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Compare hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Rochester Mayo Clinic Area
3.5 star property
9.6 out of 10, Exceptional, (527)
"Best stay in downtown Rochester in years. "
United States
Anita
The price is ¥26,307
¥30,286 total
includes taxes & fees
Dec 6 - Dec 7
Hilton Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (468)
"Overall great place"
United States
Jill
The price is ¥15,256
¥17,564 total
includes taxes & fees
Nov 29 - Nov 30
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
9.6 out of 10, Exceptional, (665)
"Very clean, friendly staff, great breakfast selection"
United States
Daniel
The price is ¥15,043
¥17,318 total
includes taxes & fees
Dec 7 - Dec 8
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (359)
"Amazing place to stay right across from St Marys Hospital. "
United States
Kemberly
The price is ¥17,336
¥20,157 total
includes taxes & fees
Nov 23 - Nov 24
The Berkman
Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
9.6 out of 10, Exceptional, (864)
"Staff was welcoming and polite. Room was clean and comfortable."
United States
Lisa
The price is ¥17,876
¥20,579 total
includes taxes & fees
Nov 16 - Nov 17
Home2 Suites by Hilton Rochester Mayo Clinic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
9.6 out of 10, Exceptional, (233)
"Great place"
United States
Steve
The price is ¥19,571
¥22,531 total
includes taxes & fees
Nov 20 - Nov 21
Residence Inn by Marriott Rochester Mayo Clinic Area South
EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
9.4 out of 10, Exceptional, (929)
"This is a very nice hotel. "
United States
paul
The price is ¥17,499
¥20,453 total
includes taxes & fees
Nov 7 - Nov 8
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
9.4 out of 10, Exceptional, (413)
"Nice place to stay for any reason but if you’re going to Mayo clinic, it’s very convenient"
United States
Jerome
The price is ¥19,034
¥22,221 total
includes taxes & fees
Dec 6 - Dec 7
Staybridge Suites Rochester - Mayo Clinic Area by IHG
The Towers At Kahler Grand Hotel
4.0 star property
9.4 out of 10, Exceptional, (90)
"Great breakfast "
United States
PAMELA
The price is ¥54,833
¥63,127 total
includes taxes & fees
Nov 9 - Nov 10
The Towers At Kahler Grand Hotel
Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
9.4 out of 10, Exceptional, (445)
"Convenient location "
United States
Tammy
The price is ¥14,948
¥17,209 total
includes taxes & fees
Nov 24 - Nov 25
Candlewood Suites Rochester Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.2 out of 10, Wonderful, (1000)
"Clean hotel with a good breakfast close to Mayo Clinic "
United States
Ashley
The price is ¥19,802
¥22,796 total
includes taxes & fees
Nov 15 - Nov 16
Hyatt House Rochester/Mayo Clinic Area
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2 out of 10, Wonderful, (166)
"I would highly recommend this property to anyone it is very clean and well maintained and the apartments have pretty amazing views of downtown overall amazing "
United States
Trenton
The price is ¥23,577
¥27,143 total
includes taxes & fees
Nov 29 - Nov 30
Broadway Plaza, Trademark Collection by Wyndham
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
9.2 out of 10, Wonderful, (469)
"I love staying at Homewood Suites"
United States
linda
The price is ¥14,670
¥16,889 total
includes taxes & fees
Nov 30 - Dec 1
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
9.0 out of 10, Wonderful, (754)
"It's a very good hotel where you can spend every day comfortably."
Japan
Makoto
The price is ¥16,026
¥18,451 total
includes taxes & fees
Nov 14 - Nov 15
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Aspen Suites
3.0 star property
9.0 out of 10, Wonderful, (676)
"Excellent service excellent accommodations. I will stay here again when I come next time."
United States
Ryan
Aspen Suites
Hampton Inn Rochester-South
2.5 star property
9.0 out of 10, Wonderful, (1001)
"Great hotel,!"
United States
Cheryl
The price is ¥12,598
¥14,504 total
includes taxes & fees
Nov 28 - Nov 29
Hampton Inn Rochester-South
Econo Lodge Mayo Clinic Area
2.0 star property
9.0 out of 10, Wonderful, (862)
"Liked our stay!"
United States
Troy
The price is ¥10,295
¥11,853 total
includes taxes & fees
Dec 6 - Dec 7
Econo Lodge Mayo Clinic Area
Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
8.8 out of 10, Excellent, (857)
"Room was great and staff was very friendly and helpful "
United States
shane
The price is ¥9,708
¥11,177 total
includes taxes & fees
Nov 28 - Nov 29
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Brentwood Inn & Suites
2.5 star property
8.8 out of 10, Excellent, (1002)
"Nice comfy "
United States
Steve
The price is ¥17,336
¥19,957 total
includes taxes & fees
Nov 7 - Nov 8
Brentwood Inn & Suites
Hilton Garden Inn Rochester Downtown, MN
3.0 star property
8.8 out of 10, Excellent, (828)
"Very friendly, helpful staff. Lovely environment and location."
United States
Kayla
The price is ¥16,429
¥18,913 total
includes taxes & fees
Nov 15 - Nov 16
Hilton Garden Inn Rochester Downtown, MN
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mayo Clinic Hotel Reviews

Hotels near other Mayo Clinic attractions

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 157 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 157 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

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