Find hotels in Commerce, MO from ￥9,876

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Dec 8 - Dec 9
Tomorrow
Dec 9 - Dec 10
This weekend
Dec 12 - Dec 14
Next weekend
Dec 19 - Dec 21

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Compare 80 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (661)
"Great place "
United States
GUY
The price is ￥12,147
￥13,146 total
includes taxes & fees
Jan 5 - Jan 6, 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Clean room, great location and friendly staff"
United States
Mark
The price is ￥13,978
￥16,070 total
includes taxes & fees
Dec 13 - Dec 14
Drury Inn & Suites Sikeston, MO
Front of property - evening/night
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2.0 star property
Charleston
6.6 out of 10, (612)
"Staff was great! Room was nice. "
United States
Lana
The price is ￥9,786
￥10,859 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1004)
"Great stay"
United States
Heather
The price is ￥10,872
￥12,265 total
includes taxes & fees
Dec 14 - Dec 15
Pear Tree Inn Cape Girardeau West
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1005)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ￥10,872
￥12,265 total
includes taxes & fees
Dec 14 - Dec 15
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is ￥14,756
￥16,648 total
includes taxes & fees
Dec 22 - Dec 23
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Business center
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"I do love this hotel chain. Another great visit!"
United States
Mark
The price is ￥13,978
￥15,767 total
includes taxes & fees
Dec 14 - Dec 15
Drury Inn & Suites Cape Girardeau
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is ￥13,978
￥15,767 total
includes taxes & fees
Dec 14 - Dec 15
Drury Plaza Hotel Cape Girardeau Conference Center
Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (782)
"Excellent stay"
United States
Christina
The price is ￥15,409
￥17,383 total
includes taxes & fees
Dec 22 - Dec 23
Hampton Inn Cape Girardeau I 55 East
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is ￥18,018
￥20,416 total
includes taxes & fees
Dec 22 - Dec 23
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Quality Inn

Quality Inn

2.5 star property
Cape Girardeau
7.2 out of 10, Good, (680)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is ￥8,974
￥10,124 total
includes taxes & fees
Dec 16 - Dec 17
Quality Inn
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is ￥13,669
￥15,421 total
includes taxes & fees
Dec 18 - Dec 19
Fairfield Inn & Suites by Marriott Cape Girardeau
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (99)
"It was a nice stay"
United States
Douglas
The price is ￥13,545
￥15,415 total
includes taxes & fees
Dec 15 - Dec 16
Tru By Hilton Cape Girardeau
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
Jackson
8.2 out of 10, Very Good, (739)
"Dirty "
United States
Jon
The price is ￥12,395
￥13,415 total
includes taxes & fees
Dec 28 - Dec 29
Comfort Suites Jackson-Cape Girardeau
Desk, laptop workspace, blackout drapes, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is ￥10,129
￥11,240 total
includes taxes & fees
Dec 27 - Dec 28
Quality Inn Charleston - Sikeston
Standard Room, 1 Queen Bed, Non Smoking, Garden View | Free WiFi
Rockwood Inn

Rockwood Inn

2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is ￥21,942
￥24,754 total
includes taxes & fees
Dec 11 - Dec 12
Rockwood Inn
Lobby sitting area
The Riverview

The Riverview

4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (466)
"Place was nice and safe"
United States
ryan
The price is ￥13,762
￥15,526 total
includes taxes & fees
Dec 17 - Dec 18
The Riverview
Lobby
Quality Inn Cairo I-57

Quality Inn Cairo I-57

2.5 star property
Cairo
6.6 out of 10, (273)
"Break fast was excellent "
United States
Uma
The price is ￥11,114
￥12,334 total
includes taxes & fees
Dec 27 - Dec 28
Quality Inn Cairo I-57
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.2 out of 10, Very Good, (878)
"Clean room, low noise and very comfortable!"
United States
Richard
The price is ￥10,873
￥13,120 total
includes taxes & fees
Dec 14 - Dec 15
Candlewood Suites Cape Girardeau by IHG
Iron/ironing board, free WiFi, bed sheets
Country Yard Inn and Suite

Country Yard Inn and Suite

2.0 star property
Sikeston
6.8 out of 10, (118)
"Great spot en route home from Mississippi. Staff put me in a room that ended up being in a quiet section of the hotel. Great sleep."
United States
Andrew
The price is ￥8,301
￥9,876 total
includes taxes & fees
Dec 10 - Dec 11
Country Yard Inn and Suite
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Commerce Hotel Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

10/10 Excellent
"Very nice staff and very clean"
Jacquelyn 1-night trip
Posted 5 days ago
Pear Tree Inn Cape Girardeau Near the Medical Center

More cheap stays in Commerce

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO
The price is ￥10,872 per night from Dec 14 to Dec 15
￥10,872
￥12,265 total
Dec 14 - Dec 15
includes taxes & fees
9/10 Wonderful! (1,000 reviews)

Frequently asked questions

What's the best place to stay in Commerce?
Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay based on our traveler data. Two other options for your trip to the area are The Riverview and Pear Tree Inn Cape Girardeau West. See all available top hotels, or vacation rentals in Commerce.
What are some of the best vacation home rentals in Commerce?
Little Blue Cottage on Spanish: This vacation home near Commerce comes with WiFi so you can feel at home during your trip. See all vacation rentals in Commerce.
If I need to cancel my hotel reservation in Commerce, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.
Where can I learn more about changing or cancelling my trip to Commerce?
To find more details about rescheduling or cancelling your trip to Commerce, go to https://www.expedia.com/service/.
What's it like to stay in Commerce?
Travelers to Commerce will find plenty to explore and enjoy. There are 79 hotels and other accommodations in the surrounding area. Find out more about Commerce.
What is there to see in Commerce?
A favorite place to visit is Mississippi River. You'll also find Isle Casino Cape Girardeau and Show Me Center in the area. Check out what more to see and do in Expedia's Commerce guide.
What's the weather like in Commerce?
The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 40°F. Average annual precipitation for Commerce is 59 inches.

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