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Our top choices for Southwest Coast Florida hotels

A modern hotel lobby with a reception desk, seating area, and a dining section.

1. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brian

￥17,819 total

includes taxes & fees

Oct 30 - Oct 31

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

2. Best Western Fort Myers Inn & Suites

Fort Myers

Azael

￥13,459 total

includes taxes & fees

Nov 1 - Nov 2

A Drury Inn & Suites hotel with a parking lot full of cars.

3. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Giselia Dos Santos

￥22,516 total

includes taxes & fees

Nov 2 - Nov 3

An outdoor patio with a barbecue area, seating, and string lights.

4. Homewood Suites by Hilton Fort Myers Airport/FGCU

Miromar Lakes

Leo

￥21,681 total

includes taxes & fees

Nov 29 - Nov 30

A hotel room with a bed, a desk, a chair, and a small table.

5. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Maria

￥15,551 total

includes taxes & fees

Nov 29 - Nov 30

An outdoor patio with yellow chairs and red umbrellas, a fire pit, and a modern building in the background.

6. Home2 Suites by Hilton Fort Myers Airport

Fort Myers

Donna

￥20,079 total

includes taxes & fees

Nov 27 - Nov 28

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

7. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

marleen

￥15,537 total

includes taxes & fees

Oct 31 - Nov 1

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

8. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Merlin

￥11,558 total

includes taxes & fees

Oct 31 - Nov 1

A modern kitchen area with a breakfast bar, fruit display, and a chalkboard menu.

9. Hampton Inn Fort Myers Downtown

Fort Myers River District

Jason

￥20,051 total

includes taxes & fees

Nov 8 - Nov 9

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

10. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Erika

￥13,597 total

includes taxes & fees

Nov 22 - Nov 23

A large, clear swimming pool with multiple lounge areas and palm trees.

11. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Anastasia

￥37,725 total

includes taxes & fees

Nov 1 - Nov 2

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Gabriel

￥17,592 total

includes taxes & fees

Nov 2 - Nov 3

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

13. Embassy Suites by Hilton Fort Myers Estero

Estero

Laura

￥22,496 total

includes taxes & fees

Nov 1 - Nov 2

A reception area with a modern design, featuring a wooden panel wall with integrated lighting, a reception desk, and a refrigerator stocked with beverages.

14. Comfort Suites Fort Myers East I-75

Fort Myers

Eloan

￥15,296 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with a stone fire pit, seating, and string lights.

15. SpringHill Suites by Marriott Fort Myers Estero

Estero

Darryl

￥22,006 total

includes taxes & fees

Nov 2 - Nov 3

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

16. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Julio

￥21,412 total

includes taxes & fees

Nov 22 - Nov 23

A modern kitchen with a breakfast bar, various food items, and a chalkboard menu.

17. Hampton Inn & Suites Fort Myers - Colonial Blvd

Fort Myers

Bibi

￥17,793 total

includes taxes & fees

Nov 29 - Nov 30

A swimming pool with a rock arch structure, a multi-story building with balconies, and palm trees in the background.

18. Pink Shell Beach Resort and Marina

Fort Myers Beach

Mario

￥47,043 total

includes taxes & fees

Nov 29 - Nov 30

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

19. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

￥12,030 total

includes taxes & fees

Nov 3 - Nov 4

20. Quality Inn & Suites Lehigh Acres Fort Myers

Lehigh Acres

arlene

￥10,400 total

includes taxes & fees

Nov 29 - Nov 30

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Vacation Rentals in Southwest Coast Florida

Aparthotel

A beach view from a balcony with a pool, palm trees, and a building with a balcony.

Edison Beach House

Fort Myers Beach

"One of the best locations on Ft Myers Beach"

Apartment

A swimming pool with lounge chairs and a building with a sloped roof in the background.

Landing Apartments Fort Myers near Eastwood Village

Fort Myers

"Extremely clean, very easy check in. Everything is well maintained. Would definitely stay again."

Aparthotel

A beach with a thatched-roof structure, palm trees, and a view of the sea.

The Suites at Fishermen’s Village

Punta Gorda Isles

"Amazing place to stay when visiting Punta Gorda. Very convenient and loved having shops and restaurants so close by. Spacious unit - so much better than just a hotel room."

Aparthotel

A modern hotel room with a kitchenette, a bed, a seating area, and a wardrobe.

StudioRes by Marriott Fort Myers Airport

Fort Myers

"Location was great."

Apartment

A spacious living area with a curved ceiling, large windows, a dining area, and a kitchen.

Landing Furnished Apartments minutes from Downtown Fort Myers

Hancock

"Clean, quiet, perfect alternative to a hotel"

Villa

A compact kitchen with a built-in seating area, a refrigerator, and a ceiling fan.

Matlacha Tiny Village

Matlacha

"So cute and clean nice dock to sit and relax or fish. Kayaks available to use free as well with life jackets paddles, etc. well equipped rental we can’t wait to go again! Great communication with hosts."

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Stay near popular Southwest Coast Florida attractions

A lifeguard tower with an American flag, a green flag, and a signboard on a beach with people sunbathing and umbrellas.

Siesta Key Beach

9.6/10 (4,113 reviews)

The soft, white sand on Siesta Key’s award-winning family-friendly beach is perfect for relaxing under a sun umbrella and taking part in a game of volleyball.

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Learn more about Southwest Coast Florida

Amazing beaches, island views, and top sights from Key West Express to Siesta Key Beach—discover Southwest Coast Florida, a destination also famous for its live music scene.

See all hotels in Southwest Coast Florida

A sunset over a beach with a pier and people walking on the sand.

Top Southwest Coast Florida Hotel Reviews

Lani Kai Beachfront Resort

10/10 Excellent

"Excellent time! Great stay! Super clean and staff is amazing. Love the Italian Restaurant ~ Gracie’s! Beach chairs ~ ❤️ LOVE! Beach front rooms~ awesome views of the sunset! Front desk staff~ super cool and accommodating! Ty!"

Compass Hotel by Margaritaville Anna Maria Sound

10/10 Excellent

"Our room was very clean and modern. The front desk, bartender and each employee we encountered were polite, friendly and helpful. Breakfast was very good. We loved the bar area and took our drinks outside to sit in the patio area. We will definitely be back. The hotels’ location to Anna Maria beaches is very close!"