An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for St. Charles vacation rentals

A wooden cabin with a porch, two chairs, and a door.

1. Tiny Treehouse Cabin | Bluff Woodlands #2

Tiny Treehouse Cabin | Bluff Woodlands #2
Elba
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
The price is ￥18,515
￥30,083 total
includes taxes & fees
Sep 29 - Sep 30
Tiny Treehouse Cabin | Bluff Woodlands #2
A covered deck with outdoor seating, surrounded by a forested area.

2. Tiny Treehouse Cabin | Bluff Woodlands #3

Tiny Treehouse Cabin | Bluff Woodlands #3
Elba
10.0 out of 10, Exceptional, (13 reviews)
"My family of 4 had a wonderful stay!"
United States
Josh S.
The price is ￥20,214
￥31,912 total
includes taxes & fees
Sep 29 - Sep 30
Tiny Treehouse Cabin | Bluff Woodlands #3
A wooden cabin with a porch, two chairs, and a door.

3. Three Treehouse Cabins in the Bluff Woodlands

Three Treehouse Cabins in the Bluff Woodlands
Elba
The price is ￥58,942
￥84,086 total
includes taxes & fees
Sep 29 - Sep 30
Three Treehouse Cabins in the Bluff Woodlands
A two-story house with a covered patio and a pathway leading to the entrance.

4. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (165 reviews)
"An excellent place to stay! Clean, private, safe and beautiful neighborhood. "
United States
Brandi B.
The price is ￥14,155
￥27,162 total
includes taxes & fees
Sep 29 - Sep 30
Magical Nest Hideaway
A backyard with a picnic table, string lights, and a wooden fence.

5. Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay

Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
East Side Pioneers
The price is ￥9,751
￥19,664 total
includes taxes & fees
Oct 2 - Oct 3
Rose’s Barnhouse Loft | Cozy Farm-Inspired Stay
A dining room with a white table, white chairs, a chandelier, and a potted plant.

6. Discounted Charming 2-bedroom main-level TRIPLEX in Rochester

Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
East Side Pioneers
9.4 out of 10, Exceptional, (22 reviews)
"The place was great"
United States
Michelle L.
The price is ￥11,324
￥31,144 total
includes taxes & fees
Oct 6 - Oct 7
Discounted Charming 2-bedroom main-level TRIPLEX in Rochester
A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

7. The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (443 reviews)
"Excellent service and wonderful room!"
United States
Suzette
The price is ￥28,310
￥32,917 total
includes taxes & fees
Oct 2 - Oct 3
The Berkman
A living room with a dark brown sofa, two trash bins, a framed artwork of an artichoke, and a lamp on a side table.

8. Across from St Marys hospital Covered By Faith 2

Across from St Marys hospital Covered By Faith 2
Kutzky Park
8.0 out of 10, Very good, (2 reviews)
"Easy check in/ Secure entry system "
United States
Ann R.
The price is ￥8,808
￥25,360 total
includes taxes & fees
Sep 29 - Sep 30
Across from St Marys hospital Covered By Faith 2
Two wooden cabins elevated on stilts in a forest, with outdoor seating and hammocks.

9. Tiny Treehouse Cabin | Bluff Woodlands #1

Tiny Treehouse Cabin | Bluff Woodlands #1
Elba
9.6 out of 10, Exceptional, (10 reviews)
"Great area a place to stay. "
United States
Paul T.
The price is ￥20,214
￥31,912 total
includes taxes & fees
Sep 29 - Sep 30
Tiny Treehouse Cabin | Bluff Woodlands #1
A row of stacked front-loading washing machines in a laundry room with a tiled floor.

10. Suite w/ Kitchen + Breakfast | Near Mayo Clinic

Suite w/ Kitchen + Breakfast | Near Mayo Clinic
Rochester
The price is ￥22,806
￥30,547 total
includes taxes & fees
Oct 4 - Oct 5
Suite w/ Kitchen + Breakfast | Near Mayo Clinic
A small brick building with a sign reading 'WYKOFF JAIL HOUSE.'

11. Wykoff Historical Jail Haus with Original Jail Cell Bunks.

Wykoff Historical Jail Haus with Original Jail Cell Bunks.
Wykoff
10.0 out of 10, Exceptional, (5 reviews)
"Phenomenal communication with Becky, our host. Will be coming to this property again. It is unique and unlike anything I ever stayed at before. It was a jail in its former life after all. Very authentic with a modern twist. Great place!!!"
United States
Peggy
The price is ￥14,863
￥19,338 total
includes taxes & fees
Oct 5 - Oct 6
Wykoff Historical Jail Haus with Original Jail Cell Bunks.
A living room with a television displaying a scenic view, a dark armchair, a sofa, and a wooden coffee table.

12. 2 steps entry 1mile to Mayo CoveredByFaith Inspire

2 steps entry 1mile to Mayo CoveredByFaith Inspire
Parkway
10.0 out of 10, Exceptional, (3 reviews)
"Great pet friendly option"
United States
Erik G.
The price is ￥13,054
￥41,668 total
includes taxes & fees
Oct 1 - Oct 2
2 steps entry 1mile to Mayo CoveredByFaith Inspire
A kitchen with white cabinets, a sink, and a coffee maker.

13. Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Rochester
9.4 out of 10, Exceptional, (33 reviews)
"This was a very clean and cozy property."
United States
Angela O.
The price is ￥13,369
￥34,767 total
includes taxes & fees
Oct 7 - Oct 8
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
A compact living space with a dining area, kitchenette, and a seating area with a sofa and chairs.

14. Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!

Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
Rochester
10.0 out of 10, Exceptional, (11 reviews)
"It was amazing stay, it was very comfy, welcoming and definitely something we would book again!!"
United States
Jessica Z.
The price is ￥14,155
￥39,474 total
includes taxes & fees
Sep 29 - Sep 30
Discounted 5-Star 3 Bedroom Duplex 5 Minutes to Mayo Clinic!
A modern living room with a brown leather sofa, a white armchair, a coffee table, and a dining area with a table and chairs.

15. The June | Private 1br Basement Apt, Pets Welcome!

The June | Private 1br Basement Apt, Pets Welcome!
Rochester
10.0 out of 10, Exceptional, (7 reviews)
"This place was quiet, comfortable, well-stocked, and incredibly close to everything we were looking for. The hosts were great communicators, and accessing the place was a snap."
United States
Josh P.
The price is ￥14,155
￥33,500 total
includes taxes & fees
Oct 1 - Oct 2
The June | Private 1br Basement Apt, Pets Welcome!
A living room with a flat-screen TV on a wooden stand, a gray sofa, and a blue armchair.

16. Close to Mayo/Shops, 1 step entry Covered By Faith

Close to Mayo/Shops, 1 step entry Covered By Faith
Rochester
9.8 out of 10, Exceptional, (13 reviews)
"The host was so incredibly responsive whenever we had questions, the house was incredibly clean and welcoming, and we enjoyed our stay there."
United States
Anonymous traveler
The price is ￥17,144
￥46,540 total
includes taxes & fees
Oct 1 - Oct 2
Close to Mayo/Shops, 1 step entry Covered By Faith
A living room with a television, sofa, coffee table, and shelves with decorative items.

17. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
The price is ￥21,233
￥33,010 total
includes taxes & fees
Sep 29 - Sep 30
Vintage Lustron Home Piece of History
A residential building with a dark blue front door, a small porch with a metal railing, and a brick facade.

18. Across from St Marys hospital Covered By Faith 1

Across from St Marys hospital Covered By Faith 1
Kutzky Park
4.0 out of 10, (1 review)
The price is ￥8,808
￥25,360 total
includes taxes & fees
Oct 1 - Oct 2
Across from St Marys hospital Covered By Faith 1
A modern apartment with a staircase, a dining area, and a living space.

19. Charming 3-bedroom, 2 bathroom house with outdoor space in Winona

Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
Winona
10.0 out of 10, Exceptional, (33 reviews)
"A charming place to stay with a spacious primary bedroom, laundry room, and living areas. The backyard patio is a perfect place for a morning coffee and a quiet evening. We would definitely rebook on our next visit."
United States
Mainul
The price is ￥36,804
￥42,998 total
includes taxes & fees
Sep 29 - Sep 30
Charming 3-bedroom, 2 bathroom house with outdoor space in Winona
A compact RV kitchen with wooden cabinets, a stove, and a dining area with a bench.

20. Big River Escape Coyote Camper #1

Big River Escape Coyote Camper #1
Buffalo City
10.0 out of 10, Exceptional, (2 reviews)
"Awesome as usual "
United States
Matthew B.
The price is ￥18,559
￥22,898 total
includes taxes & fees
Sep 29 - Sep 30
Big River Escape Coyote Camper #1
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top St. Charles Hotel Reviews

Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

10/10 Excellent
"Friendly staff, quiet environment. My son particularly liked the pool."
Bookman 1-night trip
Posted 5 hours ago
Express Suites Riverport Inn & Suites

Find out more about St. Charles

Search for holiday rentals in St. Charles on Expedia! You can easily find your home rentals, villas, holiday apartments in St. Charles using one of the methods below:

  • View our selection of featured holiday rentals in St. Charles
  • Use the map to find apartments and other holiday homes in the St. Charles neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in St. Charles while they last

Look no further and take a look at our great range of rental properties in St. Charles!

Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.