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Compare 1,696 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Apartment, 3 Bedrooms, Accessible, Pool View | Children's area
Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City

2.0 star property
José Domingo Espinar
The price is ￥11,055
￥12,160 total
includes taxes & fees
Dec 7 - Dec 8
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Outdoor pool, pool umbrellas, sun loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4.0 star property
Tocumen
8.4 out of 10, Very Good, (2293)
"The room was clean and the staff were nice! "
United States
CECILIA
The price is ￥17,086
￥18,795 total
includes taxes & fees
Dec 23 - Dec 24
Crowne Plaza Panama Airport by IHG
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

4.0 star property
Casco Viejo
9.0 out of 10, Wonderful, (1002)
"Great staff, perfect location, and delicious breakfast. "
United States
Tatiana
The price is ￥36,337
￥39,971 total
includes taxes & fees
Dec 8 - Dec 9
Central Hotel Panama Casco Viejo
Living area
ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

2.0 star property
Tocumen
9.0 out of 10, Wonderful, (32)
"Very nice boutique hotel"
United States
Fernando
The price is ￥18,616
￥20,478 total
includes taxes & fees
Dec 12 - Dec 13
ORHO HOTEL BOUTIQUE PANAMA Airport
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

4.0 star property
Casco Viejo
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is ￥34,917
￥38,409 total
includes taxes & fees
Dec 15 - Dec 16
La Concordia Boutique Hotel
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1000)
"I loved everything about my stay "
United States
Stephanie
The price is ￥27,858
￥30,644 total
includes taxes & fees
Dec 15 - Dec 16
Waldorf Astoria Panama
3 outdoor pools, pool umbrellas, sun loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

5.0 star property
Veracruz
8.0 out of 10, Very Good, (1002)
"Clean rooms , friendly staff , had great experience "
United States
Saro
The price is ￥25,801
￥28,381 total
includes taxes & fees
Dec 16 - Dec 17
The Westin Playa Bonita Panama
Outdoor pool
Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina

3.0 star property
Bella Vista
7.4 out of 10, Good, (267)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is ￥13,186
￥14,505 total
includes taxes & fees
Jan 6 - Jan 7, 2026
Ramada Panama Centro Via Argentina
Reception
Hotel Coral Suites

Hotel Coral Suites

3.5 star property
Bella Vista
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is ￥10,345
￥11,379 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Coral Suites
Aerial view
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

3.5 star property
Colon
7.8 out of 10, Good, (661)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is ￥16,690
￥18,631 total
includes taxes & fees
Dec 14 - Dec 15
Gamboa Rainforest Reserve
Exterior
Aloft Panama

Aloft Panama

3.5 star property
San Francisco
8.8 out of 10, Excellent, (889)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is ￥18,150
￥19,965 total
includes taxes & fees
Dec 15 - Dec 16
Aloft Panama
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

3.5 star property
Bella Vista
9.2 out of 10, Wonderful, (1005)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is ￥11,945
￥13,140 total
includes taxes & fees
Dec 8 - Dec 9
TRYP by Wyndham Panamá Centro
Outdoor pool, open 7:00 AM to 10:30 PM, free cabanas, pool umbrellas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

4.0 star property
Tocumen
8.6 out of 10, Excellent, (1857)
"I love the included shuttle and breakfast and how close it is to the airport"
United States
leon
The price is ￥19,399
￥21,339 total
includes taxes & fees
Dec 12 - Dec 13
Riande Aeropuerto Hotel & Casino
Front of property - evening/night
Principe Hotel and Suites

Principe Hotel and Suites

3.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1581)
"Great hotel, location, food. Highly recommend the sushi restaurant next door.. One of the best ever. "
United States
Lakshmin
The price is ￥7,766
￥8,543 total
includes taxes & fees
Dec 20 - Dec 21
Principe Hotel and Suites
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

4.5 star property
Casco Viejo
9.8 out of 10, Exceptional, (257)
"Great location!"
United States
Erik
The price is ￥50,039
￥55,043 total
includes taxes & fees
Dec 23 - Dec 24
Hotel La Compañía Casco Antiguo
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4.0 star property
Cerro Viento
8.8 out of 10, Excellent, (1002)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is ￥16,372
￥18,009 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Courtyard by Marriott Panama Metromall
Front of property
Hotel San Felipe

Hotel San Felipe

4.0 star property
Casco Viejo
9.4 out of 10, Exceptional, (243)
"Really nice staff and property is in amazing location "
United States
Michael
The price is ￥16,289
￥17,918 total
includes taxes & fees
Dec 16 - Dec 17
Hotel San Felipe
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 star property
Bella Vista
7.6 out of 10, Good, (689)
"The breakfast was great, I love the pool."
United States
Estefani
The price is ￥8,600
￥9,460 total
includes taxes & fees
Dec 8 - Dec 9
Hospedium Princess Hotel Panama
Couples treatment rooms, sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1000)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is ￥28,994
￥31,893 total
includes taxes & fees
Dec 7 - Dec 8
Bristol Panama, a Registry Collection Hotel
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (635)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is ￥35,951
￥39,546 total
includes taxes & fees
Dec 12 - Dec 13
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa Pera Hotel Reviews

Sheraton Grand Panama

Sheraton Grand Panama

10/10 Excellent
"Was amazing food was delicious and stay was great "
Amanda 5-night trip
Posted 2 days ago
Sheraton Grand Panama

More cheap stays in Santa Pera

Arcadia Condo Suites

Arcadia Condo Suites

Calle rio mar Panama City Panamá Province
The price is ￥9,773 per night from Dec 15 to Dec 16
￥9,773
￥17,917 total
Dec 15 - Dec 16
includes taxes & fees
9.4/10 Exceptional! (150 reviews)

Frequently asked questions

What's the best place to stay in Santa Pera?
Located 6 mi (9.7 km) from the heart of Santa Pera, Hotel Riu Plaza Panama is a top choice for your stay based on our traveler data. Other good options for your trip to the area are Crowne Plaza Panama Airport by IHG and Las Americas Golden Tower Panama. See all available top hotels, or vacation rentals in Santa Pera.
What's the top vacation rental that Santa Pera has to offer?
Panama View House – A Hilltop Retreat with Stunning Canal Views: Visitors like this Santa Pera vacation home rental. It has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. See all vacation rentals in Santa Pera.
If I need to cancel my hotel reservation in Santa Pera, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Pera.
Where can I learn more about changing or cancelling my trip to Santa Pera?
To access more information about rescheduling or cancelling your trip to Santa Pera, go to https://www.expedia.com/service/.
What are some hotels with pools in Santa Pera?
Hotel Riu Plaza Panama: Hotel, 9-minute walk from Avenida Balboa. Features 3 restaurants, an outdoor pool, and buffet. Crowne Plaza Panama Airport by IHG and Megapolis Hotel Panamá are a couple of other choices that offer an onsite pool. View all hotels with pools in Santa Pera.
How is it to stay in Santa Pera?
Travelers to Santa Pera will find plenty to explore and enjoy. A top sight in the area is Albrook Shopping Mall. In Santa Pera, there are 3 hotels and other accommodations to choose from. Find out more about Santa Pera.
What is there to see in Santa Pera?
Albrook Shopping Mall is a notable place to visit in the area. You'll also find Metromall Panama and Estadio Rommel Fernandez in the area. Check out what more to see and do in Expedia's Santa Pera guide.
What's the seasonal weather like in Santa Pera?
The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Santa Pera are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.

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