Find 4 Star Hotels in Upstate South Carolina, SC from ￥18,657

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Check availability on Upstate South Carolina 4 Star Hotels

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Sep 20 - Sep 21
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Sep 21 - Sep 22
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Sep 26 - Sep 28
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Oct 3 - Oct 5

Compare Upstate South Carolina 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Grand Bohemian Lodge Greenville, Autograph Collection
Lobby

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
9.6 out of 10, Exceptional, (386)
"Beautiful hotel with views of the Reedy River and Falls. "
The price is ￥39,799
￥44,973 total
includes taxes & fees
Sep 28 - Sep 29
Grand Bohemian Lodge Greenville, Autograph Collection
The Shepherd Hotel Downtown Clemson
Superior Room, 2 Queen Beds | In-room safe, blackout drapes, soundproofing, iron/ironing board

The Shepherd Hotel Downtown Clemson

4.0 star property
9.8 out of 10, Exceptional, (684)
"Great staff, location, comfortable and well maintained property."
The price is ￥27,963
￥31,039 total
includes taxes & fees
Sep 29 - Sep 30
The Shepherd Hotel Downtown Clemson
The Westin Poinsett Greenville
Meeting facility

The Westin Poinsett Greenville

4.0 star property
9.2 out of 10, Wonderful, (1004)
"We visited Greenville for a wedding and our stay at the Westin was perfect!"
The price is ￥25,004
￥27,504 total
includes taxes & fees
Sep 28 - Sep 29
The Westin Poinsett Greenville
Mint House Greenville - Downtown
Two Bedroom Suite | 3 bedrooms, laptop workspace, iron/ironing board, free WiFi

Mint House Greenville - Downtown

4.0 star property
9.2 out of 10, Wonderful, (732)
"It was very clean and conveniently located. "
The price is ￥16,511
￥18,657 total
includes taxes & fees
Sep 28 - Sep 29
Mint House Greenville - Downtown
Hotel Hartness
Restaurant

Hotel Hartness

4.0 star property
9.8 out of 10, Exceptional, (589)
"Beautiful property everything was excellent !"
The price is ￥23,716
￥31,088 total
includes taxes & fees
Sep 28 - Sep 29
Hotel Hartness
Greenville Marriott
Premium bedding, down comforters, pillowtop beds, in-room safe

Greenville Marriott

4.0 star property
8.6 out of 10, Excellent, (592)
"we enjoyed the bar"
The price is ￥18,938
￥21,456 total
includes taxes & fees
Sep 28 - Sep 29
Greenville Marriott
The Abernathy of Clemson
Meeting facility

The Abernathy of Clemson

4.0 star property
9.6 out of 10, Exceptional, (542)
"Customer service was above and beyond, whenever we travel through Clemson again, we will only stay at The Abernathy!"
The Abernathy of Clemson
Park Place Apartments by Landing
Apartment, 2 Bedrooms | Living area | 40-inch TV with digital channels

Park Place Apartments by Landing

4.0 star property
7.8 out of 10, Good, (38)
"Great place for a different experience Enjoyed the train "
Park Place Apartments by Landing
The Station by Compo Hotels
Trailside Wedge Cottage | Terrace/patio

The Station by Compo Hotels

4.0 star property
10.0 out of 10, Exceptional, (12)
"Beautiful rooms and surroundings. Less than 5 minutes from Furman university and really close to delightful and quirky travelers rest! Great place to stay!"
The price is ￥27,398
￥42,344 total
includes taxes & fees
Sep 22 - Sep 23
The Station by Compo Hotels
Liberty Hall Bed and Breakfast
Restaurant

Liberty Hall Bed and Breakfast

4.0 star property
10.0 out of 10, Exceptional, (74)
"Beautiful home, very clean, easy self check in. I unfortunately was not able to join breakfast during my stay, but the host gave me a goodie bag to go, which was much appreciated! "
Liberty Hall Bed and Breakfast
Hotel Domestique
Bar (on property)

Hotel Domestique

4.0 star property
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
The price is ￥67,909
￥74,700 total
includes taxes & fees
Sep 22 - Sep 23
Hotel Domestique
Southern Sunshine Retreat
42-inch flat-screen TV with digital channels

Southern Sunshine Retreat

4.0 star property
Southern Sunshine Retreat
228 Lakeland
Dock

228 Lakeland

4.0 star property
228 Lakeland
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Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

See all hotels in Upstate South Carolina
Greenville - Spartanburg showing a sunset, tranquil scenes and mountains
Photo by South Carolina Department of Parks, Recreation & Tourism
Open Photo by South Carolina Department of Parks, Recreation & Tourism

Top Upstate South Carolina Hotel Reviews

Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

10/10 Excellent
"Gorgeous property with over the top extras and amenities. Just booked a future stay for my son and his wife who will be visiting from Oklahoma in January, so they can experience this beautiful place."
Jane 2-night trip
Posted 3 days ago
Grand Bohemian Lodge Greenville, Autograph Collection
The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"I literally want to live at this hotel. The pervice is impecable. The attention to detail is incredible. Cant say enough about every aspect. Wish i could give 10 star's "
Poe 2-night trip
Posted 9 days ago
The Shepherd Hotel Downtown Clemson

Frequently asked questions

What are the best 4-star hotels in Upstate South Carolina?
Stay at Greenville Marriott and get ready for upscale comfort and plenty of handy amenities. This 4-star hotel in Greer, Upstate South Carolina, is highly recommended by Expedia guests.
How much does it cost to stay in a 4-star hotel in Upstate South Carolina?
Expedia can help you quickly locate the perfect 4-star hotel for your getaway in Upstate South Carolina. Use our handy filter tool to tailor your search by things like amenities, budget and property star rating and get access to fabulous deals in a few clicks.

  • Search for the lowest price from ￥18,657

What's the difference between 5-star and 4-star hotels in Upstate South Carolina?
Offering a friendly guest experience and upmarket décor, 4-star hotels are a wonderful option for your Upstate South Carolina trip. These kinds of accommodations generally come with loads of handy amenities that make it simple to kick back and relax — think large beds, bathrobes, restaurants and pools. Or live the high life at a 5-star hotel designed to pamper with exclusive perks and amenities. Full-service health clubs, premium toiletries and fine dining are typically featured at these deluxe retreats.

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