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Find hotels in Southwest Illinois, IL from ￥7,598

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Dec 12 - Dec 13
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Dec 13 - Dec 14
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Dec 12 - Dec 14
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Dec 19 - Dec 21

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Our top choices for Southwest Illinois hotels

Lobby
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

Comfort Suites Mount Vernon
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1005)
"Rooms have been painted great breakfast close to interstate and restaurants"
United States
Stephen
The price is ￥16,111
￥18,192 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Suites Mount Vernon
Lobby lounge
Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1568)
"Great place to stay. Check in is easy and the hotel people are very nice."
United States
Duane
The price is ￥14,615
￥16,531 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Plaza Hotel Mt. Vernon
Exterior
Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG

Holiday Inn Express & Suites Mount Vernon by IHG
2.5 star property
Mount Vernon
9.0 out of 10, Wonderful, (1002)
"Great stay"
United States
Cindy
The price is ￥14,772
￥16,706 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Holiday Inn Express & Suites Mount Vernon by IHG
Lobby
SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake

SureStay Hotel by Best Western Whittington Rend Lake
2.5 star property
Whittington
8.8 out of 10, Excellent, (903)
"Great place to stay."
United States
Stephen
The price is ￥11,233
￥12,466 total
includes taxes & fees
Dec 31 - Jan 1, 2026
SureStay Hotel by Best Western Whittington Rend Lake
Lobby
Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57

Comfort Inn & Suites Marion I-57
2.5 star property
Marion
9.4 out of 10, Exceptional, (1002)
"Very clean room, friendly staff, and the breakfast was tasty. Will stay there again"
United States
Marcus
The price is ￥16,793
￥20,149 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Comfort Inn & Suites Marion I-57
Lobby sitting area
Baymont by Wyndham Marion

Baymont by Wyndham Marion

Baymont by Wyndham Marion
2.5 star property
Marion
8.4 out of 10, Very Good, (1066)
"This place was nice for the money and our 1 night stay. "
United States
Charles
The price is ￥11,392
￥13,668 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Baymont by Wyndham Marion
Free daily buffet breakfast
Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel

Best Western Plus MidAmerica Hotel
2.5 star property
Mascoutah
9.0 out of 10, Wonderful, (1002)
"Great hotel stay with nice hot breakfast options"
Canada
John
The price is ￥17,034
￥19,415 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus MidAmerica Hotel
Room, 1 Queen Bed, Accessible, Non Smoking | Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL

Super 8 by Wyndham Mt. Vernon IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (1005)
"reception was great, room clean, and the price was right."
United States
tom
The price is ￥10,356
￥11,804 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super 8 by Wyndham Mt. Vernon IL
In-room safe, desk, iron/ironing board, cribs/infant beds
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1001)
"Awesome place to stay. Clean room, comfortable bed, amenities were accommodating, plenty of restaurants near by to choose from, and near the highway."
United States
Evelyn
The price is ￥10,550
￥11,498 total
includes taxes & fees
Dec 14 - Dec 15
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Free continental breakfast
Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL

Quality Inn Mount Vernon, IL
2.5 star property
Mount Vernon
7.8 out of 10, Good, (536)
"It was nice and clean. It was a great place to just stop and sleep. The staff was very friendly, and it was located next to a lot of places to eat"
United States
Christopher
The price is ￥10,590
￥12,065 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn Mount Vernon, IL
Free daily full breakfast
Best Western Marion Hotel

Best Western Marion Hotel

Best Western Marion Hotel
2.5 star property
Marion
8.2 out of 10, Very Good, (1001)
"Friendly staff"
United States
Brent
The price is ￥10,434
￥12,518 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Best Western Marion Hotel
Indoor pool, outdoor pool
Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL

Drury Inn & Suites St. Louis O'Fallon, IL
3.0 star property
O'Fallon
9.6 out of 10, Exceptional, (1002)
"Excellent location, clean and spacious room, great morning breakfast with numerous choices and of course helpful and pleasant staff."
United States
David
The price is ￥15,858
￥18,392 total
includes taxes & fees
Dec 21 - Dec 22
Drury Inn & Suites St. Louis O'Fallon, IL
Exterior
Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG

Holiday Inn Express Hotel & Suites Marion Northeast by IHG
2.5 star property
Marion
9.0 out of 10, Wonderful, (925)
"yes the room was great and the staff was great! "
United States
Amador
The price is ￥15,083
￥18,096 total
includes taxes & fees
Jan 10 - Jan 11, 2026
Holiday Inn Express Hotel & Suites Marion Northeast by IHG
Lobby
Drury Inn & Suites Marion

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1002)
"Hotel is very clean and staff is also friendly."
United States
Tonya
The price is ￥10,105
￥12,125 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Drury Inn & Suites Marion
Lobby
Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (808)
"Staffing was awesome and helpful. "
United States
Warren
The price is ￥9,912
￥10,803 total
includes taxes & fees
Dec 14 - Dec 15
Ramada by Wyndham Vandalia
Lobby
Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70

Comfort Inn & Suites Greenville I-70
2.5 star property
Greenville
8.4 out of 10, Very Good, (415)
"Room was clean and comfortable."
United States
Michael
The price is ￥14,095
￥15,643 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Comfort Inn & Suites Greenville I-70
Reception
Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites

Best Western Plus Centralia Hotel & Suites
2.5 star property
Centralia
9.6 out of 10, Exceptional, (600)
"Very beautiful place to stay "
United States
Valerie
The price is ￥18,752
￥20,998 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Plus Centralia Hotel & Suites
Lobby
Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL

Country Inn & Suites by Radisson, Marion, IL
2.5 star property
Marion
8.6 out of 10, Excellent, (1000)
"Room was nice and staff was friendly."
United States
MING
The price is ￥15,067
￥18,077 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Country Inn & Suites by Radisson, Marion, IL
Classic Room, 1 King Bed | Desk, free WiFi, bed sheets
Powhatan Motel

Powhatan Motel

Powhatan Motel
2.5 star property
Pocahontas
8.6 out of 10, Excellent, (192)
"Clean, updated bathroom, easy parking, great breakfast."
United States
Cheryl
The price is ￥15,044
￥15,944 total
includes taxes & fees
Dec 15 - Dec 16
Powhatan Motel
Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace
Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon
2.0 star property
O'Fallon
7.2 out of 10, Good, (1003)
"Staff were very friendly. It was clean & quiet. I will definitely stop again on my next trip. "
United States
Julian
The price is ￥6,608
￥7,598 total
includes taxes & fees
Dec 21 - Dec 22
Super 8 by Wyndham O'Fallon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southwest Illinois, IL

Showing deals for:Dec 19 - Dec 21

Image gallery for Red Bud Country Inn

Desk, laptop workspace, blackout drapes, iron/ironing board

Red Bud Country Inn

2.5 star property
Red Bud
9.0/10Wonderful (51 reviews)
10% off
Price is ￥11,934
￥26,489 total
includes taxes & fees
Red Bud Country Inn
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Stay near popular Central United States attractions

Marion Cultural and Civic Center

3.9/5 (34 reviews)
Marion Cultural and Civic Center is just one of the places to see in Marion, so why not enjoy the other things to explore during your travels? While you're here, you can savor the top-notch restaurants.
See properties

O'Fallon Family Sports Park

4.2/5 (51 reviews)
Explore the great outdoors at O'Fallon Family Sports Park, a lovely green space in O'Fallon. Check out the shops and top-notch restaurants in this family-friendly area.
See properties

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove
Photo by Carl Anderson
Open Photo by Carl Anderson

Top Southwest Illinois Hotel Reviews

Quality Inn & Suites near St. Louis and I-255

Quality Inn & Suites near St. Louis and I-255

10/10 Excellent
"Great value."
Todd 5-night trip
Posted 19 hours ago
Quality Inn & Suites near St. Louis and I-255

More cheap stays in Southwest Illinois

Super 8 by Wyndham O'Fallon

Super 8 by Wyndham O'Fallon

1100 Eastgate Dr O'Fallon IL
The price is ￥6,608 per night from Dec 21 to Dec 22
￥6,608
￥7,598 total
Dec 21 - Dec 22
includes taxes & fees
7/10 Good! (1,001 reviews)

Hotels in Southwest Illinois with star-rating

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