Ladys Island Adults Only Vacations 2026

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Top Adults Only Ladys Island Hotels

Close to Beaches, Parris Island & Pet friendly-on Lady's Island!

Beaufort SC

6 min drive from Coosaw Island

Stay at this apartment in Beaufort. Enjoy free WiFi, patios, and cable/satellite TV service. Popular attractions Bay Street and USCB Center for the Arts are ...

10/10 Exceptional! (121 reviews)

"I really enjoyed our stay on Lady’s Island! The home was very clean, comfortable, and conveniently located close to everything we needed, while still being a nice place to relax. The location made it easy to get around and enjoy the area. We would definitely recommend this VRBO to others visiting ..."

Reviewed on Aug 16, 2026

See all 12,047 properties in Ladys Island

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.