Photo by Michelle Hendrix

Find hotels in Upstate South Carolina, SC from ¥10,621

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Compare 2,908 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Embassy Suites Greenville Golf Resort & Conference Center

3.5 star property
Greenville
9.0 out of 10, Wonderful, (1006)
" The property was really great amazing clean great breakfast"
United States
Dallas
The price is ¥14,290
¥15,718 total
includes taxes & fees
Dec 21 - Dec 22
Embassy Suites Greenville Golf Resort & Conference Center

DoubleTree by Hilton Greenville Woodruff Road

3.0 star property
Greenville
9.4 out of 10, Exceptional, (1002)
"The hotel was excellent m."
United States
Brittiany
The price is ¥16,372
¥18,010 total
includes taxes & fees
Dec 21 - Dec 22
DoubleTree by Hilton Greenville Woodruff Road

ECHO Suites Extended Stay by Wyndham Spartanburg

2.0 star property
Spartanburg
8.2 out of 10, Very Good, (289)
"Nice hotel "
United States
Kierra
The price is ¥11,223
¥12,706 total
includes taxes & fees
Dec 22 - Dec 23
ECHO Suites Extended Stay by Wyndham Spartanburg

Hyatt Place Greenville/Haywood

3.0 star property
Greenville
7.8 out of 10, Good, (1006)
"Slightly better than your average hotel- clean, updated rooms, decent amenities, typical sub par breakfast. "
United States
Kierstin
The price is ¥12,675
¥13,943 total
includes taxes & fees
Dec 22 - Dec 23
Hyatt Place Greenville/Haywood

Quality Inn & Suites Greenville - Haywood Mall

2.5 star property
Greenville
7.4 out of 10, Good, (1005)
"The room was clean and staff very courteous. Breakfast was very good pork sausage, eggs and sausage gravy, A good hot breakfast makes me a return customer."
United States
Edward or Rosemarie
The price is ¥10,345
¥11,845 total
includes taxes & fees
Dec 10 - Dec 11
Quality Inn & Suites Greenville - Haywood Mall

Hyatt Regency Greenville

3.5 star property
Greenville Downtown
8.6 out of 10, Excellent, (1011)
"Staff was very friendly. "
United States
Kristin
The price is ¥20,992
¥23,784 total
includes taxes & fees
Dec 21 - Dec 22
Hyatt Regency Greenville

Drury Inn & Suites Greenville

3.0 star property
Greenville
9.6 out of 10, Exceptional, (1012)
"Very nice amenities and rooms. Staff was super friendly and very helpful when needed. We will definitely stay at another Drury Inn when traveling or needing a hotel"
United States
Blair
The price is ¥17,240
¥18,964 total
includes taxes & fees
Dec 14 - Dec 15
Drury Inn & Suites Greenville

Homewood Suites by Hilton Greenville Downtown

3.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1007)
"Great stay."
United States
Mitchell
The price is ¥18,515
¥20,924 total
includes taxes & fees
Dec 19 - Dec 20
Homewood Suites by Hilton Greenville Downtown

Holiday Inn Express & Suites Greenville - Downtown by IHG

2.5 star property
Greenville Downtown
8.8 out of 10, Excellent, (1002)
"Great location, very friendly staff, nice room"
United States
Coltin
The price is ¥16,776
¥18,454 total
includes taxes & fees
Dec 19 - Dec 20
Holiday Inn Express & Suites Greenville - Downtown by IHG

Aloft Greenville Downtown

3.0 star property
Greenville Downtown
9.0 out of 10, Wonderful, (1001)
"Perfect place to stay!"
United States
Stephanie
The price is ¥19,460
¥21,407 total
includes taxes & fees
Dec 15 - Dec 16
Aloft Greenville Downtown

SpringHill Suites by Marriott Greenville Downtown

2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1002)
"Loved our stay. Comfortable in every way. Close to all the sites and Christmas fun. Great Breakfast "
United States
Matthew
The price is ¥18,352
¥20,186 total
includes taxes & fees
Jan 1 - Jan 2, 2026
SpringHill Suites by Marriott Greenville Downtown

Days Inn by Wyndham Anderson

2.0 star property
Anderson
7.8 out of 10, Good, (1001)
"Very nice we'll stay there again"
United States
Michael
The price is ¥9,770
¥10,846 total
includes taxes & fees
Dec 11 - Dec 12
Days Inn by Wyndham Anderson

Woodspring Suites Greenville Airport

2.5 star property
Greenville
8.2 out of 10, Very Good, (298)
"Clean room, friendly staff, I would definitely stay here again!"
United States
Melissa
The price is ¥12,271
¥13,498 total
includes taxes & fees
Dec 11 - Dec 12
Woodspring Suites Greenville Airport

Hampton Inn & Suites Greenville-Downtown-RiverPlace

2.5 star property
Greenville Downtown
9.4 out of 10, Exceptional, (1008)
"Clean room great atmosphere and friendly staff. "
United States
Hubert
The price is ¥18,515
¥20,923 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites Greenville-Downtown-RiverPlace

Hotel Hartness

4.0 star property
Greenville
9.8 out of 10, Exceptional, (624)
"Beautiful location, friendly staff"
United States
Andrew
The price is ¥23,508
¥31,104 total
includes taxes & fees
Dec 15 - Dec 16
Hotel Hartness

Comfort Inn Greenville - Haywood Mall

2.5 star property
Greenville
8.0 out of 10, Very Good, (1003)
"Staff was very friendly, clean rooms, only downside is I ended up being sick during my trip and had to spend some time in the room to relax, but the tv didn’t work :( "
United States
Amanda
The price is ¥13,141
¥14,921 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Inn Greenville - Haywood Mall

Home2 Suites by Hilton Greenville Downtown

3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1002)
"Great shopping nearby"
United States
Jordan
The price is ¥16,651
¥18,317 total
includes taxes & fees
Dec 21 - Dec 22
Home2 Suites by Hilton Greenville Downtown

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

2.5 star property
Spartanburg
8.6 out of 10, Excellent, (861)
"The stay was great overall, room was exceptional in size and comfort. The noise from the highway was the only distraction but mainly because we do not ever have any. The staff was friendly and helpful. We would not hesitate to stay here again."
United States
Charmaine
The price is ¥15,067
¥16,724 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Sleep Inn at Greenville Convention Cente

2.5 star property
Greenville
8.0 out of 10, Very Good, (1001)
"The room and the hotel is showing it's age. The room and hotel were clean."
United States
Marian
The price is ¥13,579
¥15,373 total
includes taxes & fees
Dec 11 - Dec 12
Sleep Inn at Greenville Convention Cente

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
Greenville
9.0 out of 10, Wonderful, (1420)
"Clean room, great selection for breakfast, easy check in and check out"
United States
Angelica
The price is ¥14,539
¥15,993 total
includes taxes & fees
Dec 22 - Dec 23
Best Western Plus Greenville I-385 Inn & Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Upstate South Carolina, SC

Showing deals for:Dec 19 - Dec 21
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

The view from Caesars Head after a storm
Photo by Michelle Hendrix
Open Photo by Michelle Hendrix

Top Upstate South Carolina Hotel Reviews

More cheap stays in Upstate South Carolina

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia