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Find hotels in San Francisco, Panama City from ¥7,282

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Discover 1,545 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Aloft Panama

3.5 star property
8.6 out of 10, Excellent, (855)
"The buffet breakfast was excellent and staff was very friendly. "
The price is ¥17,521
¥19,273 total
includes taxes & fees
Oct 3 - Oct 4
Aloft Panama

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
8.8 out of 10, Excellent, (1001)
"The breakfast buffet was excellent and the staff was friendly "
The price is ¥18,734
¥20,607 total
includes taxes & fees
Oct 25 - Oct 26
Courtyard by Marriott Panama Multiplaza Mall

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
9.6 out of 10, Exceptional, (1057)
"Family-friendly hotel, tasty breakfast options daily and overall friendly staff and clean space."
The price is ¥15,911
¥17,503 total
includes taxes & fees
Sep 28 - Sep 29
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (953)
"Great staff and beautiful hotel. Will definitely stay again!"
The price is ¥20,081
¥22,090 total
includes taxes & fees
Oct 4 - Oct 5
Sheraton Grand Panama

Boutique Apartments Panamá Coco del Mar

3.5 star property
7.6 out of 10, Good, (131)
"Great view with access to the pool and gym."
The price is ¥4,397
¥25,098 total
includes taxes & fees
Sep 28 - Sep 29
Boutique Apartments Panamá Coco del Mar

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (1095)
"Great place "
The price is ¥19,024
¥20,926 total
includes taxes & fees
Sep 27 - Sep 28
Megapolis Hotel Panamá

Plaza Paitilla Inn Hotel

3.5 star property
9.4 out of 10, Exceptional, (2127)
"Stayed 4 nights excellent property and views from the room"
The price is ¥22,613
¥24,874 total
includes taxes & fees
Sep 28 - Sep 29
Plaza Paitilla Inn Hotel

JW Marriott Panama

5.0 star property
8.8 out of 10, Excellent, (1014)
"The staff is top notch, the accommodations amazing, the dining options great, close to airport and activities "
The price is ¥34,240
¥37,664 total
includes taxes & fees
Oct 10 - Oct 11
JW Marriott Panama

Decapolis Hotel Panama City

4.0 star property
8.6 out of 10, Excellent, (1342)
"Good price , location and tasty breakfast "
The price is ¥12,665
¥13,931 total
includes taxes & fees
Sep 28 - Sep 29
Decapolis Hotel Panama City

Las Americas Golden Tower Panama

4.0 star property
9.0 out of 10, Wonderful, (1026)
"Very friendly staff, room was also very clean"
The price is ¥21,628
¥23,790 total
includes taxes & fees
Sep 27 - Sep 28
Las Americas Golden Tower Panama

San Francisco by Wynwood House

3.0 star property
9.2 out of 10, Wonderful, (50)
"Good comfy rooms"
The price is ¥14,017
¥19,537 total
includes taxes & fees
Sep 28 - Sep 29
San Francisco by Wynwood House

Residence Inn by Marriott Panama City

4.0 star property
9.0 out of 10, Wonderful, (516)
"Stayed here while a relative was hospitalized, easy access to the hospital and shopping center with lots of food options. If visiting Panama city it is very conveniently located."
The price is ¥20,239
¥22,263 total
includes taxes & fees
Oct 25 - Oct 26
Residence Inn by Marriott Panama City

Boutique Apartments Atlapa

3.0 star property
7.2 out of 10, Good, (20)
"The area was great, just a short walk to many great places to eat and the supermarket. We enjoyed the facilities and the staff was always friendly and easy to deal with/talk to. Fantastic place to stay."
Boutique Apartments Atlapa

Casa Orquídea

2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
The price is ¥9,629
¥10,592 total
includes taxes & fees
Sep 27 - Sep 28
Casa Orquídea

Wanders Panama by Boutique Apartments

4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
The price is ¥9,628
¥26,899 total
includes taxes & fees
Sep 28 - Sep 29
Wanders Panama by Boutique Apartments

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
The price is ¥14,703
¥20,620 total
includes taxes & fees
Sep 28 - Sep 29
w Bright 1BR w Private Balcony in San Francisco

w Premium 1BR w Balcony in San Francisco

2.0 star property
The price is ¥15,958
¥22,001 total
includes taxes & fees
Oct 5 - Oct 6
w Premium 1BR w Balcony in San Francisco

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2251)
"Great hotel near the airport "
The price is ¥18,270
¥20,097 total
includes taxes & fees
Oct 25 - Oct 26
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
9.0 out of 10, Wonderful, (1003)
"The hotel is so beautiful, the people are very friendly and helpful!"
Central Hotel Panama Casco Viejo

Hotel Riu Plaza Panama

5.0 star property
9.0 out of 10, Wonderful, (4339)
"Excellent stay!!"
The price is ¥17,770
¥19,547 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

Calidonia

You might enjoy the shopping while in Calidonia. Cinta Costera is a notable sight, and you can get around town at Estación Lotería or Santo Tomas Station to see more of the city.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is San Francisco like?

San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.

Where is the best hotel for a stay in San Francisco?

Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.

How many hotels will I find in San Francisco?

If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 216 San Francisco hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in San Francisco, will I receive a refund?

Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.

Where can I learn more about changing or cancelling my trip to San Francisco?

For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.

What is there to do in this Panama City neighborhood?

While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.