Upstate South Carolina, SC

Travel Guide

Photo provided by South Carolina Department of Parks, Recreation & Tourism
Photo provided by Visit Greenville, South Carolina
Photo provided by South Carolina Department of Parks, Recreation & Tourism
Photo provided by Visit Greenville, South Carolina
Photo provided by Visit Greenville, South Carolina

Where to stay in Upstate South Carolina

Greenville featuring autumn leaves, a garden and a bridge

Greenville Downtown

5/5(654 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Greenville Downtown
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Nicholtown

If you're spending some time in Nicholtown, Pleasantburg Shopping Center and Swamp Rabbit Trail are top sights worth seeing.

Nicholtown
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West End

Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river.

West End
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Turtlehead

If you're spending some time in Turtlehead, Lake Keowee and Chapman Bridge Oconee Bell Preserve are top sights worth seeing.

Turtlehead
Greenville - Spartanburg showing a sunset, tranquil scenes and mountains

Overbrook Historic District

While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House.

Overbrook Historic District
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Green Avenue

If you're looking for some top things to see and do in Green Avenue and surrounding area, you can visit Fluor Field at the West End and The Peace Center.

Green Avenue
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
The price is ¥13,983 per night from Aug 22 to Aug 23
¥13,983
¥15,381 total
Aug 22 - Aug 23
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, free parking, and 2 restaurants. Our guests praise the helpful staff and the room ...
8.4/10 Very Good! (1,001 reviews)
"Very firm bed. Excellent accessibility options."

Reviewed on Aug 16, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
The price is ¥19,871 per night from Aug 24 to Aug 25
¥19,871
¥22,514 total
Aug 24 - Aug 25
includes taxes & fees
Book a stay at this business-friendly hotel in Greenville. Enjoy free WiFi, an outdoor pool, and breakfast (surcharge). Our guests praise the helpful staff and ...
8.6/10 Excellent! (1,003 reviews)
"The restaurant was under construction and had limited menu and no food service at bar The food I had was very tasty"

Reviewed on Aug 11, 2025

Hyatt Regency Greenville
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
The price is ¥12,033 per night from Aug 21 to Aug 22
¥12,033
¥13,633 total
Aug 21 - Aug 22
includes taxes & fees
Stay at this 3.5-star business-friendly hotel in Greenville. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and ...
8/10 Very Good! (1,003 reviews)
"Everything was excellent."

Reviewed on Aug 15, 2025

Hilton Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mint House Greenville - Downtown

Mint House Greenville - Downtown

4 out of 5
101 Falls Park Dr, Greenville, SC
Stay at this 4-star apartment in Greenville. Enjoy free WiFi, a 24-hour fitness center, and laundry facilities. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (712 reviews)
"Absolutely excellent location - only a block away from everything in downtown Greenville. Great setup with everything you need in the apartment. Highly recommend it."

Reviewed on Aug 13, 2025

Mint House Greenville - Downtown
Wooded Cottage - 3 Mi to Clemson University

Wooded Cottage - 3 Mi to Clemson University

3 out of 5
Clemson
Stay at this 3-star cottage in Clemson. Enjoy free parking and air conditioning. Popular attractions Clemson Area African American Museum and Larry W. Abernathy ...
Wooded Cottage - 3 Mi to Clemson University
Postcard Cabins Lake Hartwell

Postcard Cabins Lake Hartwell

2 out of 5
299 Outpost Rd, Seneca, SC
Stay at this cabin in Seneca. Enjoy free parking, patios, and climate control. Popular attractions Friendship Recreaction Area and Cross Creek Plantation Golf ...
9.8/10 Exceptional! (20 reviews)
"Beautiful, relaxing, has everything you nedd"

Reviewed on Aug 12, 2025

Postcard Cabins Lake Hartwell
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Things to do

Cities near Upstate South Carolina