Find hotels near Mayo Clinic, Rochester from ￥12,116

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Jan 14 - Jan 15
Tomorrow
Jan 15 - Jan 16
This weekend
Jan 16 - Jan 18
Next weekend
Jan 23 - Jan 25

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mayo Clinic hotels

Presidential Suite, Multiple Beds | Living area | LCD TV
Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.6 out of 10, Exceptional, (552 reviews)
"Very courteous staff, loved the valet guy!"
United States
Jean
The price is ￥27,083
￥31,180 total
includes taxes & fees
Jan 24 - Jan 25
Hilton Rochester Mayo Clinic Area
Pub
TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park, 0.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (486 reviews)
"Room was large, clean, beds were comfortable. Downstairs cafe and seating areas were very comfortable."
United States
Ann
The price is ￥20,070
￥23,105 total
includes taxes & fees
Feb 6 - Feb 7
TownePlace Suites by Marriott Rochester Mayo Clinic Area
View from property
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
2.5 star property
Kutzky Park, 1.8 km from Mayo Clinic
9.6 out of 10, Exceptional, (684 reviews)
"Good place to stay when traveling to Mayo apots"
United States
Carolyn
The price is ￥15,602
￥17,963 total
includes taxes & fees
Jan 30 - Jan 31
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
Lobby
The Berkman

The Berkman

The Berkman
3.0 star property
Folwell, 1.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (378 reviews)
"The room was amazing, spacious, nicely decorated, super clean, complete kitchen, bedroom separated from living… High quality finishes. Very good location accross the street from Mayo. "
United States
Juliana
The Berkman
Courtyard
EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (979 reviews)
"The staff was very friendly and the room spotless. "
United States
Judith
The price is ￥18,806
￥21,967 total
includes taxes & fees
Feb 6 - Feb 7
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Terrace/patio
Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
2.6 km from Mayo Clinic
9.6 out of 10, Exceptional, (899 reviews)
"Great stay,clean and friendly"
United States
Janet
The price is ￥19,308
￥22,228 total
includes taxes & fees
Jan 22 - Jan 23
Home2 Suites by Hilton Rochester Mayo Clinic Area
Indoor pool
Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South

Residence Inn by Marriott Rochester Mayo Clinic Area South
3.0 star property
2.4 km from Mayo Clinic
9.6 out of 10, Exceptional, (260 reviews)
"Staff was great and helpful, lovely room!, quiet area, restaurants nearby"
United States
Ann Marie
The price is ￥22,440
￥25,833 total
includes taxes & fees
Jan 18 - Jan 19
Residence Inn by Marriott Rochester Mayo Clinic Area South
Lobby
Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park, 1 km from Mayo Clinic
9.4 out of 10, Exceptional, (431 reviews)
"Great room, location, very clean "
United States
John
The price is ￥22,925
￥26,711 total
includes taxes & fees
Jan 18 - Jan 19
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Two-Bedroom Apartment - Mobility Accessible/Non-Smoking | In-room safe, individually furnished, desk, laptop workspace
Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
9.2 out of 10, Wonderful, (168 reviews)
"Great staff, clean room, spacious kitchen and living room."
United States
silvia
The price is ￥24,893
￥28,660 total
includes taxes & fees
Jan 24 - Jan 25
Broadway Plaza, Trademark Collection by Wyndham
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester, 0.5 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,004 reviews)
"Great place to stay"
United States
Cristopher
The price is ￥21,174
￥24,376 total
includes taxes & fees
Jan 31 - Feb 1
Hyatt House Rochester/Mayo Clinic Area
Exterior
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (776 reviews)
"Staff was very helpful and positive. "
United States
Bradley
The price is ￥14,855
￥17,102 total
includes taxes & fees
Feb 6 - Feb 7
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Terrace/patio
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
3.0 star property
Kutzky Park, 1.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (487 reviews)
"Being so close to St Mary's sure helped with our hospital stay. "
United States
Kevin
The price is ￥18,407
￥21,192 total
includes taxes & fees
Feb 14 - Feb 15
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Lobby sitting area
Brentwood Inn & Suites

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (1,001 reviews)
"Clean and comfortable Close to the hospital for convenience "
United States
Dianne
Brentwood Inn & Suites
Exterior
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester, 0.4 km from Mayo Clinic
8.8 out of 10, Excellent, (911 reviews)
"Great stay as always! "
United States
Misty
The price is ￥12,099
￥13,930 total
includes taxes & fees
Jan 30 - Jan 31
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Breakfast served
Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN

Hilton Garden Inn Rochester Downtown, MN
3.0 star property
Downtown Rochester, 0.3 km from Mayo Clinic
8.8 out of 10, Excellent, (861 reviews)
"Transportation services very good staff very helpful."
United States
Joyce
The price is ￥16,914
￥19,473 total
includes taxes & fees
Feb 6 - Feb 7
Hilton Garden Inn Rochester Downtown, MN
Front of property
Aspen Suites

Aspen Suites

Aspen Suites
3.0 star property
1.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (706 reviews)
"The staff was very friendly, room was very clean "
United States
Ci Ci
Aspen Suites
Exterior
Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG

Candlewood Suites Rochester Mayo Clinic Area by IHG
2.5 star property
2.6 km from Mayo Clinic
9.2 out of 10, Wonderful, (456 reviews)
"The staff checking in and out were helpful and friendly. The room was clean, comfortable, and quiet. "
United States
Allison
The price is ￥13,907
￥16,010 total
includes taxes & fees
Feb 4 - Feb 5
Candlewood Suites Rochester Mayo Clinic Area by IHG
Reception
Hampton Inn Rochester-South

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
2.9 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,001 reviews)
"Great place"
United States
Randall
The price is ￥12,521
￥14,414 total
includes taxes & fees
Feb 3 - Feb 4
Hampton Inn Rochester-South
Free daily full breakfast
Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area

Econo Lodge Mayo Clinic Area
2.0 star property
3.1 km from Mayo Clinic
9.0 out of 10, Wonderful, (917 reviews)
"Staff were awesome. "
United States
Damon
The price is ￥10,525
￥12,116 total
includes taxes & fees
Jan 24 - Jan 25
Econo Lodge Mayo Clinic Area
Exterior
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG

Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
2.5 star property
Kutzky Park, 1.6 km from Mayo Clinic
8.8 out of 10, Excellent, (771 reviews)
"the staff was friendly and helpful/ and the room was clean/ and good amenities"
United States
carol
The price is ￥16,277
￥18,739 total
includes taxes & fees
Jan 18 - Jan 19
Holiday Inn Express & Suites Rochester – Mayo Clinic Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mayo Clinic Hotel Reviews

Aspen Suites

Aspen Suites

10/10 Excellent
"The staff was very friendly, room was very clean "
Ci Ci 5-night trip
Posted 4 days ago
Aspen Suites

Hotels near other Mayo Clinic attractions

Soldiers Field Veterans Memorial

4.5/5 (30 reviews)
You can learn about the history of Rochester with a visit to Soldiers Field Veterans Memorial. Attend a sporting event or simply visit the area's shops.
See properties

Plummer Building

You can find out about the history of Rochester when you stop by Plummer Building.
See properties

Frequently asked questions

What's the area like around Mayo Clinic?
Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 158 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic?
Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hotel Indigo Rochester – Mayo Clinic Area by IHG.
How many hotels will I be able to find near Mayo Clinic?
Expedia has 158 hotels and other accommodations within a mile from Mayo Clinic.
If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?
Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?
For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.
What can I see and do near Mayo Clinic?
You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Assisi Heights and Plummer House. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.

Explore a world of travel with Expedia