Find 4 Star Hotels in Upstate South Carolina, SC from ￥19,647

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Check availability on Upstate South Carolina 4 Star Hotels

Tonight
Sep 27 - Sep 28
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Sep 28 - Sep 29
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Oct 3 - Oct 5
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Oct 10 - Oct 12

Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (388)
"Beautiful hotel with views of the Reedy River and Falls. "
The price is ￥38,935
￥43,996 total
includes taxes & fees
Oct 26 - Oct 27
Grand Bohemian Lodge Greenville, Autograph Collection
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (689)
"Great staff, location, comfortable and well maintained property."
The price is ￥28,254
￥31,362 total
includes taxes & fees
Oct 19 - Oct 20
The Shepherd Hotel Downtown Clemson
The Westin Poinsett Greenville
Meeting facility

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1006)
"We visited Greenville for a wedding and our stay at the Westin was perfect!"
The price is ￥25,308
￥27,839 total
includes taxes & fees
Sep 28 - Sep 29
The Westin Poinsett Greenville
Mint House Greenville - Downtown
Two Bedroom Suite | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (736)
"It was very clean and conveniently located. "
The price is ￥17,386
￥19,647 total
includes taxes & fees
Sep 28 - Sep 29
Mint House Greenville - Downtown
Hotel Hartness
Restaurant

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (595)
"amazing place and great visit to area"
The price is ￥23,963
￥31,413 total
includes taxes & fees
Oct 12 - Oct 13
Hotel Hartness
Greenville Marriott
Premium bedding, down comforters, pillowtop beds, in-room safe

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (593)
"we enjoyed the bar"
The price is ￥19,168
￥21,716 total
includes taxes & fees
Oct 12 - Oct 13
Greenville Marriott
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (542)
"Customer service was above and beyond, whenever we travel through Clemson again, we will only stay at The Abernathy!"
The Abernathy of Clemson
Park Place Apartments by Landing
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels

Park Place Apartments by Landing

4.0 star property
7.8 out of 10, Good, (40)
"Great place for a different experience Enjoyed the train "
Park Place Apartments by Landing
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (12)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is ￥25,329
￥40,194 total
includes taxes & fees
Oct 1 - Oct 2
The Station by Compo Hotels
Liberty Hall Bed and Breakfast
Restaurant

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (74)
"Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! "
Liberty Hall Bed and Breakfast
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is ￥68,735
￥75,609 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"Everything! Beautiful, convenient and wonderful staff!"
Jessica 1-night trip
Posted 2 days ago
The Shepherd Hotel Downtown Clemson
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"This an excellent property in a very good location, both for the natural surroundings, and the proximity to restaurants, shopping, and sightseeing."
Robert 4-night trip
Posted 4 days ago
Grand Bohemian Lodge Greenville, Autograph Collection

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from ￥19,647

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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