bd and screen-in porch! Sleeps 10!
TV

Music House · Music House on Main Street at The Wine Garden

Music House · Music House on Main Street at The Wine Garden
Saint Charles
9.4 out of 10, Exceptional, (17 reviews)
"Nice area nice place and communication"
United States
Zack P.
The price is ￥81,025
￥145,521 total
includes taxes & fees
Jul 9 - Jul 10
Music House · Music House on Main Street at The Wine Garden
Interior

2 Bdr Upstairs Apt Walking Distance to Main St

2 Bdr Upstairs Apt Walking Distance to Main St
Saint Charles
8.0 out of 10, Very Good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is ￥17,851
￥47,159 total
includes taxes & fees
Jul 12 - Jul 13
2 Bdr Upstairs Apt Walking Distance to Main St
Combined shower/tub, hair dryer, towels, soap

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!

New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
St. Charles Historic District
9.6 out of 10, Exceptional, (76 reviews)
"The property was large and bright with a perfect fenced in backyard and met all of our needs."
United States
LeAnne R.
New Remodel in St. Charles - Sleeps 10! New patio! Large Fenced-in backyard!
TV, books

St. Charles 1860's Gem - Sleeps 6!

St. Charles 1860's Gem - Sleeps 6!
St. Charles Historic District
9.8 out of 10, Exceptional, (158 reviews)
"Very nice historical place "
United States
Shawntell C.
The price is ￥23,497
￥47,882 total
includes taxes & fees
Jul 22 - Jul 23
St. Charles 1860's Gem - Sleeps 6!
TV

Walk to Main St | Pet-Friendly Apt

Walk to Main St | Pet-Friendly Apt
St. Charles Historic District
8.6 out of 10, Excellent, (16 reviews)
"Property was as advertised. Perfect for my needs, clean, quiet and convenient. Loved Historic St. Charles. Would recommend anytime! Thank you! "
United States
Brian B.
The price is ￥21,877
￥52,286 total
includes taxes & fees
Jul 22 - Jul 23
Walk to Main St | Pet-Friendly Apt
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (65 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is ￥22,525
￥44,922 total
includes taxes & fees
Jul 12 - Jul 13
Amazing Renovated Historic Loft on Main Street
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (2 reviews)
"Excellent"
United States
Scott N.
The price is ￥16,043
￥46,081 total
includes taxes & fees
Jul 12 - Jul 13
6th street 101 - Walk to Main St
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

8/10 Good
"Weird stuff. Loud icemaker made one room unacceptable. The next rooms drawers came open with clothes in them. Pool and deck area awesome-but gets crowded. Decent laundry. Good breakfast, very friendly staff."
Paul 4-night trip
Posted 1 hour ago
Drury Plaza Hotel St. Louis at the Arch

Find out more about St. Charles

Search for holiday rentals in St. Charles on Expedia! You can easily find your home rentals, villas, holiday apartments in St. Charles using one of the methods below:

  • View our selection of featured holiday rentals in St. Charles
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Look no further and take a look at our great range of rental properties in St. Charles!

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, you can find vacation rentals near popular attractions in St. Charles, or you can choose a secluded option if you're looking for relaxation. Tourists like the array of shops and top-notch restaurants in St. Charles. The live music and theater scene are some other things you might like to check out during your trip.

What are some of the best vacation rentals that St. Charles has to offer?

The St. Charles Guest House, lovely historic home, fun for families and groups: This St. Charles vacation home rental is located on a river and has a fireplace, a selection of games, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Some other top choices in St. Charles are 🌟 Adorable Historic 🏠 in the ❤️ of St. Charles 🌟 and St. Charles 1860's Gem - Sleeps 6!.

How many vacation rentals are there in St. Charles?

Expedia has 85 vacation rentals for your stay in St. Charles.

What can I see and do in St. Charles?

Katy Trail and Mississippi River are a couple of scenic spots to enjoy the outdoors, whereas Missouri Artists on Main is one of the cultural attractions. Other places in town to visit include Historic Main Street and Lewis & Clark Boathouse and Nature Center.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned accommodations you can book for several days or more in St. Charles. Vacation rentals provide amenities such as laundry facilities and kitchens to help you enjoy your stay. If you're concerned about a clean environment, vacation rentals can offer a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you the enjoyment of travel. You'll also have more space in a vacation rental than in a hotel, which makes a vacation rental an attractive option for a family getaway.