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Find hotels in San Francisco, Panama City from ¥12,846

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Discover 1,380 San Francisco hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Courtyard by Marriott Panama Multiplaza Mall

4.0 star property
San Francisco
8.8 out of 10, Excellent, (1002)
"Nice option in a nice area"
United States
Esteban
The price is ¥18,779
¥20,656 total
includes taxes & fees
Dec 6 - Dec 7
Courtyard by Marriott Panama Multiplaza Mall

Aloft Panama

3.5 star property
San Francisco
8.6 out of 10, Excellent, (878)
"Amazing hotel to stay when you visit Panama city"
United States
Melisa
The price is ¥16,953
¥18,648 total
includes taxes & fees
Nov 23 - Nov 24
Aloft Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1083)
"Good location, Spotless room, friendly and helpful staff"
United States
JOSE JULIAN
The price is ¥18,648
¥20,513 total
includes taxes & fees
Dec 12 - Dec 13
Ramada Plaza by Wyndham Panama Punta Pacifica

Sheraton Grand Panama

4.0 star property
San Francisco
8.6 out of 10, Excellent, (975)
"Centrally located and friendly staff "
United States
Julio
The price is ¥20,712
¥22,784 total
includes taxes & fees
Nov 21 - Nov 22
Sheraton Grand Panama

Plaza Paitilla Inn Hotel

3.5 star property
San Francisco
9.4 out of 10, Exceptional, (2126)
"Very nice hotel, all amenities met our needs. "
Canada
gordon
The price is ¥24,258
¥26,684 total
includes taxes & fees
Nov 12 - Nov 13
Plaza Paitilla Inn Hotel

Boutique Apartments Panamá Coco del Mar

3.5 star property
San Francisco
7.4 out of 10, Good, (148)
"GORGEOUS view!!! And very spacious "
United States
christine
The price is ¥5,260
¥27,296 total
includes taxes & fees
Nov 16 - Nov 17
Boutique Apartments Panamá Coco del Mar

Megapolis Hotel Panamá

4.5 star property
San Francisco
8.4 out of 10, Very Good, (1186)
"The hotel is great and the staff was helpful and accommodating."
United States
jimmie
The price is ¥18,847
¥20,732 total
includes taxes & fees
Dec 7 - Dec 8
Megapolis Hotel Panamá

JW Marriott Panama

5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
"The rooms were amazing "
United States
Andrae Kevin
The price is ¥30,383
¥33,422 total
includes taxes & fees
Dec 7 - Dec 8
JW Marriott Panama

Las Americas Golden Tower Panama

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (1004)
"Wonderful stay!"
United States
Martha
The price is ¥21,244
¥23,369 total
includes taxes & fees
Nov 14 - Nov 15
Las Americas Golden Tower Panama

Boutique Apartments Atlapa

3.0 star property
San Francisco
7.6 out of 10, Good, (23)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa

Decapolis Hotel Panama City

4.0 star property
San Francisco
8.6 out of 10, Excellent, (1392)
"Very nice Hotel "
United States
Marcos
The price is ¥11,678
¥12,846 total
includes taxes & fees
Nov 23 - Nov 24
Decapolis Hotel Panama City

Residence Inn by Marriott Panama City

4.0 star property
San Francisco
9.0 out of 10, Wonderful, (527)
"It is located in a mall so most everything you might need is right there. Friendly staff and very clean and spacious rooms. I will stay here again."
United States
Steve
The price is ¥22,039
¥24,242 total
includes taxes & fees
Dec 8 - Dec 9
Residence Inn by Marriott Panama City

San Francisco by Wynwood House

3.0 star property
San Francisco
9.2 out of 10, Wonderful, (52)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
The price is ¥15,529
¥21,302 total
includes taxes & fees
Nov 16 - Nov 17
San Francisco by Wynwood House

Wanders Panama by Boutique Apartments

4.0 star property
San Francisco
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is ¥17,398
¥42,596 total
includes taxes & fees
Nov 16 - Nov 17
Wanders Panama by Boutique Apartments

Casa Orquídea

2.0 star property
San Francisco
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
United States
Natalia
The price is ¥13,442
¥14,786 total
includes taxes & fees
Dec 10 - Dec 11
Casa Orquídea

Dovle Residences by HMS-Preferred Member

3.0 star property
San Francisco
The price is ¥26,926
¥29,688 total
includes taxes & fees
Dec 1 - Dec 2
Dovle Residences by HMS-Preferred Member

w Bright 1BR w Private Balcony in San Francisco

2.0 star property
San Francisco
The price is ¥14,512
¥20,519 total
includes taxes & fees
Nov 12 - Nov 13
w Bright 1BR w Private Balcony in San Francisco

w Premium 1BR w Balcony in San Francisco

2.0 star property
San Francisco
The price is ¥15,614
¥21,731 total
includes taxes & fees
Nov 22 - Nov 23
w Premium 1BR w Balcony in San Francisco

Crowne Plaza Panama Airport by IHG

4.0 star property
15.7 km from San Francisco
8.4 out of 10, Very Good, (2263)
"Great location near airport updated hotel "
Canada
Joe
The price is ¥18,717
¥20,589 total
includes taxes & fees
Nov 28 - Nov 29
Crowne Plaza Panama Airport by IHG

Central Hotel Panama Casco Viejo

4.0 star property
San Felipe, 5.4 km from San Francisco
9.0 out of 10, Wonderful, (1003)
"This Hotel is amazing! From the greetings at check in to the good bye at check out the staff were very attentive and amazing. The hotel has 4 restaurants each one with a different theme and food selection; we tried all and the food, prices, and staff were beyond of amazing. Hotel is in the center of Casco Viejo, very close to all attractions. Thank you the staff and I will definitely will recommend."
United States
Joel
The price is ¥34,558
¥38,014 total
includes taxes & fees
Nov 17 - Nov 18
Central Hotel Panama Casco Viejo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

If you're spending some time in San Felipe, Interoceanic Canal Museum and National Theater are top sights worth seeing.

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

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Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighborhood that travelers like for its restaurants. Be sure to check out Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighborhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels will I find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 184 San Francisco hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get top deals in San Francisco.
Where can I learn more about changing or cancelling my trip to San Francisco?
For additional details about updating your trip to San Francisco or cancelling it, head over to our customer service page.
What is there to do in this Panama City neighborhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa, or Pacific Center, might be the perfect place to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops to visit in the neighborhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90, and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.