Find hotels in Panhandle, San Francisco

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Panhandle hotels

The Metro Hotel

The Metro Hotel
2.5 star property
Panhandle
9.2 out of 10, Wonderful, (286)
"Great location, fun neighborhood!"
United States
Madelyn
The Metro Hotel

The Millwood - A Boutique Hotel

The Millwood - A Boutique Hotel
3.0 star property
18.5 km from Panhandle
9.2 out of 10, Wonderful, (1005)
"Great hotel, convenient, clean, comfortable, quiet, great free breakfast and perfect price. Would definitely stay again!"
United States
Allison
The price is ¥20,481
¥25,224 total
includes taxes & fees
Jan 1 - Jan 2, 2026
The Millwood - A Boutique Hotel

Royal Pacific Motor Inn

Royal Pacific Motor Inn
2.0 star property
Russian Hill, 4.4 km from Panhandle
9.0 out of 10, Wonderful, (1005)
"Clean room, great staff, convenient location "
United States
Chia Wee
The price is ¥14,560
¥17,137 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Royal Pacific Motor Inn

Hotel Nova SFO

Hotel Nova SFO
2.5 star property
14.9 km from Panhandle
8.6 out of 10, Excellent, (1005)
"Great hospitality staff is awesome will definitely stay here again !!"
United States
Cindy
The price is ¥14,091
¥16,562 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Hotel Nova SFO

The Westin San Francisco Airport

The Westin San Francisco Airport
4.0 star property
19.7 km from Panhandle
8.8 out of 10, Excellent, (2019)
"Comfortable room, welcome glass of wine, easy shuttle to and from airport, friendly staff."
United States
Carole
The price is ¥16,052
¥23,017 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Westin San Francisco Airport

La Quinta Inn & Suites by Wyndham San Francisco Airport West

La Quinta Inn & Suites by Wyndham San Francisco Airport West
3.0 star property
18.5 km from Panhandle
8.6 out of 10, Excellent, (1514)
"Clean room, decent breakfast. Close to airport. "
United States
Karen
The price is ¥19,963
¥22,947 total
includes taxes & fees
Jan 24 - Jan 25, 2026
La Quinta Inn & Suites by Wyndham San Francisco Airport West

Aloft San Francisco Airport

Aloft San Francisco Airport
3.0 star property
19.8 km from Panhandle
9.0 out of 10, Wonderful, (2250)
"Spotless — not fancy but clean open and comfortable !!! Great airport hotel!!!!"
United States
Michael
The price is ¥17,636
¥20,271 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Aloft San Francisco Airport

Home2 Suites by Hilton San Francisco Airport North

Home2 Suites by Hilton San Francisco Airport North
3.0 star property
13.4 km from Panhandle
8.8 out of 10, Excellent, (1168)
"Amazing stay very clean and friendly staff "
United States
Norma
The price is ¥17,141
¥20,094 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Home2 Suites by Hilton San Francisco Airport North

Hotel Ikon

Hotel Ikon
2.5 star property
Union Square, 4 km from Panhandle
7.0 out of 10, Good, (450)
"There are many restaurants nearby, BART was less than a 10min walk. Very convenient"
United States
Laresa
The price is ¥15,753
¥18,510 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Ikon

SFO El Rancho Inn SureStay Collection by Best Western

SFO El Rancho Inn SureStay Collection by Best Western
3.0 star property
18.8 km from Panhandle
8.4 out of 10, Very Good, (2977)
"The food was great in the morning very pleasant atmosphere the room was clean I will use them again when I go to San Francisco"
United States
matt
The price is ¥13,042
¥15,090 total
includes taxes & fees
Jan 2 - Jan 3, 2026
SFO El Rancho Inn SureStay Collection by Best Western

Marin Suites Hotel

Marin Suites Hotel
3.0 star property
18.9 km from Panhandle
8.4 out of 10, Very Good, (1003)
"Clean room, amazing service, quiet, lovely setting - couldn't be more happy!"
United States
Jennifer
The price is ¥20,250
¥22,719 total
includes taxes & fees
Dec 31 - Jan 1, 2026
Marin Suites Hotel

Inn at Rockaway San Francisco Pacifica

Inn at Rockaway San Francisco Pacifica
2.5 star property
18.7 km from Panhandle
8.2 out of 10, Very Good, (1005)
"Second time staying here and it was perfect for a quick weekend get away. The location is excellent and the staff is so kind and helpful. "
United States
Kristin
Inn at Rockaway San Francisco Pacifica

Embassy Suites by Hilton San Francisco Airport Waterfront

Embassy Suites by Hilton San Francisco Airport Waterfront
3.5 star property
21.9 km from Panhandle
8.6 out of 10, Excellent, (1869)
"Great room, friendly, great breakfast"
United States
Lisa
The price is ¥20,335
¥23,120 total
includes taxes & fees
Jan 23 - Jan 24, 2026
Embassy Suites by Hilton San Francisco Airport Waterfront

The Dylan at SFO

The Dylan at SFO
3.0 star property
20.1 km from Panhandle
9.2 out of 10, Wonderful, (1841)
"Clean Room, Nice Staff, Safe, Close to airport"
United States
Tiffeny
The price is ¥17,033
¥20,287 total
includes taxes & fees
Jan 4 - Jan 5, 2026
The Dylan at SFO

The Evergreen

The Evergreen
2.0 star property
18 km from Panhandle
9.2 out of 10, Wonderful, (387)
"Rooms are nice and modern"
Canada
Daniel
The price is ¥16,205
¥18,150 total
includes taxes & fees
Dec 31 - Jan 1, 2026
The Evergreen

White Swan Inn

White Swan Inn
3.5 star property
Union Square, 3.7 km from Panhandle
9.4 out of 10, Exceptional, (1005)
"Great place to stay in San Fransisco "
Canada
Daniel
The price is ¥17,168
¥24,261 total
includes taxes & fees
Jan 1 - Jan 2, 2026
White Swan Inn

The Marina Inn on San Francisco Bay

The Marina Inn on San Francisco Bay
3.5 star property
24.2 km from Panhandle
8.6 out of 10, Excellent, (2305)
"Clean, cozy, great staff!"
United States
Stacie
The price is ¥16,396
¥18,691 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Marina Inn on San Francisco Bay

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

Holiday Inn Express Hotel & Suites Oakland-Airport by IHG
2.5 star property
22.4 km from Panhandle
8.8 out of 10, Excellent, (1008)
"Very nice rooms, friendly staff, good breakfast"
United States
Dana
The price is ¥17,223
¥21,832 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Hotel & Suites Oakland-Airport by IHG

San Remo Hotel

San Remo Hotel
2.0 star property
North Beach, 4.6 km from Panhandle
8.8 out of 10, Excellent, (1001)
"The staff was absolutely friendly, helpful, and welcoming. The property has so much charm and character. Would definitely stay here again!"
United States
Anna
San Remo Hotel

Mayflower Hotel

Mayflower Hotel
2.0 star property
3.5 km from Panhandle
8.8 out of 10, Excellent, (220)
"Everything was as expected, people in the motel very friendly and breakfast was excellent "
United States
Sergio
The price is ¥14,848
¥17,446 total
includes taxes & fees
Jan 29 - Jan 30, 2026
Mayflower Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Panhandle

Find the best Panhandle areas and neighborhoods for the activities you enjoy most.

Union Square

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Fisherman's Wharf

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

South of Market

From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.

Nob Hill

Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.

Top Panhandle Hotel Reviews

Frequently asked questions

What is Panhandle like?
Travelers will be sure to enjoy their time in San Francisco's Panhandle neighborhood.
What's a favorite place to stay in Panhandle?
Based on Expedia customer reviews, The Metro Hotel is the highest ranked property in Panhandle. This hotel offers free WiFi and Smart TVs.
How many hotels are there in Panhandle?
Book one of Expedia's 8 hotels and other accommodations in Panhandle and start exploring everything San Francisco has to offer.
If I need to cancel my hotel reservation in Panhandle, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals available in Panhandle.
Where can I learn more about changing or cancelling my trip to Panhandle?
To access more information about rescheduling or cancelling your trip to Panhandle, head over to our customer service page.
What can I see and do in this San Francisco neighborhood?
A few places to visit in the area around Panhandle include Grateful Dead House, War Memorial Gymnasium, and First AME Zion Church. While you're out sightseeing, Tactile Dome and Patricia Sweetow Gallery are a couple of additional sights to visit in San Francisco.

Explore a world of travel with Expedia