Find hotels in Santo Domingo, Mexico City from ￥5,378

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Nov 29 - Nov 30
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Dec 12 - Dec 14

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Discover 6,155 Santo Domingo hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Breakfast, lunch, dinner served; Mexican cuisine
Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City

4.0 star property
Historic Center, 12.2 km from Santo Domingo
9.8 out of 10, Exceptional, (2632)
"Great place to stay"
United States
Luke
The price is ￥23,092
￥27,595 total
includes taxes & fees
Dec 7 - Dec 8
Zocalo Central & Rooftop Mexico City
Breakfast, lunch, dinner served; Mexican cuisine
Hotel Catedral

Hotel Catedral

4.0 star property
Historic Center, 12.4 km from Santo Domingo
9.4 out of 10, Exceptional, (2582)
"Room was spotless, breakfast was excellent and hotel staff were welcoming "
United States
Olga
The price is ￥9,205
￥12,428 total
includes taxes & fees
Dec 9 - Dec 10
Hotel Catedral
Lobby
Hotel Bellas Artes

Hotel Bellas Artes

4.0 star property
Historic Center, 12.1 km from Santo Domingo
9.8 out of 10, Exceptional, (514)
"Loved this hotel from the location to how nice, modern and clean it was plus staff was amazing. Definitely booking here again!"
United States
Danika
The price is ￥12,115
￥14,800 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Bellas Artes
2 bars/lounges
Hotel Parque Satelite

Hotel Parque Satelite

3.0 star property
22.4 km from Santo Domingo
9.2 out of 10, Wonderful, (1021)
"Good place to stay nice and clean"
United States
guillermo
The price is ￥7,619
￥9,143 total
includes taxes & fees
Dec 1 - Dec 2
Hotel Parque Satelite
Indoor pool, outdoor pool
Hilton Mexico City Reforma

Hilton Mexico City Reforma

4.5 star property
Reforma, 12 km from Santo Domingo
9.4 out of 10, Exceptional, (1057)
"great place . friendly staff and everything was to perfection."
United States
Adriana
The price is ￥29,327
￥35,045 total
includes taxes & fees
Dec 7 - Dec 8
Hilton Mexico City Reforma
Interior
Hotel Juarez

Hotel Juarez

2.5 star property
Historic Center, 12.2 km from Santo Domingo
9.0 out of 10, Wonderful, (1780)
"Very good tourist place. "
United States
Guillermina
The price is ￥4,500
￥5,378 total
includes taxes & fees
Dec 4 - Dec 5
Hotel Juarez
Standard Room, 2 Double Beds, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace
Sleep Inn Ciudad de México

Sleep Inn Ciudad de México

3.0 star property
12.3 km from Santo Domingo
8.4 out of 10, Very Good, (999)
"Nice hotel. "
United States
Alejandra
The price is ￥10,775
￥12,876 total
includes taxes & fees
Dec 7 - Dec 8
Sleep Inn Ciudad de México
Standard Double Room, 2 Double Beds | Desk, soundproofing, free WiFi
ibis Mexico Tlalnepantla

ibis Mexico Tlalnepantla

3.0 star property
23.6 km from Santo Domingo
8.6 out of 10, Excellent, (1017)
"Room was clean and staff were friendly and helpful"
Ireland
Gary
The price is ￥6,089
￥7,307 total
includes taxes & fees
Dec 21 - Dec 22
ibis Mexico Tlalnepantla
Reception
Royal Pedregal Hotel

Royal Pedregal Hotel

4.0 star property
Tlalpan, 4.6 km from Santo Domingo
9.0 out of 10, Wonderful, (1806)
"Excellent option if you need to be in the southern part of CDMX"
United States
Carlos
Royal Pedregal Hotel
Front of property
Historico Central Hotel

Historico Central Hotel

4.0 star property
Historic Center, 12 km from Santo Domingo
9.8 out of 10, Exceptional, (2408)
"Location was great and hotel was clean and comfortable "
United States
Daniela
The price is ￥18,014
￥21,527 total
includes taxes & fees
Dec 18 - Dec 19
Historico Central Hotel
View from room
Hotel Punto MX

Hotel Punto MX

3.5 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1418)
"Everything was perfect! Room , location, "
United States
Yohena
The price is ￥8,782
￥10,547 total
includes taxes & fees
Dec 8 - Dec 9
Hotel Punto MX
Front of property
Camino Real Santa Fe

Camino Real Santa Fe

5.0 star property
Santa Fe, 11 km from Santo Domingo
9.0 out of 10, Wonderful, (2707)
"Great place to stay "
United States
KARLA
The price is ￥11,128
￥13,297 total
includes taxes & fees
Dec 20 - Dec 21
Camino Real Santa Fe
Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, blackout drapes
Holiday Inn Express Mexico Basilica by IHG

Holiday Inn Express Mexico Basilica by IHG

3.0 star property
14.7 km from Santo Domingo
9.2 out of 10, Wonderful, (1036)
"Excellent stay!"
United States
Derek
The price is ￥10,237
￥12,233 total
includes taxes & fees
Dec 22 - Dec 23
Holiday Inn Express Mexico Basilica by IHG
Exterior
Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico

3.0 star property
Historic Center, 11.7 km from Santo Domingo
9.0 out of 10, Wonderful, (1070)
"Felt safe and was walking distance to stores and food "
United States
MARIA
The price is ￥13,619
￥16,275 total
includes taxes & fees
Dec 8 - Dec 9
Hampton Inn & Suites Mexico City - Centro Historico
Deluxe Double Room | In-room safe, blackout drapes, soundproofing, iron/ironing board
Punta Alameda

Punta Alameda

2.0 star property
Downtown Mexico City, 11.6 km from Santo Domingo
9.4 out of 10, Exceptional, (182)
"Regular cleaning, friendly staff"
Canada
Mukul
Punta Alameda
Lobby
Fiesta Americana México Toreo

Fiesta Americana México Toreo

4.0 star property
15 km from Santo Domingo
9.6 out of 10, Exceptional, (1018)
"It was a wonderful stay"
United States
Lukas
The price is ￥24,814
￥29,777 total
includes taxes & fees
Dec 22 - Dec 23
Fiesta Americana México Toreo
Terrace/patio
Hotel Brasilia

Hotel Brasilia

3.0 star property
16.5 km from Santo Domingo
9.0 out of 10, Wonderful, (1011)
"Super clean hotel and the staff very pleasant and friendly."
United States
Emanuel
The price is ￥9,287
￥11,098 total
includes taxes & fees
Dec 7 - Dec 8
Hotel Brasilia
Sundeck
Galeria Plaza San Jeronimo

Galeria Plaza San Jeronimo

4.0 star property
5.1 km from Santo Domingo
9.2 out of 10, Wonderful, (1016)
"Enjoyed the stay "
United States
Simon
The price is ￥15,985
￥19,102 total
includes taxes & fees
Dec 14 - Dec 15
Galeria Plaza San Jeronimo
Exterior
Hotel Plaza Revolución

Hotel Plaza Revolución

3.5 star property
12.1 km from Santo Domingo
8.8 out of 10, Excellent, (1011)
"Good location close to everything was a positive experience "
United States
Andres
Hotel Plaza Revolución
Terrace/patio
Fiesta Inn Insurgentes Sur

Fiesta Inn Insurgentes Sur

3.5 star property
4.4 km from Santo Domingo
9.2 out of 10, Wonderful, (1025)
"Excellent hotel. "
United States
Annie
The price is ￥17,055
￥20,710 total
includes taxes & fees
Dec 6 - Dec 7
Fiesta Inn Insurgentes Sur
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santo Domingo

Find the best Santo Domingo areas and neighborhoods for the activities you enjoy most.
Polanco featuring a church or cathedral, a park and heritage architecture

Polanco

Luxury shopping along Presidente Masaryk Avenue and upscale restaurants await, while nearby Chapultepec Park houses the National Museum of Anthropology and other cultural institutions. Enjoy a stroll in Parque Lincoln or explore Polanquito's vibrant dining scene.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like Avenida Insurgentes and MUCA Roma, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

La Condesa featuring cafe lifestyle

La Condesa

Fashionable and popular with young professionals, Condesa boasts international restaurants, bars, and nightclubs. Stroll along tree-lined avenues, admire Art Deco architecture, and visit landmarks like Edificio San Martín and Basurto Building.

Metropolitan Cathedral showing street scenes, heritage elements and a church or cathedral

Historic Center

Historic center with 1,550 significant buildings, the neighborhood offers museums like MUNAL and Palacio de Bellas Artes. Enjoy upscale eateries, fashionable stores, and pedestrianized streets for easy exploration.

Reforma featuring city views, a city and night scenes

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Domingo Hotel Reviews

ULIV Mexico City

ULIV Mexico City

10/10 Excellent
"Great location close to everything. Views are spectacular & the cleanliness was great. "
Aime 2-night trip
Posted 7 hours ago
ULIV Mexico City

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Frequently asked questions

What is Santo Domingo like?
Travelers to Mexico City's Santo Domingo neighborhood will be sure to enjoy a stay in this neighborhood.
How many hotels should I expect to find in the Santo Domingo area?
Book one of Expedia's 5 hotels and other accommodations in Santo Domingo and start exploring everything Mexico City has to offer.
If I need to cancel my hotel reservation in Santo Domingo, will I receive a refund?
Yes, most room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to get the best deals in Santo Domingo.
Where can I learn more about changing or cancelling my trip to Santo Domingo?
For additional details about updating your trip to Santo Domingo or cancelling it, click here.
What are the top things to see and do in Santo Domingo?
Parroquia de San Juan Bautista, Casa del Teatro, and Museo Diego Rivera Anahuacalli are just a few of the places to visit in and around Santo Domingo. While you're out sightseeing, Museo de la Ciudad and Hidalgo Plaza are a couple of additional sights to visit in Mexico City.