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Compare 1,412 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Waymore Hotel Spa & Casino

4.0 star property
9.0 out of 10, Wonderful, (346)
"Great hotel for the price."
The price is ¥11,880
¥13,068 total
includes taxes & fees
Jul 20 - Jul 21
Waymore Hotel Spa & Casino

Crowne Plaza Panama Airport by IHG

4.0 star property
8.4 out of 10, Very Good, (2150)
"Great spot for the night, close to the airport "
The price is ¥18,392
¥20,231 total
includes taxes & fees
Aug 3 - Aug 4
Crowne Plaza Panama Airport by IHG

Principe Hotel and Suites

3.0 star property
9.0 out of 10, Wonderful, (1402)
"Good place to stay. "
The price is ¥8,677
¥9,545 total
includes taxes & fees
Jul 26 - Jul 27
Principe Hotel and Suites

Hyatt Regency Panama City

4.5 star property
10.0 out of 10, Exceptional, (36)
"Friendly staff.. great food and in a convenient location to allow pick up for tours"
The price is ¥22,567
¥24,824 total
includes taxes & fees
Jul 25 - Jul 26
Hyatt Regency Panama City

Hotel Milan

3.0 star property
9.0 out of 10, Wonderful, (372)
"I enjoyed my stay "
The price is ¥5,933
¥6,526 total
includes taxes & fees
Jul 20 - Jul 21
Hotel Milan

Marriott Panama Hotel

4.0 star property
9.0 out of 10, Wonderful, (1002)
"Excellent location, staff were pleasant and professional "
The price is ¥19,978
¥21,977 total
includes taxes & fees
Aug 15 - Aug 16
Marriott Panama Hotel

The Executive Hotel

3.5 star property
9.2 out of 10, Wonderful, (1008)
"Staff great, gym great, hotel convenient and pleasant."
The Executive Hotel

Arcadia Condo Suites

2.5 star property
9.4 out of 10, Exceptional, (35)
"The view, The location, the convenience. "
Arcadia Condo Suites

Las Americas Golden Tower Panama

4.0 star property
8.8 out of 10, Excellent, (1001)
"Spacious, clean , friendly and helpful staff "
The price is ¥17,211
¥18,932 total
includes taxes & fees
Jul 31 - Aug 1
Las Americas Golden Tower Panama

Studio Coliving

4.5 star property
8.0 out of 10, Very Good, (409)
"The staff was friendly and very supportive."
The price is ¥6,138
¥6,752 total
includes taxes & fees
Jul 20 - Jul 21
Studio Coliving

Courtyard by Marriott Panama Metromall

4.0 star property
8.8 out of 10, Excellent, (1004)
"I really enjoyed my stay there. "
The price is ¥18,540
¥20,394 total
includes taxes & fees
Jul 20 - Jul 21
Courtyard by Marriott Panama Metromall

W Panama

5.0 star property
8.8 out of 10, Excellent, (1001)
"Beautiful hotel, highly recommend "
The price is ¥27,172
¥29,889 total
includes taxes & fees
Aug 8 - Aug 9
W Panama

TRYP by Wyndham Panamá Centro

3.5 star property
9.0 out of 10, Wonderful, (1002)
"Hotel very clean and the staff was excellent "
The price is ¥12,815
¥14,096 total
includes taxes & fees
Jul 28 - Jul 29
TRYP by Wyndham Panamá Centro

Riande Aeropuerto Hotel & Casino

4.0 star property
8.4 out of 10, Very Good, (1882)
"The rooms were clean, the breakfast was delicious and having a bar and restaurant on the premises was bonus!"
The price is ¥18,722
¥20,594 total
includes taxes & fees
Jul 25 - Jul 26
Riande Aeropuerto Hotel & Casino

Magnolia Inn

2.0 star property
9.0 out of 10, Wonderful, (359)
"We had a really great stay, great views of Casco Viejo, amazing staff, and very cozy to return to after a day out!"
The price is ¥9,071
¥9,978 total
includes taxes & fees
Jul 20 - Jul 21
Magnolia Inn

Megapolis Hotel Panamá

4.5 star property
8.4 out of 10, Very Good, (957)
"Everything was nice staff was good enjoyed my stay"
The price is ¥18,842
¥20,726 total
includes taxes & fees
Jul 20 - Jul 21
Megapolis Hotel Panamá

Panama House Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (164)
"The accommodations offered great value for the money. We appreciated the ability to bring our golden retriever, and have a parking spot in front. The owner and her staff were very friendly and helpful. The back area of the property, featuring green parrots and a blue macaw, added ambience and fun to the experience."
The price is ¥6,127
¥6,740 total
includes taxes & fees
Jul 20 - Jul 21
Panama House Bed & Breakfast

Sheraton Grand Panama

4.0 star property
8.6 out of 10, Excellent, (902)
"A great stay. "
The price is ¥18,555
¥20,411 total
includes taxes & fees
Jul 25 - Jul 26
Sheraton Grand Panama

Radisson Hotel Panama Canal

4.5 star property
8.4 out of 10, Very Good, (1000)
"very friendly staff"
The price is ¥10,499
¥11,549 total
includes taxes & fees
Jul 31 - Aug 1
Radisson Hotel Panama Canal

Best Western Plus Panama Zen Hotel

4.0 star property
9.0 out of 10, Wonderful, (891)
"Good place to stay. We enjoyed it. Breakfast was complimentary and we liked it. It was a great stay."
The price is ¥11,524
¥12,676 total
includes taxes & fees
Aug 16 - Aug 17
Best Western Plus Panama Zen Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City
Learn more about Panama City
Casco Viejo map

Casco Viejo

Unique features of Casco Viejo include the historic sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Bella Vista map

Bella Vista

1 out of top 10 points of interest in this area

Bella Vista is highly notable for its popular shops, and you might want to visit top sights like Via Espana and Iglesia del Carmen. See more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina.

El Cangrejo map

El Cangrejo

The abundant dining options and casinos are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Francisco map

San Francisco

1 out of top 10 points of interest in this area

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

Punta Paitilla map

Punta Paitilla

Travelers come to Punta Paitilla for its abundant dining options, and you can see top attractions like Avenida Balboa and Multicentro Panama while you're in town.

Learn more about Panama City

Experience Panama City: its casinos, cafes, and more!

Top Panama City Hotel Reviews

Frequently asked questions

What's the best place to stay in Panama City?

Hyatt Regency Panama City is a favorite property for Expedia customers. This hotel is a short 4-minute walk from Via Espana, and it offers a full-service spa and 2 bars. Reviews from our site also recommend Sofitel Legend Casco Viejo, Panama City and Hotel La Compania, in the Unbound Collection by Hyatt as top options for your stay. See all available top hotels, or vacation rentals in Panama City.

Casco Viejo is a top neighborhood that travelers like for its bars and historic landmarks.

What's the top vacation rental that Panama City has to offer?

Tropical House with Historic Charm, WiFi, Private Bathrooms and Workspaces: This highly rated vacation home rental in Panama City offers a balcony, a selection of games, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 6 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. Some other homes for rent in Panama City include Breathtaking Views Mansion w/King Beds and Oasis with pool near panama canal. See all vacation rentals in Panama City.

If I need to cancel my hotel reservation in Panama City, will I receive a refund?

Yes, most hotel reservations are fully refundable provided that you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Panama City.

Where can I learn more about changing or cancelling my trip to Panama City?

To access more information about rescheduling or cancelling your trip to Panama City, go to https://www.expedia.com/service/.

What's the best budget-friendly hotel in Panama City?

Based on reviews, Hotel Riu Plaza Panama is a popular hotel for our travelers who want a more economical choice, and features free buffet breakfast and free WiFi. Other choices to stay on the cheap include Principe Hotel and Suites and Hospedium Princess Hotel Panama. View all budget hotels in Panama City.

Where is the best hotel for a stay in Casco Viejo?

With 20 hotels and other accommodations to choose from in this neighborhood, you should find the perfect place for your trip. Based on Expedia customer reviews, American Trade Hotel is the highest ranked property in Casco Viejo. This 4.5-star hotel offers a restaurant and an outdoor pool. It is located a short 3-minute walk from Metropolitan Cathedral of Panama. Other top choices in the neighborhood include Magnolia Inn and Tantalo Hotel / Kitchen / Roofbar.

What's the best place to stay for a family trip to Panama City?

JW Marriott Panama is a hotel with 4 outdoor pools and 3 restaurants, and it's a top choice on Expedia for families. Other choices for your kid-friendly vacation include W Panama and Sheraton Grand Panama. Attractions like Biomuseo and Summit Botanical Gardens & Zoo are also fun for kids of all ages. Find more child-friendly accommodations in Panama City.

What's the best hotel for a romantic getaway to Panama City?

Megapolis Hotel Panamá is a favorite hotel for couples, and features a full-service spa and 2 restaurants. Other good choices for your romantic getaway include Decapolis Hotel Panama City and JW Marriott Panama. See all romantic hotels in Panama City.

What's the best LGBTQ-friendly hotel in Panama City?

Hotel Riu Plaza Panama is a top LGBTQ-friendly hotel, and features 3 restaurants and free WiFi. JW Marriott Panama and AC Hotel by Marriott Panama City are two other good options for your vacation. See all available hotels listed as LGBTQ-friendly in Panama City.

What's the best pet-friendly place to stay in Panama City?

JW Marriott Panama is a top hotel for people traveling with their pets, and offers 3 restaurants and 4 outdoor pools for its human guests. Other good options for you and your pet's trip include W Panama and Sheraton Grand Panama. See more pet-friendly hotel accommodations in Panama City.

What's the best place to stay close to Albrook Shopping Mall?

Wyndham Panama Albrook Mall Hotel & Convention Center is one of the top choices for your stay based on our traveler data, and this 4-star hotel offers 2 restaurants and 2 bars. It's located just a short 0.4 mi (0.6 km) from Albrook Shopping Mall. Another good option is GM Lodge, located just 0.3 mi (0.5 km) away.

What about the best place to stay close to Multiplaza Pacific Mall?

One of the top choices for your stay is Courtyard by Marriott Panama Multiplaza Mall, located next to Multiplaza Pacific Mall, and this 4-star hotel offers a restaurant and an outdoor pool. Hotel Riu Plaza Panama and JW Marriott Panama are other good choices nearby.

What's the best accommodation for a beach vacation in Panama City?

Akwadup Lodge is a top beachfront lodge with a restaurant, and it's located close to Veracruz Beach. See more stays near the beach in Panama City.

What's the best luxury accommodation in Panama City?

Hotel Riu Plaza Panama is a luxury hotel with 3 restaurants and valet parking, and it's a popular choice for Expedia travelers looking for an elegant place to stay. JW Marriott Panama and Megapolis Hotel Panamá are two other upscale options for your trip. Find more luxury hotels in Panama City.

What's the best boutique hotel in Panama City?

De Ville Hotel is a favorite hotel with our travelers looking for a stylish accommodation, and features 33 guestrooms, free breakfast, and free valet parking. If you'd prefer to stay at a boutique hotel, you can also take a look at Gatto Blanco Party Hotel. See all boutique hotels in Panama City.

What's the best accommodation to visit the local casinos in Panama City?

Megapolis Hotel Panamá is a top hotel featuring a casino and free stocked minibars. Other good options to try your luck include Decapolis Hotel Panama City and Hilton Panama. See more casino hotels in Panama City.

Where is the best area of Panama City for tourists?

Casco Viejo is one of the best areas of the city for sightseeing with 15 places to visit including Metropolitan Cathedral of Panama, Interoceanic Canal Museum, and Casco viejo panama basilica.

What are some accommodations with pools in Panama City?

JW Marriott Panama is a top hotel with 4 outdoor pools, a children's pool, and 3 restaurants. A couple of other options that feature an onsite pool include Sheraton Grand Panama and TRYP by Wyndham Panamá Centro. View all hotels with pools in Panama City.

What is the best spa hotel in Panama City?

Waymore Hotel Spa & Casino is a top spa hotel featuring a bar, an outdoor pool, and a restaurant. Treat yourself to a facial, body scrub, or Swedish massage at the onsite spa. Other popular spa hotels in Panama City include Megapolis Hotel Panamá and W Panama. See all spa hotels in Panama City.

What is the best hotel near Tocumen International Airport (PTY)?

Crowne Plaza Panama Airport is a popular 4-star hotel featuring a restaurant and an outdoor pool. It's located a short 0.3 mi (0.4 km) from Tocumen Intl. Airport. Other good options within close proximity to the airport include Riande Aeropuerto Hotel & Casino and Express Inn Panama International Airport Hostel.

How is it to stay in Panama City?

Travelers to Panama City give high marks for the shopping, casinos, and top-notch restaurants. Tourists who journey to this scenic city can discover its cafes, bars, and local tours. A top sight in the city is Albrook Shopping Mall. In Panama City, there are 1304 hotels and other accommodations to choose from. Find out more about Panama City.

What should I do while I'm visiting Panama City?

Cultural venues include National Theater, Interoceanic Canal Museum, and Biomuseo. Landmarks like Iglesia del Carmen, Calle 50, and Metropolitan Cathedral of Panama might be worth a visit. Natural beauty is on display at Cinta Costera, Miraflores Locks, and Metropolitan Nature Park. Check out what more to see and do in Expedia's Panama City guide.

How can I get around Panama City?

You can walk to nearby metro stations including Iglesia del Carmen Station, Vía Argentina, and Santo Tomas Station. If you want to explore the larger area, hop aboard a train at Panama City Passenger Station. If you want to venture out around the area, you may want a rental car in Panama City for your journey.

What's the weather like in Panama City?

The hottest months are usually March and April with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in Panama City are July, August, June, and November, with each month seeing an average of 15 inches of rainfall.