Find Resorts & Hotels with Spas in South Carolina Midlands, SC

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Nov 7 - Nov 8
Tomorrow
Nov 8 - Nov 9
Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22

Our top choices for South Carolina Midlands hotels with a spa

A spa room with two armchairs, a small table with a vase of flowers, and a sign that reads "SPA Florence".

1. Hotel Florence, Tapestry Collection by Hilton

Hotel Florence, Tapestry Collection by Hilton
3.0 star property
Florence
8.8 out of 10, Excellent, (659 reviews)
  • cleanliness
    Renew your spirit at this historical hotel with an onsite spa offering couples treatments and aromatherapy in the heart of the city.
The price is ￥21,825
￥24,445 total
includes taxes & fees
Nov 20 - Nov 21
Hotel Florence, Tapestry Collection by Hilton
A spa area with a hot tub, stone walls, and large windows offering a view of the outdoors.

2. The Ballantyne, A Luxury Collection Hotel, Charlotte

The Ballantyne, A Luxury Collection Hotel, Charlotte
5.0 star property
Ballantyne
9.4 out of 10, Exceptional, (1,026 reviews)
  • cleanliness
    Escape to a luxurious retreat with 18 treatment rooms, 2 indoor pools, and a sauna at this award-winning spa hotel in Ballantyne.
The price is ￥50,885
￥59,154 total
includes taxes & fees
Dec 6 - Dec 7
The Ballantyne, A Luxury Collection Hotel, Charlotte
A warmly lit lobby with wooden beams, comfortable seating, and potted plants.

3. The Willcox

The Willcox
3.5 star property
Aiken
9.6 out of 10, Exceptional, (158 reviews)
  • cleanliness
    Spa retreat with deep-tissue massages, elegant treatments, and outdoor pool provides a rejuvenating escape.
The price is ￥50,531
￥56,596 total
includes taxes & fees
Nov 15 - Nov 16
The Willcox
A deck with a table and chairs overlooking a lake surrounded by trees.

4. Horizons Sandhills

Horizons Sandhills
4.0 star property
Patrick
The price is ￥39,514
￥43,070 total
includes taxes & fees
Nov 10 - Nov 11
Horizons Sandhills
A luxurious lobby with a grand chandelier, marble flooring, and elegant furniture.

5. Grand Bohemian Charlotte, Autograph Collection

Grand Bohemian Charlotte, Autograph Collection
4.0 star property
Uptown Charlotte
9.4 out of 10, Exceptional, (1,002 reviews)
  • cleanliness
    Rejuvenate at this upscale Charlotte hotel with a full-service spa and rooftop terrace, where urban luxury meets blissful serenity.
The price is ￥39,778
￥46,241 total
includes taxes & fees
Nov 23 - Nov 24
Grand Bohemian Charlotte, Autograph Collection
A hotel room with a bed, a window, and a view of a building and trees.

6. JW Marriott Charlotte

JW Marriott Charlotte
4.5 star property
Uptown Charlotte
9.4 out of 10, Exceptional, (1,005 reviews)
  • cleanliness
    Luxurious spa retreat awaits in downtown Charlotte with indulgent facials, massages, and manicures for a blissful escape into relaxation.
The price is ￥41,420
￥52,726 total
includes taxes & fees
Nov 25 - Nov 26
JW Marriott Charlotte
A cozy living room with a fireplace, a sofa, a leather ottoman, and a chandelier.

7. Morgan and Wells B&B

Morgan and Wells B&B
3.5 star property
Shelby
9.6 out of 10, Exceptional, (102 reviews)
  • cleanliness
    A tranquil bed and breakfast retreat offering couples massages and garden views for a rejuvenating escape.
The price is ￥26,534
￥29,917 total
includes taxes & fees
Nov 11 - Nov 12
Morgan and Wells B&B
A modern living room with a large mirror, white sofas, and round wooden side tables.

8. The Ritz-Carlton, Charlotte

The Ritz-Carlton, Charlotte
5.0 star property
Uptown Charlotte
9.0 out of 10, Wonderful, (321 reviews)
  • cleanliness
    Escape to this luxury spa retreat in downtown Charlotte with body treatments and a serene rooftop garden.
The price is ￥102,211
￥118,821 total
includes taxes & fees
Nov 12 - Nov 13
The Ritz-Carlton, Charlotte
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Choose what matters most at spa hotels in South Carolina Midlands

Pool
Breakfast included

Top South Carolina Midlands Hotel Reviews

A cozy living room with a fireplace, a sofa, a leather ottoman, and a chandelier.
Morgan and Wells B&B

Morgan and Wells B&B

Morgan and Wells B&B
Shelby

10/10 Excellent

I highly recommend Morgan and Wells B&B! Our room was amazing as was the staff and owner. They went out of their way to accommodate us. I look forward to going back there again. You won't want to stay anywhere else in Shelby once you've stayed here.
United States
Anonymous traveler
Reviewed August 9, 2021
Morgan and Wells B&B

Explore a world of travel with Expedia