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Find Resorts & Hotels with Spas in Southern Illinois, IL

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Check availability on Southern Illinois Resorts & Hotels with Spas

Tonight
Oct 10 - Oct 11
Tomorrow
Oct 11 - Oct 12
Next weekend
Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for Southern Illinois hotels with a spa

A modern spa room with a large hot tub, a glass wall with a reflective pattern, and a ceiling with a skylight.
A hotel lobby with a marble floor, a reception desk, a sign for 'Restrooms', and a large chandelier.
A casino interior with slot machines, a large chandelier, and a carpeted floor.
A hotel lobby with a marble floor, a reception area with a '12 & VINE' sign, and a dining area with orange chairs and chandeliers.

1. Walker's Bluff Casino Resort

Walker's Bluff Casino Resort
Carterville
  • Luxurious spa retreat with hot stone massages, sauna, and seasonal pools awaits at this casino resort with attentive staff and fine dining.
￥18,370
￥20,388 total
includes taxes & fees
Oct 13 - Oct 14
Walker's Bluff Casino Resort
A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

2. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
￥15,989
￥18,198 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
A couple relaxing by a window overlooking a bridge and water.
A modern dining area with a long table set for a meal, large windows offering a view of a bridge, and a stone accent wall.
A bar area with a bartender, a bar counter with various bottles, and a view of the Gateway Arch.
A modern hotel lobby with a glass facade, seating area, and a staircase.

3. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
Downtown St. Louis
  • Discover a tranquil haven with 12 treatment rooms, outdoor pool, and breathtaking views at this rejuvenating spa retreat.
￥59,213
￥69,236 total
includes taxes & fees
Oct 15 - Oct 16
Four Seasons Hotel St Louis
A reception desk with a wooden finish and the name "IDOL WOLF" on it.
A multi-story building with a symmetrical facade, large windows, and a central entrance with a canopy.
A modern bathroom with a bathtub, a vanity with a mirror, and a shower area.
A reception area with a curved wooden desk, a laptop, and a chair. The wall has a sign reading "Locust Street Athletic and Swim Club."

4. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
Downtown West
  • Discover spa services, a steam room, and an Olympic-sized indoor pool at this modern hotel, all designed for rejuvenating getaways.
￥22,741
￥27,382 total
includes taxes & fees
Nov 1 - Nov 2
21C Museum Hotel St Louis
A modern kitchen with wooden cabinets, a central island, and framed artwork on the walls.
A bar area with leather seating, a bar counter, and shelves of bottles.
An indoor dining area with a long table, chairs, hanging plants, and a view of a brick building through large windows.
A couple standing on a balcony with a cityscape view.

5. The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis
Clayton
  • Revel in a rejuvenating spa retreat with aromatherapy treatments and hot stone massages at this luxury St. Louis hotel.
￥91,661
￥107,003 total
includes taxes & fees
Nov 1 - Nov 2
The Ritz-Carlton, St. Louis
A modern spa with a curved reception desk, a large mirror, and a decorative water feature.
A bakery display case with various pastries and cakes.
An indoor swimming pool with clear glass walls, metal railings, and a tiled floor.
A bar area with multiple seating arrangements, a stage, and a chandelier.

6. Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
St. Charles
  • Riverside wellness oasis offers full-service spa with aromatherapy and hydrotherapy for a restorative retreat.
￥28,354
￥35,765 total
includes taxes & fees
Oct 12 - Oct 13
Ameristar Casino Resort and Spa
A two-story house with a front porch, a brick foundation, and a gabled roof.
A kitchen with white cabinets, granite countertops, a stainless steel sink, a stove, and a microwave.
A porch with two wicker chairs, a potted plant, and a wooden door.
A traditional interior with a wooden staircase, a desk with a computer, and a red chair.

7. 1895 Washington Hotel

1895 Washington Hotel
Paducah
  • Unwind in a Victorian sanctuary with relaxing reflexology and soothing hydrotherapy treatments for total rejuvenation.
￥9,008
￥12,190 total
includes taxes & fees
Oct 11 - Oct 12
1895 Washington Hotel
A bathroom with a white sink, dark wooden door, and a shower area with striped glass walls.
A modern interior with a staircase, a large abstract painting, and a seating area with a glass coffee table.
A room with a green armchair, a round table, a lamp, and a mirror on the wall.
A room with a bed, a nightstand with a lamp, a painting on the wall, and a radiator.

8. Truitt Hotel

Truitt Hotel
Lafayette Square
￥26,527
￥32,202 total
includes taxes & fees
Oct 18 - Oct 19
Truitt Hotel
A dining area with a wooden table and chairs, a small Christmas tree, and a window with curtains.
A bedroom with a large bed, a nightstand with a lamp, a chair, and a framed picture on the wall.
A dining area with a red wall, a large quilt, and Christmas decorations. There is a window with a view of the outside.
Front of property

9. Arthur's Country Inn

Arthur's Country Inn
Arthur
￥18,681
￥20,733 total
includes taxes & fees
Nov 1 - Nov 2
Arthur's Country Inn
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Choose what matters most at spa hotels in Southern Illinois

Pool
Breakfast included
Hot tub
4 stars
5 stars

Top Southern Illinois Hotel Reviews

Drury Plaza Hotel Mt. Vernon

Drury Plaza Hotel Mt. Vernon

10/10 Excellent
"This was the best hotel I’ve stayed in. The accommodations were outstanding with wonderful people managing the desk! Two young ladies helped us and it was amazing!"
Gina 1-night trip
Posted 19 hours ago
Drury Plaza Hotel Mt. Vernon
Quality Inn O'Fallon - St. Louis - Shiloh

Quality Inn O'Fallon - St. Louis - Shiloh

8/10 Good
"Would stay there again"
Lidia 1-night trip
Posted 20 hours ago
Quality Inn O'Fallon - St. Louis - Shiloh
Drury Inn & Suites St. Louis Fairview Heights

Drury Inn & Suites St. Louis Fairview Heights

10/10 Excellent
"Lovely 3 night stay. Was greeted with a warm welcome, invited for happy hour and a dinner if we did not eat yet! Suite was clean, pool and hot tub area were clean as well. If in area again we will definitely book here!!!"
Jason 3-night trip
Posted 20 hours ago
Drury Inn & Suites St. Louis Fairview Heights
Comfort Suites Mount Vernon

Comfort Suites Mount Vernon

10/10 Excellent
"Of all the hotels I stayed at, these were probably the most comfortable beds I have ever slept in. Rooms for very clean. Pool area was nice. My would maybe suggest a few more options for the breakfast but what they did have was good."
Jennifer 1-night trip
Posted 21 hours ago
Comfort Suites Mount Vernon

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