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Our top choices for South Central Houston hotels

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.0 out of 10, Wonderful, (1,884 reviews)
"Extremely helpful staff, excellent service. Location is convenient to everything."
United States
Lori
Hotel Zaza Houston Museum District

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (499 reviews)
"We had dinner food was ok. "
United States
Lisa
The price is ¥13,322
¥15,587 total
includes taxes & fees
Feb 1 - Feb 2
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
2.0 star property
South Central Houston
9.8 out of 10, Exceptional, (60 reviews)
"Great location will stay again "
United States
Jason
The price is ¥18,785
¥21,981 total
includes taxes & fees
Jan 25 - Jan 26
Wanderstay Boutique Hotel

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,056 reviews)
"Great place to stay "
United States
Ernest
The price is ¥22,862
¥28,457 total
includes taxes & fees
Jan 18 - Jan 19
The Westin Houston Medical Center/Museum District

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (547 reviews)
"Good rooms and location, great staff!"
United States
Eugene
The price is ¥24,907
¥29,142 total
includes taxes & fees
Feb 5 - Feb 6
La Maison in Midtown an urban B&B

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,817 reviews)
"Good price, clean room, friendly and helpful staff."
United States
Kristoffer
The price is ¥12,814
¥15,178 total
includes taxes & fees
Feb 1 - Feb 2
Hilton Houston Plaza/Medical Center

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (202 reviews)
"I absolutely loved my stay here!!"
United States
Daniella
The price is ¥32,731
¥40,667 total
includes taxes & fees
Jan 26 - Jan 27
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,003 reviews)
"Love the intercontinental"
United States
Patrick
The price is ¥24,730
¥32,095 total
includes taxes & fees
Jan 18 - Jan 19
InterContinental Houston by IHG

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,000 reviews)
"Great experience"
United States
Gordon
The price is ¥25,402
¥34,805 total
includes taxes & fees
Jan 31 - Feb 1
Houston Marriott Medical Center/Museum District

Modern Cozy Home with King Bed

Modern Cozy Home with King Bed
3.5 star property
South Central Houston
9.2 out of 10, Wonderful, (24 reviews)
"Very spacious and close to just about everything. The view is amazing too"
United States
Brenden
The price is ¥34,255
¥70,211 total
includes taxes & fees
Feb 1 - Feb 2
Modern Cozy Home with King Bed

The Oasis Checkmate HTX Rooftop

The Oasis Checkmate HTX Rooftop
3.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"This place is amazing! Beautiful decor and location is perfect for any event near the convention center. Safe and secure. Hosts were responsive and friendly. I let them know the ironing board was missing and they had a new one sent from Amazon the next day! 10/10 recommend and will rebook. "
United States
Veronica
The price is ¥41,284
¥105,244 total
includes taxes & fees
Jan 29 - Jan 30
The Oasis Checkmate HTX Rooftop

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very Good, (190 reviews)
"This is an amazing place to stay."
United States
Darius
The price is ¥8,722
¥10,204 total
includes taxes & fees
Jan 23 - Jan 24
Wanderstay Houston Hostel

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,000 reviews)
"Nice hotel"
United States
Robert Jeanmard
The price is ¥11,189
¥13,090 total
includes taxes & fees
Jan 18 - Jan 19
Americas Best Value Inn Medical Center Downtown

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (229 reviews)
"A classical Motel like in a Movie. The staff was really kind and helpful."
United Kingdom
Lisa-Maria
The price is ¥10,673
¥12,488 total
includes taxes & fees
Jan 19 - Jan 20
Southmore Boulevard Motel

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
7.8 out of 10, Good, (48 reviews)
"Check in staff was friendly and room was clean."
United States
Alfredo
The price is ¥12,769
¥14,940 total
includes taxes & fees
Jan 24 - Jan 25
Downtowner Inns - Houston Downtown

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (890 reviews)
"Nice place to stay"
United States
Alexandra
The price is ¥24,505
¥28,670 total
includes taxes & fees
Jan 23 - Jan 24
Hilton University of Houston

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,005 reviews)
"Clean"
United States
William
The price is ¥9,248
¥10,864 total
includes taxes & fees
Jan 25 - Jan 26
Extended Stay America Suites Houston Med Ctr Braeswood Bl

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
3.0 star property
South Central Houston
The price is ¥33,906
¥104,399 total
includes taxes & fees
Jan 24 - Jan 25
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

Newly Built Modern 3 Bedroom Houston Home

Newly Built Modern 3 Bedroom Houston Home
2.0 star property
South Central Houston
10.0 out of 10, Exceptional, (2 reviews)
"The pictures do not do this property justice. The three story home has 3 beautiful bedrooms, each with luxurious bathrooms. The main bedroom and the living room has a small patio and then there's a rooftop seating area that is an excellent spot for gazing at the Houston night skyline. The quiet area is gated off a not too busy street in a beautiful neighborhood. We did have a couple of issues upon our arrival but the hosts were on top of it and had it resolved the next day. They have great...
United States
robin
The price is ¥22,451
¥64,345 total
includes taxes & fees
Jan 18 - Jan 19
Newly Built Modern 3 Bedroom Houston Home

Downtown Houston 3BR Bachelorette Escape

Downtown Houston 3BR Bachelorette Escape
2.0 star property
South Central Houston
9.6 out of 10, Exceptional, (5 reviews)
"Everything was great. Look no further and book this property. "
United States
Iesheal
Downtown Houston 3BR Bachelorette Escape
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Main Street Square Station.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

Top South Central Houston Hotel Reviews

Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out Continental Club and Midtown Arts and Theater Center Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other favorite options in the area include MyCrib Houston Hostel and InterContinental Houston by IHG.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1165 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and James Turrell's Twilight Epiphany Skyscape. Continental Club and Midtown Arts and Theater Center Houston are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station.

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