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Check availability on Greenville Luxury Hotels

Tonight
Dec 30 - Dec 31
Tomorrow
Dec 31 - Jan 1
This weekend
Jan 2 - Jan 4
Next weekend
Jan 9 - Jan 11

Our top choices for Greenville luxury hotels

Meeting facility
The Westin Poinsett Greenville

The Westin Poinsett Greenville

The Westin Poinsett Greenville
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1004)
"Great historic hotel. Great location and awesome staff."
United States
John
The price is ￥27,919
￥30,711 total
includes taxes & fees
Jan 11 - Jan 12, 2026
The Westin Poinsett Greenville
Property entrance
Hyatt Regency Greenville

Hyatt Regency Greenville

Hyatt Regency Greenville
3.5 star property
Greenville Downtown
8.6 out of 10, Excellent, (1006)
"clean room, very nice hotel, easy access to food / shopping"
United States
chad
The price is ￥21,056
￥23,856 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Hyatt Regency Greenville
Lobby
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente
2.5 star property
Greenville
8.0 out of 10, Very Good, (1003)
"Convenient to convention center, staff very good, rooms outdated"
United States
candy
The price is ￥13,125
￥14,860 total
includes taxes & fees
Jan 20 - Jan 21, 2026
Sleep Inn at Greenville Convention Cente
2 restaurants, breakfast, lunch, dinner served; American cuisine
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
3.5 star property
Greenville
8.6 out of 10, Excellent, (1000)
"Nice hotel, good staying "
United States
Ricardo
The price is ￥15,129
￥16,642 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Free daily full breakfast
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood
3.0 star property
Greenville
7.4 out of 10, Good, (1132)
"Kind staff, clean room, tasty continental breakfast!"
United States
Karen
The price is ￥11,511
￥12,661 total
includes taxes & fees
Jan 4 - Jan 5, 2026
La Quinta Inn & Suites by Wyndham Greenville Haywood
Terrace/patio
Hilton Greenville

Hilton Greenville

Hilton Greenville
3.5 star property
Greenville
8.2 out of 10, Very Good, (1002)
"Excellent hotel!"
United States
Mary Jane
The price is ￥15,220
￥17,198 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hilton Greenville
Terrace/patio
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
3.5 star property
Greenville
9.0 out of 10, Wonderful, (1013)
"Great stay. "
United States
kurt
The price is ￥15,347
￥16,881 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Embassy Suites Greenville Golf Resort & Conference Center
Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
2.5 star property
Greenville
8.0 out of 10, Very Good, (1007)
"The room was clean, the breakfast was delicious, awesome spread. Staff was friendly. Seamless and smooth."
United States
Pearl
The price is ￥13,195
￥14,983 total
includes taxes & fees
Jan 2 - Jan 3, 2026
Comfort Inn Greenville - Haywood Mall
Indoor pool, outdoor pool
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
3.0 star property
Greenville
9.4 out of 10, Exceptional, (1001)
"We had a great time we will be back "
United States
Tara
The price is ￥16,843
￥18,527 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Drury Inn & Suites Greenville
Front of property
Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville

Days Inn by Wyndham Greenville
2.0 star property
Greenville
5.6 out of 10, (1000)
"Great breakfast "
United States
Jarrod
The price is ￥9,015
￥9,916 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Days Inn by Wyndham Greenville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Greenville Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent
"The room was clean, staffs were welcoming and the breakfast food was good. "
Ngan 1-night trip
Posted 2 days ago
Best Western Plus Greenville I-385 Inn & Suites

Frequently asked questions

Are you searching for the perfect hotel for your luxury holiday in Greenville?
Use Expedia and let us help you arrange a flight to Greenville-Spartanburg Intl. Airport (GSP) airport, and then select from different places to stay that will deliver the luxury you want. Amenities are an important consideration when you plan a vacation, so we make it easy to find what you need to make your stay relaxing and comfortable. If you want a posh hotel that has a spa, an indoor pool, or luxury bedding, Expedia can assist you in finding the best luxury hotel experience that Greenville offers. While you're visiting, you might want to think about enjoying the entertainment and live music, which Greenville is known for.
When can I expect good weather in Greenville?
Planning for the weather is a good way to make your trip to Greenville relaxing and enjoyable, especially when you're splurging. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 46°F. Average annual precipitation for Greenville is 55 inches.
What's there to see and do in Greenville?
Enjoy Greenville with a stop at Centre Stage, The Peace Center, and The Children's Museum of the Upstate. If you have extra time while you're in the area, you might want to see Bon Secours Wellness Arena and Greenville Zoo.
How can I get around Greenville?
It's easier to get around town in style when you know your options. To venture out into the surrounding area, ride aboard one of the trains from Greenville Station.