An aerial view of a town with industrial buildings, roads, and green areas.

Find hotels in St. Charles, MN from ¥11,394

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Property class

Our top choices for St. Charles hotels

Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN
2.0 star property
Winona
7.8 out of 10, Good, (1,003 reviews)
"Clean, good location, friendly staff. Decent quick breakfast options, but could use a little more variety. Overall a good stay!"
United States
Joshua
The price is ¥10,028
¥11,394 total
includes taxes & fees
Jul 26 - Jul 27
Super 8 by Wyndham Winona MN

Days Inn by Wyndham Winona

Days Inn by Wyndham Winona
2.0 star property
Winona
7.8 out of 10, Good, (1,001 reviews)
"My room was very nice very clean and it was an exceptional stay"
United States
Twila
The price is ¥12,227
¥13,648 total
includes taxes & fees
Jul 2 - Jul 3
Days Inn by Wyndham Winona

Comfort Inn & Suites Rochester South Mayo Clinic

Comfort Inn & Suites Rochester South Mayo Clinic
2.0 star property
Rochester
8.8 out of 10, Excellent, (1,005 reviews)
"Really like this hotel!"
United States
Stephanie
The price is ¥13,172
¥15,163 total
includes taxes & fees
Jul 30 - Jul 31
Comfort Inn & Suites Rochester South Mayo Clinic

Baymont by Wyndham Rochester Mayo Clinic Area

Baymont by Wyndham Rochester Mayo Clinic Area
2.5 star property
Rochester
7.0 out of 10, Good, (804 reviews)
"Very nice stay."
United States
Tramisha
The price is ¥9,625
¥11,080 total
includes taxes & fees
Jul 5 - Jul 6
Baymont by Wyndham Rochester Mayo Clinic Area

MainStay Suites Rochester South Mayo Clinic

MainStay Suites Rochester South Mayo Clinic
2.5 star property
Rochester
7.2 out of 10, Good, (120 reviews)
"This was a nice place to stay especially for the price!! I would recommend."
United States
Brian
The price is ¥9,898
¥11,396 total
includes taxes & fees
Jul 12 - Jul 13
MainStay Suites Rochester South Mayo Clinic

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
3.0 star property
Rochester
7.4 out of 10, Good, (1,064 reviews)
"Breakfast was just like any other hotel."
United States
LOIS
The price is ¥12,955
¥14,915 total
includes taxes & fees
Jul 5 - Jul 6
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Birch Hill Suite Rochester – Med City

Birch Hill Suite Rochester – Med City
2.5 star property
Rochester
7.2 out of 10, Good, (47 reviews)
"The staff and room was great! "
United States
Cheryl
The price is ¥9,387
¥10,807 total
includes taxes & fees
Jun 30 - Jul 1
Birch Hill Suite Rochester – Med City

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic
2.0 star property
Rochester
7.8 out of 10, Good, (1,002 reviews)
"Our room was very clean. The hotel itself only so-so. The continental breakfast was quite nice!"
United States
Johanna
The price is ¥11,273
¥12,977 total
includes taxes & fees
Jul 12 - Jul 13
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

AmericInn by Wyndham Winona

AmericInn by Wyndham Winona
3.0 star property
Winona
9.0 out of 10, Wonderful, (950 reviews)
"Very clean, wonderful pool area and very good breakfast."
United States
Jacob
The price is ¥19,934
¥22,252 total
includes taxes & fees
Jul 23 - Jul 24
AmericInn by Wyndham Winona

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
2.5 star property
Kutzky Park
8.0 out of 10, Very Good, (1,010 reviews)
"Good place to stay"
United States
Janet
The price is ¥12,227
¥14,076 total
includes taxes & fees
Jun 30 - Jul 1
Med City Inn & Suites - Mayo Clinic Area

Quality Inn near Medical Center

Quality Inn near Medical Center
2.5 star property
Rochester
7.8 out of 10, Good, (916 reviews)
"Stayed with our softball team and front desk staff was friendly and helpful. "
United States
Crystal
The price is ¥10,861
¥12,503 total
includes taxes & fees
Jul 21 - Jul 22
Quality Inn near Medical Center

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,369 reviews)
"Everything was great! Enjoyed our stay."
United States
Karen
The price is ¥12,786
¥14,720 total
includes taxes & fees
Jul 12 - Jul 13
AmericInn by Wyndham Rochester Near Mayo Clinic

Super 8 by Wyndham Rochester Mayo Clinic Area

Super 8 by Wyndham Rochester Mayo Clinic Area
2.0 star property
Rochester
7.8 out of 10, Good, (1,001 reviews)
"Enjoyed my stay"
United States
Guled
The price is ¥8,799
¥10,130 total
includes taxes & fees
Jul 12 - Jul 13
Super 8 by Wyndham Rochester Mayo Clinic Area

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,003 reviews)
"Great experience, would definitely stay again!!"
United States
Mike
The price is ¥15,331
¥17,650 total
includes taxes & fees
Jul 30 - Jul 31
Hampton Inn Rochester-South

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (958 reviews)
"Great place"
United States
Shayn
The price is ¥12,810
¥14,748 total
includes taxes & fees
Jul 12 - Jul 13
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice place for the value. I would stay again."
United States
Dominic
The price is ¥11,280
¥12,986 total
includes taxes & fees
Jul 26 - Jul 27
Econo Lodge Mayo Clinic Area

Extended Stay America Suites Rochester North

Extended Stay America Suites Rochester North
2.5 star property
Rochester
7.6 out of 10, Good, (711 reviews)
"Clean, comfortable and easy checkin "
United States
Jean
The price is ¥11,061
¥12,733 total
includes taxes & fees
Jun 30 - Jul 1
Extended Stay America Suites Rochester North

Holiday Inn Express Rochester South - Mayo Area by IHG

Holiday Inn Express Rochester South - Mayo Area by IHG
2.5 star property
Rochester
8.8 out of 10, Excellent, (1,003 reviews)
"Room was clean, nice shower, and the breakfast was tasty with good variety."
United States
Nicole
The price is ¥16,174
¥18,620 total
includes taxes & fees
Jul 3 - Jul 4
Holiday Inn Express Rochester South - Mayo Area by IHG

Spark by Hilton Rochester South

Spark by Hilton Rochester South
3.0 star property
Rochester
9.2 out of 10, Wonderful, (516 reviews)
"Spacious clean room. Located near restaurants and shopping."
United States
BARBARA
The price is ¥11,930
¥13,735 total
includes taxes & fees
Jul 6 - Jul 7
Spark by Hilton Rochester South

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (717 reviews)
"Great location close to St. Marys. The hotel is nice, coffee is good, and overall a nice place to stay."
United States
Brian
The price is ¥19,247
¥22,157 total
includes taxes & fees
Jul 3 - Jul 4
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about St. Charles

St. Charles awaits: its natural setting and more!

An aerial view of a town with industrial buildings, roads, and green areas.

Top St. Charles Hotel Reviews

More cheap stays in St. Charles

Frequently asked questions

Where is the best place to stay in St. Charles?
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area, located 20.7 mi (33.3 km) from the heart of St. Charles, is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Kahler Grand Hotel and Kahler Inn and Suites - Mayo Clinic Area. See all available top hotels, or vacation rentals in St. Charles.
What's the top vacation rental in St. Charles?
The Hen House Retreat - A Comfortable Place to Roost: This vacation home rental outside of St. Charles is located in a rural location and has a fireplace, a patio, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You can relax into your vacation with a garden and a selection of games. See all vacation rentals in St. Charles.
If I need to cancel my hotel reservation in St. Charles, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in St. Charles.
Where can I learn more about changing or cancelling my trip to St. Charles?
To access more information about updating your trip to St. Charles or cancelling it, go to https://www.expedia.com/service/.
Where is the best hotel to stay near Whitewater State Park?
White Valley Motel is one of the top choices for your stay based on our traveler data, and this property offers free parking and free WiFi. You'll find it 6.4 mi (10.3 km) from Whitewater State Park. Other good choices around the area include Kahler Inn and Suites - Mayo Clinic Area and La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S.
What's the best hotel for staying near Rochester International Airport (RST)?
AmericInn by Wyndham Rochester Airport is a popular hotel, featuring free breakfast and an indoor pool. It's located a short 0.6 mi (1 km) from Rochester Intl. Airport. Other choices near the airport include La Quinta Inn & Suites by Wyndham Rochester and Comfort Suites.
What's it like staying in St. Charles?
Visitors can enjoy all that St. Charles has to offer including its parks. This city also attracts tourists with its welcoming locals. In St. Charles, there are 3 hotels and other accommodations to choose from. Find out more about St. Charles.
What is there to see in St. Charles?
A couple of favorite places to visit are Whitewater State Park and Whitewater River. You'll also find Regional Sports Center and National Volleyball Center in the area. Check out what more to see and do in Expedia's St. Charles guide.
What's the seasonal weather like in St. Charles?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 22°F. The snowiest months in St. Charles are January, March, February, and April, with each month seeing an average of 8 inches of snowfall.