Find hotels in Upstate South Carolina, SC from ¥10,898

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Upstate South Carolina hotels

Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (2 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
The price is ¥14,986
¥29,625 total
includes taxes & fees
Mar 2 - Mar 3
Carolina Camp Cedar

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (681 reviews)
"Everting was good"
United States
Susan
The price is ¥12,152
¥14,316 total
includes taxes & fees
Mar 7 - Mar 8
Quality Inn Seneca Clemson Area US-123

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (449 reviews)
"Great people n place"
United States
Janice
The price is ¥11,860
¥12,929 total
includes taxes & fees
Mar 8 - Mar 9
Holiday Inn Express Gaffney by IHG

Hampton Inn Easley

Hampton Inn Easley
2.5 star property
Easley
9.2 out of 10, Wonderful, (691 reviews)
"Friendly staff, very comfortable room, excellent hot breakfast."
United States
Thomas
The price is ¥19,066
¥21,163 total
includes taxes & fees
Mar 8 - Mar 9
Hampton Inn Easley

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
Clemson
9.4 out of 10, Exceptional, (978 reviews)
"Everything was very nice "
United States
Paige
The price is ¥23,251
¥25,809 total
includes taxes & fees
Mar 2 - Mar 3
Clemson University's James F. Martin Inn

Fairfield Inn & Suites by Marriott Greenville Simpsonville

Fairfield Inn & Suites by Marriott Greenville Simpsonville
3.0 star property
Simpsonville
9.0 out of 10, Wonderful, (680 reviews)
"Quick check in, and the rooms were clean!"
United States
DENNIS
The price is ¥15,761
¥17,337 total
includes taxes & fees
Mar 2 - Mar 3
Fairfield Inn & Suites by Marriott Greenville Simpsonville

Comfort Inn & Suites Greer - Greenville

Comfort Inn & Suites Greer - Greenville
2.5 star property
Greer
8.6 out of 10, Excellent, (763 reviews)
"this is the best hotel friendly clean rooms, quiet and the staff is great."
United States
pamela
The price is ¥13,778
¥15,430 total
includes taxes & fees
Mar 22 - Mar 23
Comfort Inn & Suites Greer - Greenville

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is ¥17,009
¥21,115 total
includes taxes & fees
Mar 2 - Mar 3
Lakeside Lodge Clemson

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,006 reviews)
"Our room was very clean and the staff were very nice and courteous!"
United States
Tina
The price is ¥14,232
¥15,796 total
includes taxes & fees
Mar 5 - Mar 6
Best Western Plus Clemson Hotel & Conference Center

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (810 reviews)
"Perfect stay for a weekend. Lots of shopping and restaurants nearby. Clean safe area annd the staff was wonderful!"
United States
Cindy
The price is ¥17,403
¥19,144 total
includes taxes & fees
Mar 9 - Mar 10
Tru by Hilton Seneca Clemson

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
Clemson
9.8 out of 10, Exceptional, (801 reviews)
"Clean room, great location, wonderful staff!"
United States
Joyce
The price is ¥23,251
¥25,809 total
includes taxes & fees
Mar 2 - Mar 3
The Inn at Patrick Square

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,001 reviews)
"Room was extremely clean, continental breakfast was amazing with many options, and staff were very friendly. Great hotel! "
United States
Delaney
The price is ¥15,121
¥16,785 total
includes taxes & fees
Mar 8 - Mar 9
Comfort Inn & Suites Clemson - University Area

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (597 reviews)
"Clean, quiet, comfortable stay- staff is always friendly and helpful!"
United States
Lori
The price is ¥14,513
¥16,110 total
includes taxes & fees
Mar 22 - Mar 23
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Inn @ Clemson

Inn @ Clemson
2.5 star property
Clemson
8.2 out of 10, Very Good, (1,003 reviews)
"Staff and hotel was amazing "
United States
Keren
Inn @ Clemson

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (682 reviews)
"Excellent all around "
United States
Anthony
The price is ¥18,080
¥19,706 total
includes taxes & fees
Mar 22 - Mar 23
Hampton Inn Gaffney

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (703 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is ¥15,500
¥17,205 total
includes taxes & fees
Mar 7 - Mar 8
Hilton Garden Inn Anderson

Hotel Hartness

Hotel Hartness
4.0 star property
Greenville
9.8 out of 10, Exceptional, (660 reviews)
"The hotel was clean staff was amazing room was outstanding."
United States
Clifford
The price is ¥23,624
¥31,255 total
includes taxes & fees
Mar 8 - Mar 9
Hotel Hartness

Hampton Inn Greer Greenville, SC

Hampton Inn Greer Greenville, SC
2.5 star property
Greer
9.6 out of 10, Exceptional, (434 reviews)
"Parking garage for hotel guests, location was great, hotel was clean, staff was great. "
United States
Tyler
The price is ¥24,812
¥27,045 total
includes taxes & fees
Mar 16 - Mar 17
Hampton Inn Greer Greenville, SC

Spartanburg Marriott

Spartanburg Marriott
3.5 star property
Spartanburg
8.6 out of 10, Excellent, (1,000 reviews)
"great hotel! Clean and awesome restaurant!"
United States
Alicia
The price is ¥18,414
¥20,438 total
includes taxes & fees
Mar 15 - Mar 16
Spartanburg Marriott

Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
3.0 star property
Spartanburg
9.4 out of 10, Exceptional, (455 reviews)
"Friendly staff, clean rooms, excellent food! "
United States
Ashley
The price is ¥15,785
¥17,522 total
includes taxes & fees
Mar 8 - Mar 9
Four Points by Sheraton Spartanburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Vacation Rentals in Upstate South Carolina

Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Southeastern United States attractions

Learn more about Upstate South Carolina

Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Greenville - Spartanburg
Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina

Top Upstate South Carolina Hotel Reviews

More cheap stays in Upstate South Carolina

Hotels in Upstate South Carolina with star-rating

Explore a world of travel with Expedia