Photo by Visit Greenville, South Carolina

Find hotels in Upstate South Carolina, SC from ¥10,393
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Go beyond your typical stay in Upstate South Carolina
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Our top choices for Upstate South Carolina hotels

1. Carolina Inn Anderson Clemson Area
Carolina Inn Anderson Clemson AreaAnderson
10.0 out of 10, Exceptional, (2 reviews)
The price is ¥8,781
¥9,747 total
includes taxes & fees
Jun 15 - Jun 16

2. Hampton Inn Gaffney
Hampton Inn GaffneyGaffney
8.8 out of 10, Excellent, (726 reviews)
The price is ¥13,283
¥14,477 total
includes taxes & fees
Jun 28 - Jun 29

3. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHGAnderson
9.2 out of 10, Wonderful, (622 reviews)
The price is ¥16,955
¥18,820 total
includes taxes & fees
Jul 3 - Jul 4

4. Fairfield Inn & Suites Seneca Clemson Univ Area
Fairfield Inn & Suites Seneca Clemson Univ AreaSeneca
9.4 out of 10, Exceptional, (234 reviews)
The price is ¥20,638
¥22,701 total
includes taxes & fees
Jun 16 - Jun 17

5. Quality Inn Seneca Clemson Area US-123
Quality Inn Seneca Clemson Area US-123Downtown
8.0 out of 10, Very Good, (708 reviews)
The price is ¥13,524
¥15,883 total
includes taxes & fees
Jun 6 - Jun 7

6. Hampton Inn Greer Greenville, SC
Hampton Inn Greer Greenville, SCGreer
9.6 out of 10, Exceptional, (462 reviews)
The price is ¥22,233
¥24,234 total
includes taxes & fees
Jun 6 - Jun 7

7. Deluxe Inn
Deluxe InnMauldin
9.4 out of 10, Exceptional, (3 reviews)
The price is ¥9,656
¥10,620 total
includes taxes & fees
Jun 4 - Jun 5

8. Lakeside Lodge Clemson
Lakeside Lodge ClemsonSeneca
9.0 out of 10, Wonderful, (1,003 reviews)
The price is ¥17,402
¥21,603 total
includes taxes & fees
Jun 18 - Jun 19

9. Carolina Camp Cedar
Carolina Camp CedarPickens
10.0 out of 10, Exceptional, (3 reviews)
The price is ¥25,362
¥41,442 total
includes taxes & fees
Jun 4 - Jun 5

10. The Shepherd Hotel Downtown Clemson
The Shepherd Hotel Downtown ClemsonClemson
9.8 out of 10, Exceptional, (809 reviews)
The price is ¥21,612
¥23,989 total
includes taxes & fees
Jun 15 - Jun 16

11. Hampton Inn Easley
Hampton Inn EasleyEasley
9.2 out of 10, Wonderful, (714 reviews)
The price is ¥19,543
¥21,693 total
includes taxes & fees
Jun 21 - Jun 22

12. Tru by Hilton Seneca Clemson
Tru by Hilton Seneca ClemsonSeneca
9.2 out of 10, Wonderful, (845 reviews)
The price is ¥16,920
¥18,611 total
includes taxes & fees
Jul 3 - Jul 4

13. Holiday Inn Express Gaffney by IHG
Holiday Inn Express Gaffney by IHGGaffney
8.8 out of 10, Excellent, (492 reviews)
The price is ¥13,251
¥14,443 total
includes taxes & fees
Jun 14 - Jun 15

14. The Inn at Patrick Square
The Inn at Patrick SquareClemson
9.8 out of 10, Exceptional, (857 reviews)
The price is ¥23,788
¥26,405 total
includes taxes & fees
Jun 16 - Jun 17

15. Best Western Plus Greenville I-385 Inn & Suites
Best Western Plus Greenville I-385 Inn & SuitesGreenville
9.2 out of 10, Wonderful, (1,489 reviews)
The price is ¥14,555
¥16,011 total
includes taxes & fees
Jun 14 - Jun 15

16. Clemson University's James F. Martin Inn
Clemson University's James F. Martin InnClemson
9.4 out of 10, Exceptional, (1,000 reviews)
The price is ¥22,233
¥24,679 total
includes taxes & fees
Jun 8 - Jun 9

17. Microtel Inn & Suites by Wyndham Anderson/Clemson
Microtel Inn & Suites by Wyndham Anderson/ClemsonAnderson
8.4 out of 10, Very Good, (1,004 reviews)
The price is ¥12,892
¥14,311 total
includes taxes & fees
Jun 19 - Jun 20

18. The Abernathy of Clemson
The Abernathy of ClemsonClemson
9.6 out of 10, Exceptional, (602 reviews)
The price is ¥21,236
¥23,571 total
includes taxes & fees
Jul 1 - Jul 2

19. Best Western Spartanburg Northwest
Best Western Spartanburg NorthwestSpartanburg
8.4 out of 10, Very Good, (913 reviews)
The price is ¥14,113
¥15,666 total
includes taxes & fees
Jun 16 - Jun 17

20. Embassy Suites Greenville Golf Resort & Conference Center
Embassy Suites Greenville Golf Resort & Conference CenterGreenville
9.0 out of 10, Wonderful, (1,238 reviews)
The price is ¥19,866
¥21,853 total
includes taxes & fees
Jun 7 - Jun 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in Upstate South Carolina
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott BonvoySeneca
9.8 out of 10, Exceptional, (76 reviews)
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Stay near popular Upstate South Carolina attractions
Learn more about Upstate South Carolina
Experience the family-friendly area of Upstate South Carolina—live music, restaurants, and sights from Discovery Island Water Park to Frankie's Fun Park.

Photo by Visit Greenville, South Carolina
Open Photo by Visit Greenville, South Carolina
Top Upstate South Carolina Hotel Reviews

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown
4/10 Poor
More cheap stays in Upstate South Carolina

Sleep Inn Spartanburg Southwest
501 South Blackstock Rd Spartanburg SC
The price is ¥9,363 per night from Jun 28 to Jun 29
¥9,363
¥10,393 total
Jun 28 - Jun 29
includes taxes & fees
6/10 (611 reviews)
Hotels in Upstate South Carolina with star-rating

4 Star Hotels
39 properties
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