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Our top choices for South Central Houston hotels
The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictSouth Central Houston
9.2 out of 10, Wonderful, (1,153 reviews)
"Fantastic reasonably priced property."
William
The price is ￥23,690
￥29,487 total
includes taxes & fees
May 22 - May 23
Sentral Forme Houston
Sentral Forme HoustonSouth Central Houston
9.2 out of 10, Wonderful, (27 reviews)
"Verry nice and staff was very helpful. Will stay again"
Carolyn
The price is ￥26,479
￥35,563 total
includes taxes & fees
May 31 - Jun 1
Downtowner Inns - Houston Downtown
Downtowner Inns - Houston DowntownSouth Central Houston
8.6 out of 10, Excellent, (141 reviews)
"The staff is so unbelievably friendly. The room is clean & worth it"
Marcisha
The price is ￥13,537
￥15,839 total
includes taxes & fees
May 10 - May 11
Hotel Zaza Houston Museum District
Hotel Zaza Houston Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,016 reviews)
"It was a wonderful place to stay will be coming back again."
Jesse
The price is ￥31,632
￥44,123 total
includes taxes & fees
May 25 - May 26
InterContinental Houston by IHG
InterContinental Houston by IHGSouth Central Houston
9.2 out of 10, Wonderful, (1,009 reviews)
"The food was excellent and the staff friendly and helpful. "
Andrea
The price is ￥25,225
￥32,647 total
includes taxes & fees
May 25 - May 26
Hilton Houston Plaza/Medical Center
Hilton Houston Plaza/Medical CenterSouth Central Houston
8.4 out of 10, Very Good, (1,906 reviews)
"A clean and spacious room and parking area available."
Benigna
The price is ￥14,516
￥17,166 total
includes taxes & fees
May 25 - May 26
Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictSouth Central Houston
9.0 out of 10, Wonderful, (1,003 reviews)
"Right in the center of the Medical District. Didn’t even have to go outside to get to my wife’s appointment. "
Dominick
The price is ￥28,061
￥37,925 total
includes taxes & fees
May 22 - May 23
Americas Best Value Inn Medical Center Downtown
Americas Best Value Inn Medical Center DowntownSouth Central Houston
8.0 out of 10, Very Good, (1,011 reviews)
"Convenient location and comfortable room."
Rogelio
The price is ￥11,586
￥13,554 total
includes taxes & fees
May 13 - May 14
La Maison in Midtown an urban B&B
La Maison in Midtown an urban B&BSouth Central Houston
9.8 out of 10, Exceptional, (571 reviews)
"We felt welcome from the moment we walked in. The owners are so hospitable and the place such a delight. Loved the generous breakfast and ambiance- great parking as well!"
Carolina
The price is ￥24,681
￥28,877 total
includes taxes & fees
May 17 - May 18
DoubleTree by Hilton Houston Medical Center Hotel & Suites
DoubleTree by Hilton Houston Medical Center Hotel & SuitesSouth Central Houston
8.4 out of 10, Very Good, (576 reviews)
"Staff was wonderful "
Lynn
The price is ￥16,769
￥19,621 total
includes taxes & fees
May 17 - May 18
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults OnlySouth Central Houston
9.6 out of 10, Exceptional, (212 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
Shelly
The price is ￥32,433
￥40,297 total
includes taxes & fees
May 14 - May 15
Wanderstay Boutique Hotel
Wanderstay Boutique HotelSouth Central Houston
9.8 out of 10, Exceptional, (72 reviews)
"Solo trip and it was a perfect location staff was nice and it was nice and clean!! Would stay there again. "
Sharon
The price is ￥18,858
￥22,065 total
includes taxes & fees
May 12 - May 13
Paradise Palace Best Rooftop in HTX w Hot Tub
Paradise Palace Best Rooftop in HTX w Hot TubSouth Central Houston
The price is ￥46,596
￥108,594 total
includes taxes & fees
May 21 - May 22
Southmore Boulevard Motel
Southmore Boulevard MotelSouth Central Houston
5.6 out of 10, (238 reviews)
"I enjoyed my stay at this hotel."
Tamela
The price is ￥8,793
￥10,288 total
includes taxes & fees
May 11 - May 12
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Extended Stay America Suites Houston Med Ctr Braeswood BlSouth Central Houston
5.8 out of 10, (1,013 reviews)
"Love the pet friendly property"
Nelda
The price is ￥11,279
￥13,241 total
includes taxes & fees
May 17 - May 18
Hilton University of Houston
Hilton University of HoustonSouth Central Houston
9.0 out of 10, Wonderful, (940 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
Ricardo
The price is ￥21,595
￥25,267 total
includes taxes & fees
May 21 - May 22
Golden Motel Near Houston Medical Center
Golden Motel Near Houston Medical CenterSouth Central Houston
2.0 out of 10, (1 review)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
Jacari
The price is ￥8,187
￥10,398 total
includes taxes & fees
May 10 - May 11
Wanderstay Houston Hostel
Wanderstay Houston HostelSouth Central Houston
8.2 out of 10, Very Good, (200 reviews)
"it was a great experience, staff was kind and helpful. "
James
The price is ￥9,567
￥11,192 total
includes taxes & fees
May 10 - May 11
Houston 6 Bedroom Home
Houston 6 Bedroom HomeSouth Central Houston
The price is ￥155,346
￥264,068 total
includes taxes & fees
May 16 - May 17
Posh Dtwn Midtown Home w Stunning Roof-topterrace
Posh Dtwn Midtown Home w Stunning Roof-topterraceSouth Central Houston
The price is ￥29,723
￥98,589 total
includes taxes & fees
Jun 2 - Jun 3
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in South Central Houston
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Wanderstay Boutique Hotel | 9.8 Exceptional 72 reviews | View | ||||||
 The Westin Houston Medical Center/Museum District | 9.2 Wonderful 1,153 reviews | View | ||||||
 Sentral Forme Houston | 9.2 Wonderful 27 reviews | View | ||||||
 InterContinental Houston by IHG | 9.2 Wonderful 1,009 reviews | View | ||||||
 Hilton University of Houston | 9.0 Wonderful 940 reviews | View |
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Downtown Houston
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Top South Central Houston Hotel Reviews
Extended Stay America Suites Houston Med Ctr Braeswood Bl
8/10 Good
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