Find hotels in Santa Cruz, Seville from ¥11,884

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Discover 420 Santa Cruz hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Las Casas de la Judería, Sevilla Historic City Center
4.0 star property
9.2 out of 10, Wonderful, (1015)
"Gorgeous hotel and we loved the uniqueness of the rooms. Comfy beds. Good breakfast and a great location. "
Joanna
The price is ¥22,334
¥24,568 total
includes taxes & fees
Nov 16 - Nov 17
Las Casas de la Judería, Sevilla Historic City Center
Hotel Rey Alfonso X
4.0 star property
9.6 out of 10, Exceptional, (1070)
"Yes all great location staff bar clean etc "
John
The price is ¥35,566
¥39,122 total
includes taxes & fees
Nov 2 - Nov 3
Hotel Rey Alfonso X
Hotel Murillo
2.0 star property
8.6 out of 10, Excellent, (1019)
"Great location. "
fred
Hotel Murillo
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
5.0 star property
9.4 out of 10, Exceptional, (1008)
"A fabulous hotel with fabulous service in the most amazing building "
philippa Ann
The price is ¥90,145
¥99,160 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Fernando III
4.0 star property
9.6 out of 10, Exceptional, (1527)
"Really enjoyed our stay here. The staff was excellent and the location was super convenient and walkable."
Crystal
The price is ¥37,350
¥41,085 total
includes taxes & fees
Oct 18 - Oct 19
Hotel Fernando III
Hotel Murillo Reinoso
2.0 star property
9.4 out of 10, Exceptional, (36)
"Amazing experience, the staff went out their way to make us feel welcome. "
Eunice
The price is ¥14,838
¥16,321 total
includes taxes & fees
Nov 16 - Nov 17
Hotel Murillo Reinoso
Hotel Amadeus Sevilla
4.0 star property
9.6 out of 10, Exceptional, (1045)
"Very nice quaint hotel "
Mark
The price is ¥24,441
¥26,885 total
includes taxes & fees
Nov 16 - Nov 17
Hotel Amadeus Sevilla
Hotel Boutique Corral del Rey by ALUZ Collection
3.0 star property
9.6 out of 10, Exceptional, (85)
"Great hotel!"
Remy Hieu
The price is ¥47,456
¥52,201 total
includes taxes & fees
Oct 21 - Oct 22
Hotel Boutique Corral del Rey by ALUZ Collection
Hotel Convento La Gloria
3.0 star property
8.2 out of 10, Very Good, (613)
"Very friendly staff and willing to meet our requests. "
Lynn
Hotel Convento La Gloria
Eurostars Sevilla Boutique
4.0 star property
9.0 out of 10, Wonderful, (474)
"Very nice hotel in a wonderful location"
Tanya
The price is ¥24,729
¥27,201 total
includes taxes & fees
Nov 16 - Nov 17
Eurostars Sevilla Boutique
Hotel Palacio Alcazar
4.0 star property
9.0 out of 10, Wonderful, (600)
"This is a great location with very friendly staff. Just outside of the cathedral, walking distance from everything. "
Lee
Hotel Palacio Alcazar
Hotel Alcántara
2.0 star property
9.0 out of 10, Wonderful, (816)
"24 hour front desk is very helpful; very good location close to major attractions while still quiet; very friendly staff."
WEN LI
The price is ¥10,804
¥11,884 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Alcántara
Hotel Goya
2.0 star property
8.8 out of 10, Excellent, (664)
"Clean room, restaurants nearby "
Adela
Hotel Goya
Petit Palace Santa Cruz
4.0 star property
9.0 out of 10, Wonderful, (1007)
"Excellent hotel. Probably the friendliest staf"
Mina
The price is ¥19,281
¥21,210 total
includes taxes & fees
Nov 17 - Nov 18
Petit Palace Santa Cruz
EME Catedral Mercer Hotel
5.0 star property
8.8 out of 10, Excellent, (1011)
"A beautiful hotel in an exceptional location. Very friendly staff, especially Emma Martin. Lovely rooftop bar, modern rooms and on the whole a lovely stay. Will be our first choice for our next trip to Seville "
Andy
The price is ¥30,365
¥33,401 total
includes taxes & fees
Nov 16 - Nov 17
EME Catedral Mercer Hotel
Los Seises Sevilla, a Tribute Portfolio Hotel
4.0 star property
8.4 out of 10, Very Good, (494)
"We stayed at Los Seises Seville as a family group of 6 in September 2025. The hotel was perfect for us - great location, professional and friendly staff, excellent accommodation and a rooftop pool with a great view!"
Janet
The price is ¥25,400
¥27,940 total
includes taxes & fees
Nov 16 - Nov 17
Los Seises Sevilla, a Tribute Portfolio Hotel
Hotel Doña Maria
4.0 star property
9.0 out of 10, Wonderful, (1003)
"Staff were helpful and hotel was so close to the center "
Alison
The price is ¥20,127
¥22,139 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Doña Maria
Casa Palacio La Casa Blanca Suites
3.0 star property
9.6 out of 10, Exceptional, (336)
"Amazing place in a perfect location! "
Olga
The price is ¥29,114
¥32,025 total
includes taxes & fees
Oct 28 - Oct 29
Casa Palacio La Casa Blanca Suites
Legado Alcázar Hotel
4.0 star property
9.8 out of 10, Exceptional, (932)
"Great location, Staff was very very accommodating and friendly."
Donovan
The price is ¥26,597
¥29,257 total
includes taxes & fees
Nov 17 - Nov 18
Legado Alcázar Hotel
MDD4 Health Experience Hotel Sevilla - Adults Only
2.0 star property
9.4 out of 10, Exceptional, (31)
"Amazing hotel!!"
Camilo
MDD4 Health Experience Hotel Sevilla - Adults Only
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most.

Historical Center

Go on an adventure through the ages when you visit the historical churches, palaces, plazas and mansions of Seville’s ancient heart.

Alfalfa

Unique features of Alfalfa include the bars and historic sites. Make a stop by Calle Sierpes or Casa de la Memoria Cultural Center while you're exploring the area.

El Arenal

Located in Seville's historical center, El Arenal boasts the 13th-century Torre del Oro, Royal Shipyards, and La Real Maestranza bullring. Explore this vibrant area on the Guadalquivir river's east bank.

Triana

Discover traditional pottery and vibrant flamenco culture in this lively area. Shop at Triana Market for local crafts and tapas, or explore Calle Betis for popular restaurants, bars, and nightclubs.

San Bartolomé

Travelers come to San Bartolomé for its lively bars, and you can see top attractions like Pilate's House and Zurbarán Statue while you're in town.

Top Santa Cruz Hotel Reviews

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Frequently asked questions

What is Santa Cruz like?
Santa Cruz is a historic neighborhood known for its charming cafes and bar scene. Be sure to check out Convent of the Incarnation and Giralda Tower as part of your Santa Cruz travel plans.
What's a favorite place to stay in Santa Cruz?
Based on Expedia customer reviews, Hotel Boutique Casa del Limonero is the highest ranked property in Santa Cruz. This hotel is steps from Giralda Tower, and offers free breakfast and an outdoor pool. Other favorite options in the area include Hotel Boutique Casa del Poeta Sevilla and Joya del Casco Boutique Hotel.
How many hotels will I find in the Santa Cruz area?
If you're searching for places to stay in Seville, Expedia has something to meet your needs with 424 Santa Cruz hotels and other accommodations to choose from.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes, most hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to get the best options available in Santa Cruz.
Where can I learn more about changing or cancelling my trip to Santa Cruz?
For more details about picking new dates or cancelling your trip to Santa Cruz, go to https://www.expedia.com/service/.
What can I see and do in this Seville neighborhood?
Explore Santa Cruz's landmarks like Seville Cathedral, Giralda Tower, and General Archive of the Indies and learn about the local history. You could also plan a visit to Convent of the Incarnation or Juderia de Sevilla Interpretation Center while you're in the neighborhood. A few places to visit in the area around Santa Cruz include Archbishop's Palace, Archiddiocesis de Sevilla, and Triunfo Plaza. While you're out sightseeing in Seville, be sure to visit other sights like Tumba de Cristóbal Colón or Puerta del Príncipe.
How can I get around Santa Cruz and the greater Seville area?
Ready to get out and explore the city? Puerta Jerez Tram Stop is the closest metro station.