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Compare 1,073 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (141)
"Perfect stay! "
The price is ¥14,998
¥16,645 total
includes taxes & fees
Sep 24 - Sep 25
The Principal Hotel

Best Western Plus Parkside Inn & Suites

2.5 star property
9.8 out of 10, Exceptional, (303)
"Staff were fantastic, room was clean, pet friendly, breakfast was delicious. Had a great stay and I definitely recommend."
The price is ¥16,826
¥18,673 total
includes taxes & fees
Oct 12 - Oct 13
Best Western Plus Parkside Inn & Suites

Drury Plaza Hotel Mt. Vernon

3.0 star property
9.6 out of 10, Exceptional, (1466)
"Loved our stay"
The price is ¥14,031
¥15,866 total
includes taxes & fees
Oct 5 - Oct 6
Drury Plaza Hotel Mt. Vernon

Cobblestone Inn & Suites - Altamont

2.5 star property
9.6 out of 10, Exceptional, (766)
"This hotel is top quality and never disappoints. Very quiet hotel. Fuel and dining options are close by. I have stayed at this location many times and have always been pleased."
Cobblestone Inn & Suites - Altamont

Drury Inn & Suites St. Louis Collinsville

3.0 star property
9.6 out of 10, Exceptional, (1010)
"Had a great stay! Will stay again. "
The price is ¥15,360
¥17,661 total
includes taxes & fees
Oct 19 - Oct 20
Drury Inn & Suites St. Louis Collinsville

Eighteen-Ninety Sleepover

2.5 star property
9.6 out of 10, Exceptional, (305)
"Clean and comfortable "
The price is ¥15,794
¥17,686 total
includes taxes & fees
Sep 28 - Sep 29
Eighteen-Ninety Sleepover

Drury Inn & Suites St. Louis O'Fallon, IL

3.0 star property
9.6 out of 10, Exceptional, (1008)
"Clean, friendly staff, easy check in, comfortable bed, great breakfast, close to airport "
The price is ¥15,065
¥17,473 total
includes taxes & fees
Sep 28 - Sep 29
Drury Inn & Suites St. Louis O'Fallon, IL

Best Western Plus Centralia Hotel & Suites

2.5 star property
9.6 out of 10, Exceptional, (577)
"A good hotel. We always stay there when we travel to centralia to visit family "
The price is ¥20,532
¥22,991 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus Centralia Hotel & Suites

Holiday Inn Express Troy by IHG

2.5 star property
9.4 out of 10, Exceptional, (660)
"The staff was friendly and helpful and the continental breakfast was fantastic."
The price is ¥19,498
¥21,639 total
includes taxes & fees
Oct 12 - Oct 13
Holiday Inn Express Troy by IHG

Drury Inn & Suites Marion

3.0 star property
9.4 out of 10, Exceptional, (1008)
"We had an excellent stay."
The price is ¥13,883
¥16,657 total
includes taxes & fees
Sep 29 - Sep 30
Drury Inn & Suites Marion

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (374)
"Very nice room, nice scenery not an interstate running thru it"
Walker's Bluff Casino Resort

Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

2.5 star property
9.4 out of 10, Exceptional, (480)
"Rooms were clean and comfy, great breakfast "
The price is ¥19,055
¥21,148 total
includes taxes & fees
Oct 8 - Oct 9
Holiday Inn Express & Suites Murphysboro - Carbondale by IHG

La Quinta Inn & Suites by Wyndham Effingham

3.0 star property
9.2 out of 10, Wonderful, (1009)
"Loved the quietness during our stay. "
The price is ¥14,315
¥16,030 total
includes taxes & fees
Oct 2 - Oct 3
La Quinta Inn & Suites by Wyndham Effingham

Best Western Delta Inn

2.5 star property
9.2 out of 10, Wonderful, (1018)
"Courteous staff, feel safe, clean rooms Thank you"
The price is ¥13,182
¥14,761 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Delta Inn

Drury Inn & Suites St. Louis Fairview Heights

3.0 star property
9.2 out of 10, Wonderful, (1020)
"A very comfortable stay!"
The price is ¥13,809
¥15,601 total
includes taxes & fees
Sep 28 - Sep 29
Drury Inn & Suites St. Louis Fairview Heights

Country View Inn & Suites

2.5 star property
9.2 out of 10, Wonderful, (253)
"very nice place with a museum atmosphere "
The price is ¥18,338
¥20,397 total
includes taxes & fees
Sep 24 - Sep 25
Country View Inn & Suites

Cobblestone Hotel & Suites - Newton

2.5 star property
9.2 out of 10, Wonderful, (316)
"Clean, pet friendly, nice breakfast,nice bar area staff was helpful and friendly "
The price is ¥14,039
¥15,580 total
includes taxes & fees
Oct 1 - Oct 2
Cobblestone Hotel & Suites - Newton

Best Western Plus MidAmerica Hotel

2.5 star property
9.0 out of 10, Wonderful, (1006)
"Staff was very helpful..military discount.. Clean rooms and breakfast lounge.."
The price is ¥16,549
¥18,365 total
includes taxes & fees
Sep 28 - Sep 29
Best Western Plus MidAmerica Hotel

TownePlace Suites by Marriott St. Louis O'Fallon

3.0 star property
9.0 out of 10, Wonderful, (125)
"Stayed 4th of July weekend and was very accommodating of our baseball team. "
The price is ¥17,873
¥20,729 total
includes taxes & fees
Oct 19 - Oct 20
TownePlace Suites by Marriott St. Louis O'Fallon

Red Bud Country Inn

2.5 star property
9.0 out of 10, Wonderful, (46)
"Nice staff, very clean, easy parking. "
The price is ¥13,152
¥14,597 total
includes taxes & fees
Oct 19 - Oct 20
Red Bud Country Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southern Illinois, IL

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Stay near popular Southern Illinois attractions

Southern Illinois University
Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

Scott Air Force Base

Scott Air Force Base

After visiting Scott Air Force Base, make a plan to see the other sights and activities in Scott Air Force Base. Attend a sporting event in this family-friendly area.

DuQuoin State Fairgrounds

DuQuoin State Fairgrounds

Catch an event at DuQuoin State Fairgrounds during your trip to Du Quoin. Experience the area's festivals and live music.

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Southern Illinois showing forest scenes, a sunset and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

More cheap stays in Southern Illinois

More cheap stays in Southern Illinois

Hotels in Southern Illinois with star-rating

Hotels in Southern Illinois with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia