Find Hotels with Early Check-in in South Main, TX
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on South Main Hotels with Early Check-in
Our top choices for South Main hotels with express check-in
1. Quality Inn & Suites NRG Park - Medical Center
Quality Inn & Suites NRG Park - Medical CenterSouth Main
6.6 out of 10, (1,013 reviews)
"Excellent customer service."
Olavo
The price is ￥9,791
￥11,456 total
includes taxes & fees
Aug 27 - Aug 28
2. Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHG
Holiday Inn Express & Suites Houston S - Medical Ctr Area by IHGBraeswood Place
9.4 out of 10, Exceptional, (1,003 reviews)
"My stay was great"
Cheryl
The price is ￥17,974
￥21,158 total
includes taxes & fees
Aug 11 - Aug 12
8.4 out of 10, Very Good, (1,541 reviews)
"Great staff, good breakfast and room in good condition"
Bruno
The price is ￥12,565
￥15,488 total
includes taxes & fees
Aug 12 - Aug 13
4. Holiday Inn Houston S - Nrg Area - Medical Center by IHG
Holiday Inn Houston S - Nrg Area - Medical Center by IHGAstrodome
8.2 out of 10, Very Good, (1,002 reviews)
"Great location, also very clean hotel.!"
Aldalberto
The price is ￥15,294
￥17,894 total
includes taxes & fees
Aug 13 - Aug 14
8.4 out of 10, Very Good, (2,093 reviews)
"Brilliant location and pool"
Daniel
The price is ￥13,050
￥15,451 total
includes taxes & fees
Aug 16 - Aug 17
6. The Westin Houston Medical Center/Museum District
The Westin Houston Medical Center/Museum DistrictTexas Medical Center
9.2 out of 10, Wonderful, (1,178 reviews)
"Clean and friendly staff"
Bernadine
The price is ￥22,649
￥28,191 total
includes taxes & fees
Sep 6 - Sep 7
7. Houston Marriott Medical Center/Museum District
Houston Marriott Medical Center/Museum DistrictTexas Medical Center
9.0 out of 10, Wonderful, (1,004 reviews)
"I enjoyed my stay!"
Valencia
The price is ￥22,563
￥31,420 total
includes taxes & fees
Aug 7 - Aug 8
8. DoubleTree by Hilton Hotel Houston - Greenway Plaza
DoubleTree by Hilton Hotel Houston - Greenway PlazaGreenway Plaza-Upper Kirby
8.4 out of 10, Very Good, (1,793 reviews)
"Excellent place to stay with family"
Fahad
The price is ￥12,800
￥14,976 total
includes taxes & fees
Aug 14 - Aug 15
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top South Main Hotel Reviews
Explore a world of travel with Expedia
- Downtown Houston Hotels
- Inns in Houston
- Cheap Hotels in Greater Third Ward
- Hotels near Texas Southern University
- Hotels near Menil Collection
- All-Inclusive Hotel Hotels in East Downtown Houston
- Hotels near Toyota Center
- Family Hotels in South Central Houston
- Beach Hotels in Houston Central Business District
- Historic Hotels in Texas Medical Center
- Hotels near NRG Center
- Guest Houses in Houston
- Boutique Hotels in East Downtown Houston
- Hotels near MD Anderson Cancer Center
- Hotels near Greater Houston Convention and Visitors Bureau
- Adults Only Resorts & in Texas Medical Center
- Shopping Hotels in Texas Medical Center
- Houston Convention District Hotels
- Hotels with an Indoor Pool in Greater Uptown
- B&B in Houston
- Hotels near Houston Station
- Cheap Hotels in The Galleria
- Cheap Hotels in Downtown Houston
- Greater Third Ward Hotels
- Hotels near Greenway Plaza
- Hotels with smoking rooms in Greater Uptown
- Greater Uptown Hotels
- Cheap Hotels in Texas Medical Center
- Hotels near Houston Arboretum and Nature Center
- Rice Village Hotels
- Boutique Hotels in Greenway Plaza-Upper Kirby
- Hotels near Alley Theater
- 5 Star Hotels in Houston
- Hotel with a Concierge Hotels in Braeswood Place
- Luxury Hotels in Downtown Houston
- Hotels with Early Check-in in The Galleria
- Town Houses in Houston
- Apartments in Bellaire
- Hotels near Houston Natural Science Museum
- Motels in Memorial Hermann Hospital/Houston Zoo Station
- Uptown Hotels
- Adults Only Resorts & in Houston
- Apartments in Houston
- Hotels near River Oaks District
- Business Hotels in The Galleria
- Harris County Hotels
- East Downtown Houston Hotels
- Ryokans in Houston
- Hotels near Rice University
- Hotels near University of Houston - Downtown
- Hotels with Free Parking in The Galleria
- Boutique Hotels in The Galleria
- Houston Hotels
- Hotels near University of St. Thomas
- Missouri City Hotels
- Hotels near NRG Stadium
- Hotels near Jesse H. Jones Hall
- Hotels with an Indoor Pool in Houston
- Historic Hotels in Houston
- Hotels near River Oaks Country Club
- Hotels near University of Houston
- Hotels near Uptown Park
- Hotels near Rothko Chapel
- Shopping Hotels in Braeswood Place
- Hotels near Pearland Town Center
- Hotels near George R. Brown Convention Center
- Capsule Hotels in Houston
- Ranches in Houston
- Waterpark Hotels in Houston
- University Place Hotels
- Hotels near Houston Museum of Fine Arts
- Cheap Hotels in Theater District
- Hotels near Shops at Houston Center
- Hotels near NRG Park
- Pet-Friendly Hotels in The Galleria
- Luxury Hotels in Braeswood Place
- All-Inclusive Hotel Hotels in Houston
- River Oaks Hotels
- Hotels near Houston City Hall
- Hotels near Transco Tower Heliport
- Motels in Southwest Houston
- Hotels near House of Blues Houston
- Hotels near Sam Houston Park
- Hotels near The Galleria
- Montrose Hotels
- Hotels near Saint Arnold Brewery
- Hotels near Main Street Theater - Rice Village
- Treehouses in Houston
- The Galleria Hotels
- Golf Hotels in Greater Uptown
- Hotels near Rice Stadium
- Hotels near Richmond Avenue
- Hotels near Houston Contemporary Arts Museum
- Texas Medical Center Hotels
- Hotels near Market Square Park
- Hotels near NRG Astrodome