Top Destination Hotels in James Island, SC from ￥39,668

A lighthouse on a pier extending into a calm body of water.

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Our top choices for James Island Destination Hotels

A resort with multiple swimming pools, lounge areas, and a fire pit.

A golf course with bunkers, a sand trap, and a building in the background.

A coastal town with beachfront properties and a marina.

A resort with multiple buildings, two swimming pools, and a beach area with sun loungers.

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Isle of Palms

Michelle

￥29,451

￥39,668 total

includes taxes & fees

Nov 4 - Nov 5

A beachfront hotel with a pool, beach access, and a sunset view.

A spacious living area with a sofa, coffee table, and dining table. A kitchen with granite countertops and wooden cabinets is visible.

A coastal hotel with multiple buildings, a beach in the background, and surrounding greenery.

2. Wild Dunes Resort – Residences at Sweetgrass

Isle of Palms

Jeff

￥36,260

￥48,670 total

includes taxes & fees

Nov 4 - Nov 5

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Top James Island Hotel Reviews

The Francis Marion Hotel

10/10 Excellent

"Beautiful old hotel. Toilets could use a little TLC, they don’t flush very well. Tried two rooms. Would definitely recommend."

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent

"Restaurant was conveniently located and had great breakfast food."

Cambria Hotel Mount Pleasant – Charleston

10/10 Excellent

"Great location and price for a weekend in Charleston. We were able to get downtown with no issues. Plus there are so many great restaurants in Mount Pleasant. Room was clean and bed was very comfortable."

The Palmetto Hotel

10/10 Excellent

"Location was fabulous. Best bartenders in town."

La Quinta Inn & Suites by Wyndham Charleston Riverview

10/10 Excellent

"I would like to see USB access to charge devices like my iPhone"

Drury Plaza Hotel North Charleston

10/10 Excellent

"Everyone was very friendly. Breakfast and dinners were wonderful. Only thing I could ask for is lotion in the room and more firm pillows."

Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG

10/10 Excellent

"Great location, very close to downtown Charleston. The rooms are comfortable, and the breakfast is excellent, with a great variety of options. Overall, a very nice place to stay!"