Top 10 Hotels in Commerce, MO from ￥10,332 - Competitive Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Commerce

Pet friendly

Apartment

Pool

Condo

Family friendly

Waterpark

Cabin

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Commerce hotels

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A Drury Plaza Hotel with a modern design, featuring a prominent entrance, multiple floors, and a clear sky.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

1. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Matthew

￥15,893

￥17,929 total

includes taxes & fees

Sep 20 - Sep 21

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

￥16,213

￥18,291 total

includes taxes & fees

Sep 22 - Sep 23

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

3. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Bonnie

￥11,443

￥12,909 total

includes taxes & fees

Aug 31 - Sep 1

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

A spacious dining area with high tables and chairs, a bar counter, and large windows providing natural light.

4. Drury Inn & Suites Sikeston, MO

Sikeston

Sally

￥14,953

￥17,191 total

includes taxes & fees

Aug 30 - Aug 31

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

5. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

￥16,814

￥18,968 total

includes taxes & fees

Sep 2 - Sep 3

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

￥14,727

￥15,939 total

includes taxes & fees

Sep 2 - Sep 3

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

7. The Riverview

Cape Girardeau

Alyssa

￥16,896

￥19,061 total

includes taxes & fees

Aug 31 - Sep 1

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

A restaurant with multiple tables and chairs, an exit sign, a television, and a counter with food items.

8. Quality Inn Cape Girardeau North

Cape Girardeau

Stephen

￥9,814

￥11,072 total

includes taxes & fees

Sep 20 - Sep 21

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel room with a kitchenette, a bed, a desk, and a TV.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A modern living room with a sofa, a coffee table, a blue armchair, and a desk with a lamp. A kitchen area with wooden cabinets and a microwave is visible in the background.

9. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

￥13,988

￥16,654 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

A reception area with a counter, a flat-screen TV, and a window with blinds.

10. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

France

￥9,458

￥10,496 total

includes taxes & fees

Sep 20 - Sep 21

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

11. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Heather

￥16,078

￥18,139 total

includes taxes & fees

Sep 3 - Sep 4

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A spacious living room with a sofa set, a coffee table, and a dining area.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

12. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Taylor

￥20,600

￥23,343 total

includes taxes & fees

Sep 3 - Sep 4

A modern retail area with a display of local items and snacks.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

13. Tru By Hilton Cape Girardeau

Cape Girardeau

Gwendolyn

￥14,207

￥16,169 total

includes taxes & fees

Sep 21 - Sep 22

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A breakfast setting with waffles, scrambled eggs, toast, a glass of orange juice, and a white mug on a table with a green placemat.

14. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Cheryl

￥14,304

￥16,138 total

includes taxes & fees

Sep 2 - Sep 3

A building with a fountain and flower beds in front.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A hotel room with a beige sofa, two patterned armchairs, a ceiling fan, a flat-screen TV, and a window with curtains.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

15. The Riverstone Hotel Charleston-Sikeston

Charleston

Bobby

￥10,569

￥11,728 total

includes taxes & fees

Sep 21 - Sep 22

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

16. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

￥13,276

￥14,368 total

includes taxes & fees

Sep 23 - Sep 24

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

A Quality Inn hotel with a green sign, a covered outdoor area, and a parking lot.

A hotel room with a desk, chair, television, and a lamp.

17. Quality Inn Cairo I-57

Cairo

Sharon

￥11,444

￥12,700 total

includes taxes & fees

Aug 31 - Sep 1

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

18. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

￥11,127

￥12,998 total

includes taxes & fees

Sep 9 - Sep 10

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

A motel with a sign reading "Eagle Inn" and a parking lot with several cars.

19. Eagle Inn Charleston

Charleston

Jackson

￥11,023

￥12,234 total

includes taxes & fees

Aug 26 - Aug 27

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A reception area with a counter, a coffee machine, and seating.

A bathroom with a bathtub, toilet, and shower curtain.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

20. Country Yard Inn and Suite

Sikeston

William

￥8,683

￥10,332 total

includes taxes & fees

Sep 16 - Sep 17

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Commerce Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent

"A very nice hotel with good dinner and breakfast. Nice big rooms with comfortable chairs and giant TV!"

Tru By Hilton Cape Girardeau

10/10 Excellent

"We had a great stay at Tru in Cape. The hotel was clean, comfortable, and the staff made everything easy. The only thing missing was having microwaves in the rooms — adding those would make the experience even better."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"The staff at the location were very accommodating. Check to make sure everything was good. The breakfast was awesome. I was concerned that the pool was being under construction and that was not sent out to people that are planning or had planned to stay there. I was looking forward to the pool and if have been a hot tub."

Courtyard by Marriott Cape Girardeau Downtown

8/10 Good

"Hotel was nice, my bathroom felt a bit outdated. Outside of that it was a great stay"

The Riverview

8/10 Good

"Nice view of the river. The staff was nice."

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"Great value, very clean and breakfast was actually good."

Town House Inn Cape Giradreau

10/10 Excellent

"If your looking for a budget friendly hotel to stay that is clean or if you need a place to call home for a month till you find a place, I highly recommend this hotel."

Super 8 by Wyndham Charleston/Sikeston East MO

10/10 Excellent

"Nice staff. Very accommodating."

Hampton Inn Cape Girardeau I 55 East

10/10 Excellent

"Good Job!"

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

￥9,458

￥10,496 total

Sep 20 - Sep 21

includes taxes & fees

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

￥9,814

￥11,072 total

Sep 20 - Sep 21

includes taxes & fees

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

￥11,443

￥12,909 total

Aug 31 - Sep 1

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

￥14,207

￥16,169 total

Sep 21 - Sep 22

includes taxes & fees

9.6/10 Exceptional! (172 reviews)

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

￥13,988

￥16,654 total

Aug 30 - Aug 31

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

￥16,213

￥18,291 total

Sep 22 - Sep 23

includes taxes & fees

Frequently asked questions

What's the best place to stay in Commerce?

Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay based on our traveler data. Two other options for your trip to the area are The Riverview and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Commerce.

What are some of the best vacation home rentals in Commerce?

"Brickyard"-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau: This vacation home near Commerce is located on a river and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. See all vacation rentals in Commerce.

If I need to cancel my hotel reservation in Commerce, will I receive a refund?

Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.

Where can I learn more about changing or cancelling my trip to Commerce?

To find more details about rescheduling or cancelling your trip to Commerce, go to https://www.expedia.com/service/.

What's it like to stay in Commerce?

Travelers to Commerce will find plenty to explore and enjoy. There are 84 hotels and other accommodations in the surrounding area. Find out more about Commerce.

What is there to see in Commerce?

A favorite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Check out what more to see and do in Expedia's Commerce guide.

What's the weather like in Commerce?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Commerce is 59 inches.

Explore a world of travel with Expedia

Car rentals near New Madrid County

Book Hotels in Commerce on Expedia.com

Find hotels in Commerce, MO from ￥10,332

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Commerce

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Commerce hotels

1. Drury Plaza Hotel Cape Girardeau Conference Center

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3. Pear Tree Inn Cape Girardeau West

4. Drury Inn & Suites Sikeston, MO

5. Hampton Inn Cape Girardeau I 55 East

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

7. The Riverview

8. Quality Inn Cape Girardeau North

9. Candlewood Suites Cape Girardeau by IHG

10. Super 8 by Wyndham Charleston/Sikeston East MO

11. Fairfield Inn & Suites by Marriott Cape Girardeau

12. Courtyard by Marriott Cape Girardeau Downtown

13. Tru By Hilton Cape Girardeau

14. Drury Inn & Suites Cape Girardeau

15. The Riverstone Hotel Charleston-Sikeston

16. Comfort Suites Jackson-Cape Girardeau

17. Quality Inn Cairo I-57

18. Town House Inn Cape Giradreau

19. Eagle Inn Charleston

20. Country Yard Inn and Suite

Top Commerce Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Tru By Hilton Cape Girardeau

Drury Inn & Suites Cape Girardeau

Courtyard by Marriott Cape Girardeau Downtown

The Riverview

Drury Inn & Suites Sikeston, MO

Town House Inn Cape Giradreau

Super 8 by Wyndham Charleston/Sikeston East MO

Hampton Inn Cape Girardeau I 55 East

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app