South Central Houston, TX

Houston

South Central Houston
South Central Houston
South Central Houston
South Central Houston
South Central Houston

Popular places to visit

Things to do


South Central Houston Hotel Deals

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
The price is ¥35,147 per night from Apr 2 to Apr 3
¥35,147
¥48,452 total
Apr 2 - Apr 3
includes taxes & fees
Book a stay at this luxury aparthotel in Houston. Enjoy free WiFi, a full-service spa, and a rooftop terrace. Our guests praise the helpful staff in our reviews. ...
9/10 Wonderful! (1,000 reviews)
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Reviewed on Mar 30, 2026

Hotel Zaza Houston Museum District
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
The price is ¥20,476 per night from Apr 5 to Apr 6
¥20,476
¥24,142 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,866 reviews)
I didn’t have breakfast but purchased drinks.

Reviewed on Mar 30, 2026

Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG

InterContinental Houston by IHG

4 out of 5
6750 Main St Houston TX
The price is ¥25,901 per night from Apr 5 to Apr 6
¥25,901
¥33,479 total
Apr 5 - Apr 6
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,001 reviews)
Everyone is always friendly as usual!

Reviewed on Mar 27, 2026

InterContinental Houston by IHG
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

4 out of 5
1709 DRYDEN ROAD Houston TX
The price is ¥30,000 per night from Apr 4 to Apr 5
¥30,000
¥37,341 total
Apr 4 - Apr 5
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,132 reviews)
Excellent breakfast options, great comfy room and walking distance to MD Anderson.

Reviewed on Mar 31, 2026

The Westin Houston Medical Center/Museum District
Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown

2 out of 5
2419 Riverside Dr Houston TX
The price is ¥13,175 per night from Apr 2 to Apr 3
¥13,175
¥15,415 total
Apr 2 - Apr 3
includes taxes & fees
Stay at this motel in Houston. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,007 reviews)
The sheets had stains all over them. The toilet leaked all over the floor. The outside of the building looks pretty updated, but the inside of the rooms were not good at all.

Reviewed on Apr 1, 2026

Americas Best Value Inn Medical Center Downtown
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4 out of 5
6800 Main Street Houston TX
The price is ¥16,638 per night from Apr 12 to Apr 13
¥16,638
¥19,466 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around South Central Houston

Greater Third Ward

Greater Third Ward

4/5(24 area reviews)

While you're in Greater Third Ward, take in top sights like Barbara Jordan & Mickey Leland Archives or Fertitta Center, and hop on the metro to see more the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.

Greater Third Ward
Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.

Midtown

4.5/5(46 area reviews)

Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line.

Midtown
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East Downtown Houston

4/5(11 area reviews)

Get to know East Downtown Houston and its many features like its restaurants and live music. You might want to explore sights like Shell Energy Stadium and Giant Beatles Statues, and you can jump on the metro at Leeland/Third Ward Station or EaDo/Stadium Station to get around the city.

East Downtown Houston
Museum District

Museum District

Known for its ample dining options and fascinating museums, there's plenty to explore in Museum District. You can visit top attractions like Children's Museum of Houston and Houston Natural Science Museum, and jump on the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.

Museum District
Houston Central Business District

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Houston Central Business District
Downtown Houston

Downtown Houston

4.5/5(2,329 area reviews)

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

Downtown Houston


South Central Houston, TX

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