Find 4 Star Hotels in Upstate South Carolina, SC from ¥18,657

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Check availability on Upstate South Carolina 4 Star Hotels

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Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (386)
"Beautiful hotel with views of the Reedy River and Falls. "
The price is ¥39,799
¥44,973 total
includes taxes & fees
Sep 28 - Sep 29
Grand Bohemian Lodge Greenville, Autograph Collection

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (684)
"Great staff, location, comfortable and well maintained property."
The price is ¥27,963
¥31,039 total
includes taxes & fees
Sep 29 - Sep 30
The Shepherd Hotel Downtown Clemson

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1004)
"We visited Greenville for a wedding and our stay at the Westin was perfect!"
The price is ¥25,004
¥27,504 total
includes taxes & fees
Sep 28 - Sep 29
The Westin Poinsett Greenville

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (732)
"It was very clean and conveniently located. "
The price is ¥16,511
¥18,657 total
includes taxes & fees
Sep 28 - Sep 29
Mint House Greenville - Downtown

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (589)
"Beautiful property everything was excellent !"
The price is ¥23,716
¥31,088 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Hartness

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (592)
"we enjoyed the bar"
The price is ¥18,938
¥21,456 total
includes taxes & fees
Sep 28 - Sep 29
Greenville Marriott

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (542)
"Customer service was above and beyond, whenever we travel through Clemson again, we will only stay at The Abernathy!"
The Abernathy of Clemson

Park Place Apartments by Landing

4.0 star property
7.8 out of 10, Good, (38)
"Great place for a different experience Enjoyed the train "
Park Place Apartments by Landing

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (12)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is ¥27,398
¥42,344 total
includes taxes & fees
Sep 22 - Sep 23
The Station by Compo Hotels

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (74)
"Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! "
Liberty Hall Bed and Breakfast

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is ¥67,909
¥74,700 total
includes taxes & fees
Sep 22 - Sep 23
Hotel Domestique

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat

228 Lakeland

4.0 star property
228 Lakeland
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from ¥18,657

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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