Find hotels in St. Charles, MN from ¥8,148

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Our top choices for St. Charles hotels

1. Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,000 reviews)
"Great stay"
United States
Susan
The price is ¥15,380
¥17,708 total
includes taxes & fees
Dec 12 - Dec 13
Hampton Inn Rochester-South

2. AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
3.0 star property
Winona
9.0 out of 10, Wonderful, (1,000 reviews)
"Always stay when in the area, great staff and clean rooms."
United States
Jonathan
The price is ¥20,102
¥22,438 total
includes taxes & fees
Nov 16 - Nov 17
AmericInn by Wyndham Winona

3. Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,000 reviews)
"Nice location, easy access and good breakfast."
United States
Rick
The price is ¥15,338
¥17,657 total
includes taxes & fees
Dec 11 - Dec 12
Holiday Inn Express Rochester South - Mayo Area by IHG

4. Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (607 reviews)
"Clean room Staff very accommodating Hot coffee and breakfast."
United States
Stanton
The price is ¥10,729
¥12,351 total
includes taxes & fees
Nov 22 - Nov 23
Spark by Hilton Rochester South

5. La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.6 out of 10, Good, (1,063 reviews)
"Nice place!"
United States
Joseph
The price is ¥10,864
¥12,506 total
includes taxes & fees
Nov 15 - Nov 16
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

6. Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,010 reviews)
"Great place to stay."
United States
LeeAnn
The price is ¥12,002
¥13,817 total
includes taxes & fees
Dec 11 - Dec 12
Comfort Inn & Suites Rochester South Mayo Clinic

7. Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,007 reviews)
"Great stay."
Canada
Robert Blaise
The price is ¥17,766
¥20,453 total
includes taxes & fees
Nov 27 - Nov 28
Hyatt House Rochester/Mayo Clinic Area

8. Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,011 reviews)
"Clean room and breakfast area was very clean."
United States
Britta
The price is ¥10,722
¥12,345 total
includes taxes & fees
Dec 12 - Dec 13
Econo Lodge Mayo Clinic Area

9. Stone Mill Hotel & Suites

Stone Mill Hotel & Suites
3.0 star property
Lanesboro
9.6 out of 10, Exceptional, (731 reviews)
"Very unique property with cozy, comfortable accommodations."
United States
Bernie
The price is ¥16,666
¥17,896 total
includes taxes & fees
Nov 15 - Nov 16
Stone Mill Hotel & Suites

10. Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,002 reviews)
"Our stay was very nice"
United States
Anne
The price is ¥19,046
¥21,927 total
includes taxes & fees
Nov 14 - Nov 15
Brentwood Inn & Suites

11. AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.2 out of 10, Very good, (1,610 reviews)
"Great stay, we were only there for one night, but the staff was very nice and helpful!"
United States
Madelyn
The price is ¥11,583
¥13,335 total
includes taxes & fees
Dec 6 - Dec 7
AmericInn by Wyndham Rochester Near Mayo Clinic

12. TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (577 reviews)
"This location is awesome if you are going to Mayo Clinic. What an easy walk to the clinic. Several great restaurants are also within walking distance."
United States
Neil
The price is ¥21,745
¥25,035 total
includes taxes & fees
Dec 12 - Dec 13
TownePlace Suites by Marriott Rochester Mayo Clinic Area

13. Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
Rochester
9.6 out of 10, Exceptional, (321 reviews)
"Clean hotel, friendly staff, great location."
United States
Chee
The price is ¥21,090
¥24,280 total
includes taxes & fees
Nov 27 - Nov 28
Residence Inn by Marriott Rochester Mayo Clinic Area South

14. Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.4 out of 10, Exceptional, (1,001 reviews)
"Clean room, very nice staff and nice atmosphere."
United States
howard
The price is ¥17,404
¥20,038 total
includes taxes & fees
Dec 13 - Dec 14
Home2 Suites by Hilton Rochester Mayo Clinic Area

15. Fairfield Inn & Suites by Marriott Winona

Fairfield Inn & Suites by Marriott Winona
3.0 star property
Winona
9.4 out of 10, Exceptional, (422 reviews)
"The pool and breakfast were both great!"
United States
Leanne
The price is ¥21,284
¥23,759 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott Winona

16. Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (657 reviews)
"Clean rooms, great staff, convenient location."
United States
Jennifer
The price is ¥27,025
¥31,113 total
includes taxes & fees
Nov 27 - Nov 28
Hilton Rochester Mayo Clinic Area

17. Quality Inn & Suites Mayo Clinic Area

Quality Inn & Suites Mayo Clinic Area
2.5 star property
Rochester
8.8 out of 10, Excellent, (973 reviews)
"Nice location, staff very helpful and friendly, and nice big room"
United States
Mark
The price is ¥11,054
¥12,899 total
includes taxes & fees
Dec 4 - Dec 5
Quality Inn & Suites Mayo Clinic Area

18. Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very good, (1,000 reviews)
"clean room, great breakfast and nice we can walk to bar and grill for dinner at night."
United States
jill
The price is ¥15,743
¥18,124 total
includes taxes & fees
Nov 16 - Nov 17
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

19. Comfort Inn & Suites West - Medical Center

Comfort Inn & Suites West - Medical Center
3.0 star property
Rochester
8.8 out of 10, Excellent, (670 reviews)
"The room was very clean and the beds were comfortable. Breakfast was good with lots of options."
United States
Tammy
The price is ¥13,139
¥15,125 total
includes taxes & fees
Dec 11 - Dec 12
Comfort Inn & Suites West - Medical Center

20. SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
Kutzky Park
8.6 out of 10, Excellent, (1,000 reviews)
"Clean rooms & nice breakfast"
United States
Jackie
The price is ¥16,285
¥18,748 total
includes taxes & fees
Dec 6 - Dec 7
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

Frequently Asked Questions

What's the top vacation rental in St. Charles?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: This vacation home rental outside of St. Charles offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind. See all vacation rentals in St. Charles.

If I need to cancel my hotel reservation in St. Charles, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.

Where can I learn more about changing or cancelling my trip to St. Charles?

To access more information about updating your trip to St. Charles or cancelling it, go to https://www.expedia.com/service/.

Where is the best hotel to stay near Whitewater State Park?

White Valley Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 6.4 mi (10.3 km) from Whitewater State Park. Other good choices around the area include Kahler Inn and Suites - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S.

What's the best hotel for staying near Rochester International Airport (RST)?

AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.

What's it like staying in St. Charles?

Visitors can enjoy all that St. Charles has to offer including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodations to choose from. Find out more about St. Charles.

What is there to see in St. Charles?

A couple of favorite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Check out what more to see and do in Expedia's St. Charles guide.

What's the seasonal weather like in St. Charles?

The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.

Where is the best place to stay in St. Charles?

AmericInn by Wyndham Rochester Near Mayo Clinic, located 20.5 mi (32.9 km) from the heart of St. Charles, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.

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