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Find Family Hotels in Upstate South Carolina, SC

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Check availability on Upstate South Carolina Family Hotels

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Our top choices for Upstate South Carolina family-friendly hotels

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.6 out of 10, Excellent, (425)
"Great place to stay"
United States
Timothy
The price is ¥12,212
¥13,310 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Holiday Inn Express Gaffney by IHG

DoubleTree by Hilton Greenville Woodruff Road

DoubleTree by Hilton Greenville Woodruff Road
3.0 star property
Greenville
9.4 out of 10, Exceptional, (1001)
"Clean modern comfortable convenient location great cookie "
United States
Jimmy
The price is ¥17,514
¥19,266 total
includes taxes & fees
Dec 30 - Dec 31
DoubleTree by Hilton Greenville Woodruff Road

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
2.5 star property
Greenville
9.0 out of 10, Wonderful, (1425)
"Clean room, great selection for breakfast, easy check in and check out"
United States
Angelica
The price is ¥13,388
¥14,726 total
includes taxes & fees
Dec 30 - Dec 31
Best Western Plus Greenville I-385 Inn & Suites

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1006)
"Great hospitality and clean rooms"
United States
Roger
The price is ¥15,406
¥16,947 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Embassy Suites Greenville Golf Resort & Conference Center

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
2.5 star property
Seneca
9.4 out of 10, Exceptional, (204)
"Nice hotel by the lake"
United States
Mike
The price is ¥18,006
¥19,806 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Fairfield Inn & Suites Seneca Clemson Univ Area

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (785)
"Everything was clean staff was courteous and accommodating. "
United States
Stewart
The price is ¥23,329
¥25,895 total
includes taxes & fees
Dec 29 - Dec 30
The Inn at Patrick Square

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (665)
"Friendly check in, clean room."
United States
connie
The price is ¥11,508
¥13,591 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn Seneca Clemson Area US-123

SpringHill Suites by Marriott Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown
2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1002)
"Great spot and beautiful hotel!"
United States
Lisa
The price is ¥19,587
¥21,547 total
includes taxes & fees
Jan 25 - Jan 26, 2026
SpringHill Suites by Marriott Greenville Downtown

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (673)
"Clean room, great staff."
United States
gary
The price is ¥15,278
¥16,653 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Hampton Inn Gaffney

La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood
3.0 star property
Greenville
7.4 out of 10, Good, (1130)
"Kind staff, clean room, tasty continental breakfast!"
United States
Karen
The price is ¥11,132
¥12,245 total
includes taxes & fees
Dec 30 - Dec 31
La Quinta Inn & Suites by Wyndham Greenville Haywood
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Upstate South Carolina Hotel Reviews

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