Find hotels in Southern Illinois, IL from ¥9,366

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Southern Illinois hotels

Charleston House Bed & Breakfast Inn

Charleston House Bed & Breakfast Inn
4.0 star property
Charleston
10.0 out of 10, Exceptional, (2 reviews)
"Beautifully restored property. Clean and comfortable room, bed, and linens. Wonderful, delicious breakfast prepared and served by the friendly proprietor."
United States
peter
The price is ¥13,470
¥14,949 total
includes taxes & fees
Mar 15 - Mar 16
Charleston House Bed & Breakfast Inn

Holiday Inn Express & Suites Effingham by IHG

Holiday Inn Express & Suites Effingham by IHG
2.5 star property
Effingham
9.4 out of 10, Exceptional, (1,000 reviews)
"Great staff. "
United States
Michael
The price is ¥19,647
¥22,001 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Express & Suites Effingham by IHG

Country Inn & Suites by Radisson, Effingham, IL

Country Inn & Suites by Radisson, Effingham, IL
2.5 star property
Effingham
8.8 out of 10, Excellent, (1,001 reviews)
"Clean room, comfy beds, easy and friendly check in. "
United States
Renee
The price is ¥13,417
¥14,890 total
includes taxes & fees
Mar 29 - Mar 30
Country Inn & Suites by Radisson, Effingham, IL

La Quinta Inn & Suites by Wyndham Effingham

La Quinta Inn & Suites by Wyndham Effingham
3.0 star property
Effingham
9.2 out of 10, Wonderful, (1,002 reviews)
"Good location easy check-in, room was clean and a good breakfast."
United States
James
The price is ¥15,479
¥17,334 total
includes taxes & fees
Mar 22 - Mar 23
La Quinta Inn & Suites by Wyndham Effingham

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon
3.0 star property
Mount Vernon
9.6 out of 10, Exceptional, (1,655 reviews)
"Hotel is very clean, nicely furnished and the beds were so comfy!"
United States
Christina
The price is ¥17,728
¥19,994 total
includes taxes & fees
Apr 3 - Apr 4
Drury Plaza Hotel Mt. Vernon

Quality Inn Effingham North

Quality Inn Effingham North
2.5 star property
Effingham
8.4 out of 10, Very Good, (1,000 reviews)
"It’s a good place to stay for a reasonable price."
United States
Brenda
The price is ¥12,515
¥13,888 total
includes taxes & fees
Mar 29 - Mar 30
Quality Inn Effingham North

Comfort Suites Effingham Central

Comfort Suites Effingham Central
2.5 star property
Effingham
8.8 out of 10, Excellent, (590 reviews)
"Very well maintained, great friendly staff and good breakfast."
United States
James
The price is ¥14,312
¥16,027 total
includes taxes & fees
Mar 22 - Mar 23
Comfort Suites Effingham Central

Ramada by Wyndham Vandalia

Ramada by Wyndham Vandalia
2.0 star property
Vandalia
7.8 out of 10, Good, (820 reviews)
"The room was clean, the staff was friendly, respectful and very helpful "
United States
Dianna
The price is ¥10,862
¥11,838 total
includes taxes & fees
Mar 17 - Mar 18
Ramada by Wyndham Vandalia

Quality Inn & Suites Vandalia near I-70 and Hwy 51

Quality Inn & Suites Vandalia near I-70 and Hwy 51
2.5 star property
Vandalia
8.4 out of 10, Very Good, (1,000 reviews)
"I always stay at this hotel when visiting! Its updated and the staff is so attentive!"
United States
Anessa
The price is ¥10,247
¥11,167 total
includes taxes & fees
Mar 29 - Mar 30
Quality Inn & Suites Vandalia near I-70 and Hwy 51

Super 8 by Wyndham Carbondale

Super 8 by Wyndham Carbondale
2.0 star property
Carbondale
7.4 out of 10, Good, (1,000 reviews)
"Great place "
United States
Christy
The price is ¥10,832
¥12,455 total
includes taxes & fees
Mar 16 - Mar 17
Super 8 by Wyndham Carbondale

Best Western Delta Inn

Best Western Delta Inn
2.5 star property
Effingham
9.2 out of 10, Wonderful, (1,008 reviews)
"Rooms were super clean, and very friendly staff."
United States
Ben
The price is ¥13,545
¥15,167 total
includes taxes & fees
Mar 15 - Mar 16
Best Western Delta Inn

Holiday Inn Express & Suites Vandalia by IHG

Holiday Inn Express & Suites Vandalia by IHG
2.5 star property
Vandalia
8.8 out of 10, Excellent, (797 reviews)
"Easy access good breakfast "
United States
Jeff
The price is ¥19,807
¥21,586 total
includes taxes & fees
Mar 29 - Mar 30
Holiday Inn Express & Suites Vandalia by IHG

Fairfield Inn & Suites Marriott Effingham

Fairfield Inn & Suites Marriott Effingham
3.0 star property
Effingham
9.0 out of 10, Wonderful, (493 reviews)
"Front desk attendant was fantastic."
United States
Richard
The price is ¥15,293
¥16,973 total
includes taxes & fees
Mar 22 - Mar 23
Fairfield Inn & Suites Marriott Effingham

Holiday Inn Effingham by IHG

Holiday Inn Effingham by IHG
3.5 star property
Effingham
9.0 out of 10, Wonderful, (666 reviews)
"Nice place with bar and restaurant on site."
United States
Steve
The price is ¥15,334
¥17,171 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Effingham by IHG

Hampton Inn & Suites Effingham

Hampton Inn & Suites Effingham
2.5 star property
Effingham
9.6 out of 10, Exceptional, (716 reviews)
"Very clean, nice hot breakfast, and kind staff. "
United States
Erin
The price is ¥15,586
¥17,298 total
includes taxes & fees
Mar 22 - Mar 23
Hampton Inn & Suites Effingham

Best Western Heartland Inn

Best Western Heartland Inn
2.5 star property
Mattoon
8.2 out of 10, Very Good, (564 reviews)
"Clean room, kind workers and excellent coffee!"
United States
Kevin
The price is ¥12,871
¥14,413 total
includes taxes & fees
Mar 23 - Mar 24
Best Western Heartland Inn

Drury Inn & Suites Marion

Drury Inn & Suites Marion
3.0 star property
Marion
9.4 out of 10, Exceptional, (1,002 reviews)
"All of the above, enjoyed the evening meal and breakfast, also staff was very friendly. "
United States
Barbara
The price is ¥15,971
¥19,162 total
includes taxes & fees
Apr 6 - Apr 7
Drury Inn & Suites Marion

Ramada by Wyndham Effingham

Ramada by Wyndham Effingham
3.0 star property
Effingham
7.6 out of 10, Good, (1,000 reviews)
"It was a nice place to stay"
United States
Donna
The price is ¥9,097
¥10,187 total
includes taxes & fees
Mar 22 - Mar 23
Ramada by Wyndham Effingham

Eighteen-Ninety Sleepover

Eighteen-Ninety Sleepover
2.5 star property
Casey
9.6 out of 10, Exceptional, (323 reviews)
"Room 210 lovely, clean and historic!"
United States
Danny
The price is ¥16,646
¥18,640 total
includes taxes & fees
Mar 15 - Mar 16
Eighteen-Ninety Sleepover

Cobblestone Inn & Suites - Altamont

Cobblestone Inn & Suites - Altamont
2.5 star property
Altamont
9.6 out of 10, Exceptional, (823 reviews)
"great stay"
United States
Susan
Cobblestone Inn & Suites - Altamont
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Southern Illinois

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southern Illinois attractions

Learn more about Southern Illinois

Discover the culture and history of this region shaped by indigenous and pioneering communities and spend time in its peaceful, picturesque landscapes.

Southern Illinois showing forest scenes, a sunset and landscape views
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southern Illinois Hotel Reviews

More cheap stays in Southern Illinois

Hotels in Southern Illinois with star-rating

Explore a world of travel with Expedia