Top 10 Hotels in Advance, MO from ￥9,121 - Competitive Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Advance

Pet friendly

Apartment

Pool

Condo

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Advance hotels

A living room with a blue wall, a fireplace, a sofa, and a chair.

A brick building with a sign reading "Mercantile & Hotel".

A sign for EC REED'S MERCANTILE & HOTEL with a geometric design.

A hotel room with two beds, a vanity with a mirror, a chair, and a dresser.

1. EC Reed's Mercantile and Hotel

Marble Hill

JANEEN

￥16,601

￥18,070 total

includes taxes & fees

Oct 11 - Oct 12

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

Rebecca

￥15,948

￥18,151 total

includes taxes & fees

Oct 25 - Oct 26

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A reception desk with a large mural of a bridge, wooden reception area, and a potted plant.

A hotel room with two beds, a nightstand, a lamp, and a chair.

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

￥12,750

￥13,800 total

includes taxes & fees

Nov 1 - Nov 2

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

4. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Curtis

￥15,788

￥17,811 total

includes taxes & fees

Oct 13 - Oct 14

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

A Fairfield by Marriott hotel with a modern design, featuring a stone facade, multiple floors, and a well-lit entrance.

5. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

￥15,972

￥18,018 total

includes taxes & fees

Oct 15 - Oct 16

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A modern dining area with wooden tables and chairs, a kitchen area with a tiled backsplash, and framed pictures on the wall.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

6. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

￥11,367

￥12,824 total

includes taxes & fees

Oct 25 - Oct 26

A Hampton Inn with a stone facade, outdoor seating area, and a fire pit.

An indoor swimming pool with lounge chairs, a lifeguard stand, and large windows offering a view of the outside.

A conference room with a large rectangular table, six chairs with patterned upholstery, two modern ceiling lights, a bowl of fruit on the table, and large windows with curtains.

A hotel lobby with a bar area, seating arrangements, and a large window providing natural light.

7. Hampton Inn Sikeston

Sikeston

Carolyn

￥16,643

￥18,928 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A hotel room with two beds, a desk, a chair, and a view of the city.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

8. The Riverview

Cape Girardeau

Alyssa

￥15,882

￥17,917 total

includes taxes & fees

Oct 22 - Oct 23

A spacious lobby with a large sectional sofa, multiple armchairs, and a coffee table. There is a TV mounted on the wall and a large window providing a view of the outdoors.

A Drury Inn & Suites building with a traditional architectural style, featuring a covered entrance and multiple windows.

A hotel room with two beds, a brick wall, and a wooden headboard.

An indoor swimming pool with a wooden ceiling, lounge chairs, and a lifeguard chair.

9. Drury Inn & Suites Jackson MO

Jackson

Debra S

￥12,630

￥13,353 total

includes taxes & fees

Oct 14 - Oct 15

A modern retail area with a display of local items and snacks.

A modern indoor seating area with blue sofas and tables, a patterned carpet, and large windows offering a view of the outdoors.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

10. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

￥14,113

￥16,062 total

includes taxes & fees

Oct 22 - Oct 23

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A lobby with seating areas, a reception desk, and a bar.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

11. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

￥19,753

￥22,383 total

includes taxes & fees

Oct 23 - Oct 24

A hotel room with two beds, a desk with a chair, a TV, and a window with curtains.

A buffet with various food items, including omelets and baked goods, served in metal containers.

A kitchenette with a coffee machine, a kettle, and storage shelves.

A Holiday Inn Express & Suites building with a covered entrance, multiple windows, and a parking lot.

12. Holiday Inn Express & Suites Sikeston Southwest by IHG

Sikeston

￥14,369

￥16,341 total

includes taxes & fees

Nov 8 - Nov 9

A modern hotel with a sign reading "Towneplace Suites by Marriott Fairfield." It features a flat roof, large windows, and a well-lit entrance.

A modern hotel room with a large window, a gray sofa, a small round table, a white chair, and a bed.

A modern lobby with a green sofa, two armchairs, a wooden coffee table, and a patterned rug.

13. TownePlace Suites by Marriott Sikeston

Sikeston

Stacy

￥15,971

￥18,164 total

includes taxes & fees

Oct 18 - Oct 19

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A room with large windows, two red upholstered chairs, a small table, and a potted plant.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

14. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

￥11,945

￥12,927 total

includes taxes & fees

Nov 1 - Nov 2

An outdoor seating area with a circular fire pit surrounded by chairs, a covered patio, and a building with large windows in the background.

An outdoor bar area with a modern design, featuring a counter, seating, and a view of the interior.

A modern indoor swimming pool with clear glass walls, a tiled deck, and multiple lounge chairs.

A modern hotel building with a sign reading "TOWNPLACE SUITES BY MARRIOTT" and "Fairfield BY MARRIOTT".

15. Fairfield Inn & Suites by Marriott Sikeston

Sikeston

Allen

￥15,948

￥18,137 total

includes taxes & fees

Oct 18 - Oct 19

A modern hotel lobby with a bar area, seating, and artwork on the walls.

A modern kitchen with a large island, bar stools, wine bottles, and a built-in TV.

A modern hotel with a prominent sign, a covered entrance, and a well-lit exterior.

A reception desk with a wooden panel design, a white vase with flowers, and a 'Hilton HONOR' sign.

16. Hampton Inn By Hilton Dexter

Dexter

￥15,408

￥17,455 total

includes taxes & fees

Oct 18 - Oct 19

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

An outdoor patio with stone walls, wicker furniture, and large windows.

A large indoor swimming pool with clear blue water, surrounded by tiled flooring and blue walls.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

17. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

￥16,703

￥18,844 total

includes taxes & fees

Oct 18 - Oct 19

A hotel room with a bed, a desk, a chair, a bathroom with a bathtub, and a patterned floor.

A kitchen with wooden cabinets, a stainless steel sink, a microwave, and a dishwasher.

A hotel with a brick facade, multiple windows, and a covered entrance area.

A hotel reception area with a reception desk, framed certificates, and a painting on the wall.

18. Econo Lodge Dexter

Dexter

￥8,051

￥9,121 total

includes taxes & fees

Nov 7 - Nov 8

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

19. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

￥14,367

￥16,208 total

includes taxes & fees

Nov 8 - Nov 9

A kitchen with dark wooden cabinets, a stainless steel refrigerator, a black stove, a microwave, and a sink.

A bathroom with a granite countertop sink, a mirror, two hair dryers mounted on the wall, and a trash bin.

A trophy labeled "Town House Inn" with "Cape Girardeau County, Missouri" and "2025" on it.

20. Town House Inn

Jackson

￥11,004

￥11,909 total

includes taxes & fees

Oct 13 - Oct 14

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Advance Hotel Reviews

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"The whole experience here during our stay was wonderful. Staff was friendly, everything was clean and well maintained. We would definitely stay here again."

Hampton Inn Sikeston

10/10 Excellent

"Loved the modern, CLEAN, room and staff was extremely friendly and helpful. We were greeted and served by "Brittany" at check-in who was so nice and friendly and even gave us dinner suggestions. We would definitely stay here again!"

Quality Inn Cape Girardeau North

8/10 Good

"Clean rooms, nice staff"

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent

"Nice property"

Drury Inn & Suites Jackson MO

10/10 Excellent

"We were only there for one night, but we SO grateful for a clean, safe and lovely stay! Would recommend it highly!"

Candlewood Suites Cape Girardeau by IHG

8/10 Good

"I usually stay here if I need to because I travel back and forth from northern IL and I usually have a lot of food to take home to southern MS. The full size fridge and freezer is very nice to have available and you don’t have to book a super fancy room to get one. Housekeeping can be hard work, but missing a rather large blood stain on the wall behind the door is disturbing. Thankfully I always travel with Lysol wipes and cleaned it up."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Charming 3-bedroom house in delightful Advance with AC, WiFi

10/10 Excellent

"The house was so charming! It was immaculate! It had all the amenities needed. Lots of parking area and great neighborhood. Communication with our wonderful host was so prompt! We hope to stay there again!!"

More cheap stays in Advance

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

￥11,367

￥12,824 total

Oct 25 - Oct 26

includes taxes & fees

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

￥14,113

￥16,062 total

Oct 22 - Oct 23

includes taxes & fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

￥13,579

￥16,187 total

Nov 8 - Nov 9

includes taxes & fees

8/10 Very Good! (1,000 reviews)

Holiday Inn Express & Suites Sikeston Southwest by IHG

115 Hospitality Dr Sikeston MO

￥14,369

￥16,341 total

Nov 8 - Nov 9

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

￥15,948

￥18,151 total

Oct 25 - Oct 26

includes taxes & fees

9.4/10 Exceptional! (1,000 reviews)

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO

￥16,643

￥18,928 total

Oct 18 - Oct 19

includes taxes & fees

9/10 Wonderful! (632 reviews)

Frequently asked questions

Where is the best place to stay in Advance?

Based on Expedia's traveler preferences, Private Getaway on 270 Acres w/ Lake: Swim & Canoe is a top place to stay in Advance. Two other options for your trip to the area are Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Advance.

What are some of the best vacation rentals that Advance has to offer?

3 Bed 3 Bath Beautiful Historic District Within Walking Downtown Cape Girardeau: This vacation home rental outside of Advance is equipped with a barbecue grill, air-conditioning, and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a fridge, and a stovetop. See all vacation rentals in Advance.

If I need to cancel my hotel reservation in Advance, will I receive a refund?

Yes! The majority of hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Advance.

Where can I learn more about changing or cancelling my trip to Advance?

To access more information about changing or cancelling your trip to Advance, go to https://www.expedia.com/service/.

How is it to stay in Advance?

Travelers to Advance will find plenty to explore and enjoy. In Advance, there are 3 hotels and other accommodations to choose from. Find out more about Advance.

What is there to see in Advance?

Places to visit in the wider area include Bollinger Mill State Historic Site, Mingo Wilderness, and Stoddard County Civil War Memorial Cemetery. Check out what more to see and do in Expedia's Advance guide.

What's the weather like in Advance?

The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Advance is 59 inches.

Find hotels in Advance, MO from ￥9,121

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Advance

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Advance hotels

1. EC Reed's Mercantile and Hotel

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

4. Drury Plaza Hotel Cape Girardeau Conference Center

5. Fairfield Inn & Suites by Marriott Cape Girardeau

6. Pear Tree Inn Cape Girardeau West

7. Hampton Inn Sikeston

8. The Riverview

9. Drury Inn & Suites Jackson MO

10. Tru By Hilton Cape Girardeau

11. Courtyard by Marriott Cape Girardeau Downtown

12. Holiday Inn Express & Suites Sikeston Southwest by IHG

13. TownePlace Suites by Marriott Sikeston

14. Comfort Suites Jackson-Cape Girardeau

15. Fairfield Inn & Suites by Marriott Sikeston

16. Hampton Inn By Hilton Dexter

17. Hampton Inn Cape Girardeau I 55 East

18. Econo Lodge Dexter

19. Drury Inn & Suites Cape Girardeau

20. Town House Inn

Top Advance Hotel Reviews

Drury Inn & Suites Cape Girardeau

Hampton Inn Sikeston

Quality Inn Cape Girardeau North

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Drury Inn & Suites Jackson MO

Candlewood Suites Cape Girardeau by IHG

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

Charming 3-bedroom house in delightful Advance with AC, WiFi

More cheap stays in Advance

Pear Tree Inn Cape Girardeau West

Tru By Hilton Cape Girardeau

Candlewood Suites Cape Girardeau by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hampton Inn Sikeston

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app