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Jul 3 - Jul 5
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Jul 10 - Jul 12

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Our top choices for South Central Houston hotels

Terrace/patio

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.4 out of 10, Very Good, (1,981 reviews)
"Great stay and clean room"
United States
Ethel
The price is ￥20,864
￥24,601 total
includes taxes & fees
Jul 5 - Jul 6
Hilton Houston Plaza/Medical Center
Dinner served

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,002 reviews)
"This hotel has incredible staff"
United States
Susanne
The price is ￥24,601
￥33,961 total
includes taxes & fees
Jul 10 - Jul 11
Houston Marriott Medical Center/Museum District
Outdoor pool, free cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,153 reviews)
"The best hotel! Location/ pool/ fitness/ comfortable beds: beautiful views"
United States
Jennifer Noel
The price is ￥23,161
￥28,828 total
includes taxes & fees
Jul 5 - Jul 6
The Westin Houston Medical Center/Museum District
Laptop workspace, blackout drapes, soundproofing, iron/ironing board

Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (183 reviews)
"Great place. The staff is very friendly and the place is clean."
United States
Fernando
The price is ￥13,571
￥15,879 total
includes taxes & fees
Jul 5 - Jul 6
Downtowner Inns - Houston Downtown
Exterior detail

Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
8.8 out of 10, Excellent, (60 reviews)
"Amazing stay!!"
Canada
Elizabeth
The price is ￥27,334
￥36,713 total
includes taxes & fees
Jul 7 - Jul 8
Sentral Forme Houston
Exterior

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,003 reviews)
"Was a over great place to stay"
United States
Danny
The price is ￥24,584
￥31,998 total
includes taxes & fees
Jul 26 - Jul 27
InterContinental Houston by IHG
Premium bedding, pillowtop beds, minibar, in-room safe

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,004 reviews)
"Great place to stay"
United States
Gayathry
The price is ￥32,384
￥45,215 total
includes taxes & fees
Jul 6 - Jul 7
Hotel Zaza Houston Museum District
Breakfast, lunch and dinner served

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (615 reviews)
"was ok"
United States
Guillermo
The price is ￥19,802
￥23,169 total
includes taxes & fees
Jul 12 - Jul 13
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Reception

Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very Good, (1,004 reviews)
"Great AC, Clean room, would stay again"
United States
Haylie
The price is ￥16,012
￥18,733 total
includes taxes & fees
Jul 5 - Jul 6
Americas Best Value Inn Medical Center Downtown
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
5.8 out of 10, (1,007 reviews)
"Love the pet friendly property"
United States
Nelda
The price is ￥13,099
￥15,371 total
includes taxes & fees
Jul 8 - Jul 9
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (954 reviews)
"The hotel was clean, staff were friendly and the location was perfect for our event. I will definitely stay there again. "
United States
Ricardo
The price is ￥23,538
￥27,540 total
includes taxes & fees
Jul 7 - Jul 8
Hilton University of Houston
House | 2 bedrooms

Modern 2BR Home With King Beds Near Downtown

Modern 2BR Home With King Beds Near Downtown
2.0 star property
South Central Houston
The price is ￥14,030
￥98,061 total
includes taxes & fees
Jul 1 - Jul 2
Modern 2BR Home With King Beds Near Downtown
Standard Room, 1 King Bed | 1 bedroom, premium bedding, blackout drapes, free WiFi

Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.6 out of 10, (241 reviews)
"I enjoyed my stay at this hotel."
United States
Tamela
The price is ￥11,069
￥12,952 total
includes taxes & fees
Jun 30 - Jul 1
Southmore Boulevard Motel
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (214 reviews)
"Beautiful place and wonderful management. Would definitely stay again! "
United States
Shelly
The price is ￥33,480
￥41,598 total
includes taxes & fees
Jul 1 - Jul 2
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Reception

Golden Motel Near Houston Medical Center

Golden Motel Near Houston Medical Center
2.5 star property
South Central Houston
2.0 out of 10, (4 reviews)
"Room smelt like cigarettes burnt wholes in the wall and bed sheet all 6 walls had stains toilet seat look like someone stood on it "
United States
Jacari
The price is ￥10,513
￥13,352 total
includes taxes & fees
Jul 7 - Jul 8
Golden Motel Near Houston Medical Center
Apartment (2 Bedrooms) | Interior

Walkable Eado Condo Near Dtwn: Modern + Chic!

Walkable Eado Condo Near Dtwn: Modern + Chic!
3.0 star property
South Central Houston
Walkable Eado Condo Near Dtwn: Modern + Chic!
Exterior

La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (585 reviews)
"Beautiful stay with wonderful hosts! Highly recommended!"
Canada
CEDRIC AUGUSTINE DE
The price is ￥25,853
￥30,248 total
includes taxes & fees
Jul 6 - Jul 7
La Maison in Midtown an urban B&B
Full-size fridge, microwave, oven, stovetop

Luxury Med Center Fully Equipped King Sized Bed Condos

Luxury Med Center Fully Equipped King Sized Bed Condos
4.0 star property
South Central Houston
8.4 out of 10, Very Good, (92 reviews)
"Facility was nice. DRIFTRS, the management company, is really bad. We were there for 4 days. Upon arrival we noticed no toilet paper and half the light bulbs burned out. The place was so dark I needed a flashlight to use the kitchen. We reported these issues immediately. They told us to use kitchen paper towels as toilet paper and did not respond to all the burned out light bulbs. We woke up every morning with the apartment hot and stuffy. The NEST thermostat is programmed to continually...
United States
Gordon
The price is ￥23,671
￥43,061 total
includes taxes & fees
Jul 6 - Jul 7
Luxury Med Center Fully Equipped King Sized Bed Condos
Free WiFi, bed sheets

MorningSide Inn

MorningSide Inn
2.0 star property
South Central Houston
6.0 out of 10, (521 reviews)
"The staff is very friendly and responsive. We needed some help after check in and they fulfilled all quickly and in a friendly manner. The room was clean. There is no fan. A/C was good but a fan in the sitting area would be good. The bathroom was clean but old looking. The hotel is in a nice neighborhood and it was peaceful and safe. I stayed there with my family for the world cup match. The stadium was very near. We had a peaceful stay and its very value for the money"
United States
Anand
The price is ￥12,131
￥14,194 total
includes taxes & fees
Jul 1 - Jul 2
MorningSide Inn
Interior

Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very Good, (207 reviews)
"Excellent stay experience"
United States
Binkeung
The price is ￥9,876
￥11,553 total
includes taxes & fees
Jul 6 - Jul 7
Wanderstay Houston Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Exterior
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
585 reviews
View
Laptop workspace, blackout drapes, soundproofing, iron/ironing board
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
183 reviews
View
Outdoor pool
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
214 reviews
View
Outdoor pool, free cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District
4.0 star property
9.2
Wonderful
1,153 reviews
View
Exterior
InterContinental Houston by IHG
4.0 star property
9.2
Wonderful
1,003 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
A cityscape with modern skyscrapers and a park with trees and people.

Downtown Houston

Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.

A large, modern shopping mall with a glass ceiling and multiple levels.

The Galleria

Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.

A cityscape with tall buildings, including a prominent one with 'Texas Children's Hospital' on it, under a partly cloudy sky.

Texas Medical Center

Boasting the world's largest medical complex, this Houston neighborhood offers access to over 60 medical institutions and is served by the METRORail Red Line. Explore the John P. McGovern Historical Collections and Research Center for a unique experience.

An art gallery with a minimalist design, featuring a central bench and large abstract paintings on the walls.

Montrose

Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

8/10 Good
"The hotel was very conveniently located in the Medical District and hotel offered shuttles every 30 min to hospitals. Room was clean and comfortable."
Lee 3-night trip
Posted 8 hours ago
Hilton Houston Plaza/Medical Center

Frequently asked questions

What's it like in South Central Houston?
Travelers are sure to enjoy a stay in Houston's South Central Houston neighborhood. Be sure to check out TDECU Stadium and Fertitta Center as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveler data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and InterContinental Houston by IHG.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1235 hotels and other accommodations in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to review the best options available in South Central Houston.
Where can I learn more about changing or cancelling my trip to South Central Houston?
To access more information about changing or cancelling your trip to South Central Houston, go to https://www.expedia.com/service/.
What is there to do around this Houston neighborhood?
Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape, and Cullen Sculpture Garden. TDECU Stadium and Fertitta Center are some other stops to visit in the neighborhood. Toyota Center and Daikin Park are some favorite places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station, or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.

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