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Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

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Compare top hotels in South Central Houston

A spacious living area with a dining table, chairs, and a chandelier.

Hotel Zaza Houston Museum District

4.5 star property
South Central Houston
View
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

Hilton Houston Plaza/Medical Center

4.5 star property
South Central Houston
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A spacious lobby with modern furniture, large windows, and indoor plants.

InterContinental Houston by IHG

4.0 star property
South Central Houston
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A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

Downtowner Inns - Houston Downtown

2.0 star property
South Central Houston
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A rooftop pool area with lounge chairs and a view of a tall building at night.

The Westin Houston Medical Center/Museum District

4.0 star property
South Central Houston
View
9.2
Wonderful
1,000 reviews
8.6
Excellent
2,204 reviews
9.4
Exceptional
1,003 reviews
9.2
Wonderful
264 reviews
9.2
Wonderful
1,265 reviews
The price is ￥39,369
￥53,439 total
includes taxes & fees
Oct 30 - Oct 31
The price is ￥14,665
￥17,343 total
includes taxes & fees
Nov 15 - Nov 16
The price is ￥26,433
￥34,092 total
includes taxes & fees
Nov 20 - Nov 21
The price is ￥13,817
￥16,166 total
includes taxes & fees
Nov 4 - Nov 5
The price is ￥25,428
￥31,650 total
includes taxes & fees
Nov 8 - Nov 9
  • No Breakfast included
  • Yes, Pool
  • Yes, Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • No Pool
  • No Spa
  • No Pet friendly
  • Yes, WiFi included
  • Yes, Parking
  • No Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet friendly
  • No WiFi included
  • Yes, Parking

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Sentral Forme Houston

Sentral Forme Houston

10/10 Excellent
"Very clean, room w/kirchen, friendly and helpful staff, awesome gym, walking distance to museums. Loved it!"
Francisco 1-night trip
Posted 4 hours ago
Sentral Forme Houston

Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1272 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden, and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops to visit in the neighborhood. Daikin Park and Toyota Center are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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