Top Destination Hotels in James Island, SC from ￥35,977

A rustic wooden interior with a table, a basket, and a painting on easels.

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Our top choices for James Island Destination Hotels

1. Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Isle of Palms

vanessa

￥26,661

￥35,977 total

includes taxes & fees

Sep 7 - Sep 8

Desk, iron/ironing board, WiFi (free), bed sheets

2. Wild Dunes Resort – Residences at Sweetgrass

Isle of Palms

Thomas

￥31,394

￥42,232 total

includes taxes & fees

Sep 7 - Sep 8

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Top James Island Hotel Reviews

The Francis Marion Hotel

10/10 Excellent

"Clean, nice staff, and convenient restaurant downstairs."

The Beach Club at Charleston Harbor Resort and Marina

10/10 Excellent

"We’ll love the Beach Club at Charleston Harbor resort. We have coming here for 6 yrs and it is our favorite place to vacation. We love taking the water taxi over to Charleston from the resort."

The Charleston Place

10/10 Excellent

"One of the best hotels we have ever stayed in. Staff is amazing."

Cambria Hotel Mount Pleasant – Charleston

10/10 Excellent

"Staff was very friendly and helpful. Room was very clean."

Holiday Inn Express Charleston by IHG

8/10 Good

"A light pole has fallen in the parking lot and has been there for at least 3 months. It was there at my previous stay and still there last week, Hot breakfast was not available due to an issue with the oven. We still had a continental breakfast but not quite the same. The room darkening shade was not functional in the room or bathroom. I wasn't sure how much was visible from the outside looking in. Nothing was really bad, just not up to my usual expectations of this property."

Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG

10/10 Excellent

"The rooms were clean and very comfortable. The complimentary breakfast was delicious. Parking is a little tricky but manageable."

The Vendue

10/10 Excellent

"My wife and I spent a wonderful week at the Vendue. The hotel is located in the French Quarter surrounded by plenty of restaurants and historical activities. The staff was exceptionally friendly and accommodating. We will definitely return."